Gene Page: S100A8

Summary
GeneID  6279
Symbol  S100A8
Synonyms  60B8AG|CAGA|CFAG|CGLA|CP-10|L1Ag|MA387|MIF|MRP8|NIF|P8
Description  S100 calcium binding protein A8
See related  HGNC:10498|MIM:123885|Ensembl:ENSG00000143546|HPRD:00471|
Locus tag  -
Gene type  protein-coding
Map location  1q21
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.0235 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.00814 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingTAS2149559 
GO:0005515protein bindingIPI17353931 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006954inflammatory responseTAS3313057 
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ASB3ASB-3 | FLJ10123 | FLJ10421 | MGC12531 | MGC132002 | MGC996ankyrin repeat and SOCS box-containing 3Affinity Capture-MSBioGRID17353931 
C14orf1ERG28 | NET51chromosome 14 open reading frame 1Two-hybridBioGRID16169070 
C1orf103FLJ11269 | RIF1 | RP11-96K19.1chromosome 1 open reading frame 103Two-hybridBioGRID16169070 
CEACAM3CD66D | CEA | CGM1 | MGC119875 | W264 | W282carcinoembryonic antigen-related cell adhesion molecule 3-HPRD11708798 
CHGBSCG1chromogranin B (secretogranin 1)Two-hybridBioGRID16169070 
GDF9-growth differentiation factor 9Two-hybridBioGRID16169070 
IGSF21FLJ41177 | MGC15730immunoglobin superfamily, member 21Two-hybridBioGRID16169070 
LRRK1FLJ23119 | FLJ27465 | KIAA1790 | RIPK6 | Roco1leucine-rich repeat kinase 1Affinity Capture-MSBioGRID17353931 
MOBKL1BC2orf6 | FLJ10788 | FLJ11595 | MATS1 | MOB1 | MOBK1B | Mob4BMOB1, Mps One Binder kinase activator-like 1B (yeast)Affinity Capture-MSBioGRID17353931 
NUAK1ARK5 | KIAA0537NUAK family, SNF1-like kinase, 1Affinity Capture-MSBioGRID17353931 
PDCD11ALG-4 | ALG4 | KIAA0185 | NFBPprogrammed cell death 11Two-hybridBioGRID16169070 
PPIACYPA | CYPH | MGC117158 | MGC12404 | MGC23397peptidylprolyl isomerase A (cyclophilin A)Two-hybridBioGRID16169070 
PPM1BMGC21657 | PP2C-beta-X | PP2CB | PP2CBETA | PPC2BETAXprotein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoformAffinity Capture-MSBioGRID17353931 
PRMT1ANM1 | HCP1 | HRMT1L2 | IR1B4protein arginine methyltransferase 1Two-hybridBioGRID16169070 
S100A860B8AG | CAGA | CFAG | CGLA | CP-10 | L1Ag | MA387 | MIF | MRP8 | NIF | P8S100 calcium binding protein A8-HPRD,BioGRID10771424 
S100A960B8AG | CAGB | CFAG | CGLB | L1AG | LIAG | MAC387 | MIF | MRP14 | NIF | P14S100 calcium binding protein A9-HPRD11867565 
TP53FLJ92943 | LFS1 | TRP53 | p53tumor protein p53Two-hybridBioGRID16169070 
UNC119HRG4unc-119 homolog (C. elegans)Two-hybridBioGRID16169070 
USF2FIP | bHLHb12upstream transcription factor 2, c-fos interactingAffinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_TOLL_ENDOGENOUS_PATHWAY 2519All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_WITH_LMP1_DN 17582All SZGR genes in this pathway
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN 11679All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP 450256All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP 12145All SZGR genes in this pathway
DOANE_BREAST_CANCER_ESR1_DN 4828All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
JAEGER_METASTASIS_DN 258141All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_3D_DN 3119All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN 205127All SZGR genes in this pathway
PEPPER_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP 3328All SZGR genes in this pathway
RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP 7841All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_UP 14175All SZGR genes in this pathway
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN 226132All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
ENK_UV_RESPONSE_EPIDERMIS_UP 293179All SZGR genes in this pathway
WANG_BARRETTS_ESOPHAGUS_DN 2513All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_5_6WK_UP 11668All SZGR genes in this pathway
MCBRYAN_PUBERTAL_BREAST_6_7WK_DN 7954All SZGR genes in this pathway
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP 5232All SZGR genes in this pathway
HUMMERICH_BENIGN_SKIN_TUMOR_UP 188All SZGR genes in this pathway
