Gene Page: SLC6A6

Summary
GeneID  6533
Symbol  SLC6A6
Synonyms  MGC10619|MGC131729|TAUT
Description  solute carrier family 6 (neurotransmitter transporter, taurine), member 6
See related  HGNC:11052|MIM:186854|Ensembl:ENSG00000131389|HPRD:01734|
Locus tag  -
Gene type  protein-coding
Map location  3p25-p24
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005369taurine:sodium symporter activityIEANeurotransmitter (GO term level: 10)-
GO:0005369taurine:sodium symporter activityTASNeurotransmitter (GO term level: 10)8010975 
GO:0001761beta-alanine transmembrane transporter activityIEA-
GO:0015293symporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006836neurotransmitter transportIEAneuron, Neurotransmitter (GO term level: 5)-
GO:0001762beta-alanine transportIEA-
GO:0006520amino acid metabolic processTAS8010975 
GO:0015734taurine transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0005887integral to plasma membraneIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
REACTOME_AMINO_ACID_TRANSPORT_ACROSS_THE_PLASMA_MEMBRANE 3121All SZGR genes in this pathway
REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 413270All SZGR genes in this pathway
REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT 241157All SZGR genes in this pathway
REACTOME_TRANSPORT_OF_GLUCOSE_AND_OTHER_SUGARS_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS 8954All SZGR genes in this pathway
REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES 9465All SZGR genes in this pathway
REACTOME_AMINO_ACID_AND_OLIGOPEPTIDE_SLC_TRANSPORTERS 4936All SZGR genes in this pathway
REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS 1712All SZGR genes in this pathway
REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS 2716All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP 579346All SZGR genes in this pathway
GAL_LEUKEMIC_STEM_CELL_DN 244153All SZGR genes in this pathway
SENESE_HDAC1_TARGETS_UP 457269All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
SABATES_COLORECTAL_ADENOMA_UP 14175All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
HOWLIN_PUBERTAL_MAMMARY_GLAND 6940All SZGR genes in this pathway
PUJANA_BRCA1_PCC_NETWORK 16521023All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP 811508All SZGR genes in this pathway
BROWN_MYELOID_CELL_DEVELOPMENT_UP 165100All SZGR genes in this pathway
GUO_HEX_TARGETS_UP 8154All SZGR genes in this pathway
KANG_IMMORTALIZED_BY_TERT_UP 8961All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_20HR_UP 240152All SZGR genes in this pathway
BURTON_ADIPOGENESIS_2 7252All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_6HR_UP 7148All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
SANSOM_APC_MYC_TARGETS 217138All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
WINTER_HYPOXIA_METAGENE 242168All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
ZHANG_TLX_TARGETS_60HR_UP 293203All SZGR genes in this pathway
CHEN_METABOLIC_SYNDROM_NETWORK 1210725All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
WONG_ADULT_TISSUE_STEM_MODULE 721492All SZGR genes in this pathway
MARTENS_BOUND_BY_PML_RARA_FUSION 456287All SZGR genes in this pathway
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN 374217All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
BHAT_ESR1_TARGETS_VIA_AKT1_UP 281183All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
FEVR_CTNNB1_TARGETS_UP 682433All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway
IKEDA_MIR133_TARGETS_UP 4327All SZGR genes in this pathway
IKEDA_MIR30_TARGETS_UP 11687All SZGR genes in this pathway
FORTSCHEGGER_PHF8_TARGETS_DN 784464All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-128394439501Ahsa-miR-128aUCACAGUGAACCGGUCUCUUUU
hsa-miR-128bUCACAGUGAACCGGUCUCUUUC
miR-133111411201Ahsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-137408414m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-1826346401Ahsa-miR-182UUUGGCAAUGGUAGAACUCACA
miR-18316171623m8hsa-miR-183UAUGGCACUGGUAGAAUUCACUG
miR-200bc/42921682174m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-203.143214327m8hsa-miR-203UGAAAUGUUUAGGACCACUAG
miR-217415641621Ahsa-miR-217UACUGCAUCAGGAACUGAUUGGAU
miR-218396139671Ahsa-miR-218brainUUGUGCUUGAUCUAACCAUGU
miR-263663721Ahsa-miR-26abrainUUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZUUCAAGUAAUUCAGGAUAGGUU
miR-2739443950m8hsa-miR-27abrainUUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrainUUCACAGUGGCUAAGUUCUGC
miR-30-5p69751Ahsa-miR-30a-5pUGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrainUGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZUGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZUGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5pUGUAAACAUCCUUGACUGGA
miR-313803871A,m8hsa-miR-31AGGCAAGAUGCUGGCAUAGCUG
miR-38430763082m8hsa-miR-384AUUCCUAGAAAUUGUUCAUA
miR-4906571m8hsa-miR-490CAACCUGGAGGACUCCAUGCUG
miR-493-5p2102161Ahsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-542-3p1161221Ahsa-miR-542-3pUGUGACAGAUUGAUAACUGAAA
miR-9225722641A,m8hsa-miR-9SZUCUUUGGUUAUCUAGCUGUAUGA
miR-966346401Ahsa-miR-96brainUUUGGCACUAGCACAUUUUUGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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