Gene Page: SLIT3

Summary
GeneID  6586
Symbol  SLIT3
Synonyms  FLJ10764|MEGF5|SLIL2|SLIT1|Slit-3|slit2
Description  slit homolog 3 (Drosophila)
See related  HGNC:11087|MIM:603745|Ensembl:ENSG00000184347|HPRD:04775|
Locus tag  -
Gene type  protein-coding
Map location  5q35
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies1Link to SZGene
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.0276 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
DDX390.950.89
AAAS0.950.90
RNASEH2A0.940.88
IMPDH20.940.93
TRIM280.930.94
WRAP530.930.91
SMARCB10.930.94
RALY0.930.92
MAD2L20.930.88
BAT10.930.92
Top 10 negatively co-expressed genes
AF347015.27-0.68-0.86
AF347015.31-0.68-0.85
C5orf53-0.68-0.75
MT-CO2-0.68-0.86
AF347015.33-0.67-0.85
MT-CYB-0.66-0.84
HLA-F-0.65-0.73
AF347015.8-0.65-0.85
AIFM3-0.65-0.72
S100B-0.64-0.78
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingNAS-
GO:0005515protein bindingTAS9813312 
GO:0005198structural molecule activityNAS-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentTASBrain (GO term level: 6)10349621 
GO:0007411axon guidanceIEAaxon (GO term level: 13)-
GO:0009887organ morphogenesisIEA-
GO:0007275multicellular organismal developmentTAS9813312 
GO:0030154cell differentiationIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS9813312 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CAPN1CANP | CANP1 | CANPL1 | muCANP | muCLcalpain 1, (mu/I) large subunitCAPN1 interacts with SLIT3.BIND12358155 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_AXON_GUIDANCE 129103All SZGR genes in this pathway
REACTOME_DEVELOPMENTAL_BIOLOGY 396292All SZGR genes in this pathway
REACTOME_AXON_GUIDANCE 251188All SZGR genes in this pathway
REACTOME_NETRIN1_SIGNALING 4130All SZGR genes in this pathway
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN 169118All SZGR genes in this pathway
MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP 276165All SZGR genes in this pathway
MULLIGHAN_NPM1_SIGNATURE_3_UP 341197All SZGR genes in this pathway
CHEBOTAEV_GR_TARGETS_UP 7762All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_A_DN 9061All SZGR genes in this pathway
BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_UP 6045All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_DN 712443All SZGR genes in this pathway
KOYAMA_SEMA3B_TARGETS_DN 411249All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
CHANG_POU5F1_TARGETS_UP 1510All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_DN 185111All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
MAHAJAN_RESPONSE_TO_IL1A_DN 7657All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_DN 8056All SZGR genes in this pathway
MARTINEZ_RB1_TARGETS_DN 543317All SZGR genes in this pathway
MARTINEZ_TP53_TARGETS_DN 593372All SZGR genes in this pathway
MARTINEZ_RB1_AND_TP53_TARGETS_DN 591366All SZGR genes in this pathway
RIZKI_TUMOR_INVASIVENESS_3D_DN 270181All SZGR genes in this pathway
RIGGI_EWING_SARCOMA_PROGENITOR_DN 191123All SZGR genes in this pathway
SMID_BREAST_CANCER_NORMAL_LIKE_UP 476285All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_DN 701446All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA 7752All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_DN 366257All SZGR genes in this pathway
HOSHIDA_LIVER_CANCER_SURVIVAL_UP 7349All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP 344215All SZGR genes in this pathway
WANG_MLL_TARGETS 289188All SZGR genes in this pathway
ROLEF_GLIS3_TARGETS 3729All SZGR genes in this pathway
PEDRIOLI_MIR31_TARGETS_DN 418245All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY 1839928All SZGR genes in this pathway
NABA_ECM_GLYCOPROTEINS 19699All SZGR genes in this pathway
NABA_CORE_MATRISOME 275148All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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