HUMMERICH_MALIGNANT_SKIN_TUMOR_UP 168All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_UP 14296All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_UP 162104All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_UP 147101All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP 146104All SZGR genes in this pathway
OLSSON_E2F3_TARGETS_UP 2814All SZGR genes in this pathway
RASHI_RESPONSE_TO_IONIZING_RADIATION_6 8454All SZGR genes in this pathway
MATTIOLI_MGUS_VS_PCL 11662All SZGR genes in this pathway
FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL 326213All SZGR genes in this pathway
AIYAR_COBRA1_TARGETS_UP 3925All SZGR genes in this pathway
GROSS_HYPOXIA_VIA_ELK3_DN 156106All SZGR genes in this pathway
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN 382224All SZGR genes in this pathway
GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN 206136All SZGR genes in this pathway
SHIN_B_CELL_LYMPHOMA_CLUSTER_6 119All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
KENNY_CTNNB1_TARGETS_UP 5030All SZGR genes in this pathway
ROSS_AML_WITH_CBFB_MYH11_FUSION 5232All SZGR genes in this pathway
JECHLINGER_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP 7151All SZGR genes in this pathway
NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_DN 12179All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP 8758All SZGR genes in this pathway
CHEOK_RESPONSE_TO_HD_MTX_UP 2313All SZGR genes in this pathway
LEI_MYB_TARGETS 318215All SZGR genes in this pathway
LENAOUR_DENDRITIC_CELL_MATURATION_DN 12890All SZGR genes in this pathway
GERY_CEBP_TARGETS 12690All SZGR genes in this pathway
BENNETT_SYSTEMIC_LUPUS_ERYTHEMATOSUS 3121All SZGR genes in this pathway
HADDAD_T_LYMPHOCYTE_AND_NK_PROGENITOR_DN 6341All SZGR genes in this pathway
SCHLINGEMANN_SKIN_CARCINOGENESIS_TPA_UP 4224All SZGR genes in this pathway
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_DN 4232All SZGR genes in this pathway
MCDOWELL_ACUTE_LUNG_INJURY_UP 4529All SZGR genes in this pathway
WANG_SMARCE1_TARGETS_DN 371218All SZGR genes in this pathway
BURTON_ADIPOGENESIS_PEAK_AT_24HR 4330All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_DN 245144All SZGR genes in this pathway
MCLACHLAN_DENTAL_CARIES_UP 253147All SZGR genes in this pathway
BURTON_ADIPOGENESIS_6 189112All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN 911527All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
RIGGINS_TAMOXIFEN_RESISTANCE_DN 220147All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_UP 602364All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_UP 601369All SZGR genes in this pathway
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN 154101All SZGR genes in this pathway
YAMASHITA_METHYLATED_IN_PROSTATE_CANCER 5729All SZGR genes in this pathway
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN 315197All SZGR genes in this pathway
SMID_BREAST_CANCER_LUMINAL_B_DN 564326All SZGR genes in this pathway
SMID_BREAST_CANCER_ERBB2_UP 14783All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
ZHENG_IL22_SIGNALING_UP 5636All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_UP 5429All SZGR genes in this pathway
DAVIES_MULTIPLE_MYELOMA_VS_MGUS_DN 2818All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_C_D_DN 252155All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_DN 435289All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
BOYLAN_MULTIPLE_MYELOMA_PCA1_UP 10166All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
GUTIERREZ_WALDENSTROEMS_MACROGLOBULINEMIA_1_DN 97All SZGR genes in this pathway
CHANDRAN_METASTASIS_UP 221135All SZGR genes in this pathway
KAMIKUBO_MYELOID_CEBPA_NETWORK 2819All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_DN 8859All SZGR genes in this pathway
KIM_ALL_DISORDERS_CALB1_CORR_DN 3720All SZGR genes in this pathway
CHYLA_CBFA2T3_TARGETS_DN 242146All SZGR genes in this pathway
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP 12170All SZGR genes in this pathway
LEE_BMP2_TARGETS_DN 882538All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
KUMAR_PATHOGEN_LOAD_BY_MACROPHAGES 275155All SZGR genes in this pathway
LIM_MAMMARY_LUMINAL_PROGENITOR_UP 5830All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
NABA_SECRETED_FACTORS 344197All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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