| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20030137 | HPV | ENSG00000103546.19 | protein_coding | SLC6A2 | No | No | 6530 | P23975 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC6A2 |
|---|---|
| DrugBank ID | DB01576 |
| Drug Name | Dextroamphetamine |
| Target ID | BE0000486 |
| UniProt ID | P23975 |
| Regulation Type | negative modulator |
| PubMed IDs | 17239355; 19727679; 8794928 |
| Citations | Dlugos A, Freitag C, Hohoff C, McDonald J, Cook EH, Deckert J, de Wit H: Norepinephrine transporter gene variation modulates acute response to D-amphetamine. Biol Psychiatry. 2007 Jun 1;61(11):1296-305. Epub 2007 Jan 17.@@Dlugos AM, Hamidovic A, Palmer AA, de Wit H: Further evidence of association between amphetamine response and SLC6A2 gene variants. Psychopharmacology (Berl). 2009 Oct;206(3):501-11. doi: 10.1007/s00213-009-1628-y.@@Burnette WB, Bailey MD, Kukoyi S, Blakely RD, Trowbridge CG, Justice JB Jr: Human norepinephrine transporter kinetics using rotating disk electrode voltammetry. Anal Chem. 1996 Sep 1;68(17):2932-8. |
| Groups | Approved; Illicit |
| Direct Classification | Amphetamines and derivatives |
| SMILES | C[C@H](N)CC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA449269 |
| ChEMBL | CHEMBL612 |
