Gene Page: PTPRS

Summary
GeneID  5802
Symbol  PTPRS
Synonyms  PTPSIGMA
Description  protein tyrosine phosphatase, receptor type, S
See related  HGNC:9681|MIM:601576|Ensembl:ENSG00000105426|HPRD:03344|
Locus tag  -
Gene type  protein-coding
Map location  19p13.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 0.2273 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
TRAPPC90.860.84
PSMD20.860.85
VPS180.860.86
DDB10.860.88
DGCR20.860.85
PFKL0.850.86
P4HB0.840.84
AP1M10.840.84
VCP0.840.83
ELAC20.840.85
Top 10 negatively co-expressed genes
MT-CO2-0.73-0.77
AF347015.21-0.73-0.77
AF347015.31-0.73-0.75
AF347015.33-0.70-0.73
HIGD1B-0.69-0.70
MT-CYB-0.69-0.72
IFI27-0.68-0.68
AF347015.8-0.68-0.73
AF347015.27-0.68-0.73
NOSTRIN-0.66-0.67
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005001transmembrane receptor protein tyrosine phosphatase activityTAS8524829 
GO:0004872receptor activityIEA-
GO:0005515protein bindingIPI16273344 
GO:0004725protein tyrosine phosphatase activityIEA-
GO:0016787hydrolase activityIEA-
GO:0016791phosphatase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
GO:0006470protein amino acid dephosphorylationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneTAS8524829 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CHD3Mi-2a | Mi2-ALPHA | ZFHchromodomain helicase DNA binding protein 3Two-hybridBioGRID16169070 
EEF1GEF1G | GIG35eukaryotic translation elongation factor 1 gammaTwo-hybridBioGRID16169070 
EIF4A2BM-010 | DDX2B | EIF4A | EIF4Feukaryotic translation initiation factor 4A, isoform 2Affinity Capture-MSBioGRID17353931 
FEZ1-fasciculation and elongation protein zeta 1 (zygin I)Two-hybridBioGRID16169070 
KAT5ESA1 | HTATIP | HTATIP1 | PLIP | TIP | TIP60 | cPLA2K(lysine) acetyltransferase 5Two-hybridBioGRID16169070 
KIAA1377-KIAA1377Two-hybridBioGRID16169070 
MOBKL32C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3MOB1, Mps One Binder kinase activator-like 3 (yeast)Two-hybridBioGRID16169070 
PFN2D3S1319E | PFLprofilin 2Two-hybridBioGRID16169070 
PPFIA1FLJ41337 | FLJ42630 | FLJ43474 | LIP.1 | LIP1 | LIPRIN | MGC26800protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1-HPRD,BioGRID8524829 
PPFIA2FLJ41378 | MGC132572protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2-HPRD,BioGRID9624153 
PPFIA3KIAA0654 | LPNA3 | MGC126567 | MGC126569protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3-HPRD,BioGRID9624153 
PTNHARP | HBGF8 | HBNF | NEGF1pleiotrophinTwo-hybridBioGRID16169070 
PTPRDHPTP | HPTP-DELTA | HPTPD | MGC119750 | MGC119751 | MGC119752 | MGC119753 | PTPD | R-PTP-DELTAprotein tyrosine phosphatase, receptor type, D-HPRD,BioGRID9566880 
SETDB1ESET | KG1T | KIAA0067 | KMT1ESET domain, bifurcated 1Two-hybridBioGRID16169070 
TUBB2ATUBB | TUBB2 | dJ40E16.7tubulin, beta 2ATwo-hybridBioGRID16169070 
UBR1JBS | MGC142065 | MGC142067ubiquitin protein ligase E3 component n-recognin 1Two-hybridBioGRID16169070 
UNC119HRG4unc-119 homolog (C. elegans)Two-hybridBioGRID16169070 
UTP14AKIAA0266 | NY-CO-16 | SDCCAG16 | dJ537K23.3UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ODONNELL_TFRC_TARGETS_UP 456228All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN 770415All SZGR genes in this pathway
HUMMERICH_SKIN_CANCER_PROGRESSION_DN 10064All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP 10969All SZGR genes in this pathway
SUNG_METASTASIS_STROMA_UP 11070All SZGR genes in this pathway
MOREAUX_MULTIPLE_MYELOMA_BY_TACI_UP 412249All SZGR genes in this pathway
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_UP 9258All SZGR genes in this pathway
URS_ADIPOCYTE_DIFFERENTIATION_UP 7451All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP 12589All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP 14985All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_UP 13995All SZGR genes in this pathway
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_DN 7247All SZGR genes in this pathway
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_DN 5033All SZGR genes in this pathway
HOFMANN_MYELODYSPLASTIC_SYNDROM_LOW_RISK_UP 2215All SZGR genes in this pathway
HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP 107All SZGR genes in this pathway
MILI_PSEUDOPODIA_HAPTOTAXIS_DN 668419All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_UP 166105All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_1_DN 4830All SZGR genes in this pathway
FIGUEROA_AML_METHYLATION_CLUSTER_4_DN 159All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN 321200All SZGR genes in this pathway
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 824528All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-1908308371A,m8hsa-miR-190UGAUAUGUUUGAUAUAUUAGGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.