Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB09068
Drug NameVortioxetine
Target IDBE0000486
UniProt IDP23975
Regulation Typeblocker
PubMed IDs21486038
CitationsBang-Andersen B, Ruhland T, Jorgensen M, Smith G, Frederiksen K, Jensen KG, Zhong H, Nielsen SM, Hogg S, Mork A, Stensbol TB: Discovery of 1-[2-(2,4-dimethylphenylsulfanyl)phenyl]piperazine (Lu AA21004): a novel multimodal compound for the treatment of major depressive disorder. J Med Chem. 2011 May 12;54(9):3206-21. doi: 10.1021/jm101459g. Epub 2011 Apr 12.
GroupsApproved; Investigational
Direct Classification
SMILESCC1=CC=C(SC2=CC=CC=C2N2CCNCC2)C(C)=C1
Pathways
PharmGKBPA166122595
ChEMBLCHEMBL2104993