Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB09167
Drug NameDosulepin
Target IDBE0000486
UniProt IDP23975
Regulation Typeinhibitor
PubMed IDs17471183; 18293180
CitationsGillman PK: Tricyclic antidepressant pharmacology and therapeutic drug interactions updated. Br J Pharmacol. 2007 Jul;151(6):737-48. Epub 2007 Apr 30.@@Wille SM, Cooreman SG, Neels HM, Lambert WE: Relevant issues in the monitoring and the toxicology of antidepressants. Crit Rev Clin Lab Sci. 2008;45(1):25-89. doi: 10.1080/10408360701713112 .
GroupsApproved
Direct ClassificationDibenzothiepins
SMILESCN(C)CCC=C1/C2=CC=CC=C2CSC2=CC=CC=C12
Pathways
PharmGKB
ChEMBLCHEMBL1492500