| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20030137 | HPV | ENSG00000103546.19 | protein_coding | SLC6A2 | No | No | 6530 | P23975 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC6A2 |
|---|---|
| DrugBank ID | DB01104 |
| Drug Name | Sertraline |
| Target ID | BE0000486 |
| UniProt ID | P23975 |
| Regulation Type | inhibitor |
| PubMed IDs | 9537821; 23086945 |
| Citations | Tatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.@@Sorensen L, Andersen J, Thomsen M, Hansen SM, Zhao X, Sandelin A, Stromgaard K, Kristensen AS: Interaction of antidepressants with the serotonin and norepinephrine transporters: mutational studies of the S1 substrate binding pocket. J Biol Chem. 2012 Dec 21;287(52):43694-707. doi: 10.1074/jbc.M112.342212. Epub 2012 Oct 19. |
| Groups | Approved |
| Direct Classification | Tametralines |
| SMILES | CN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA451333 |
| ChEMBL | CHEMBL809 |
