Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB01242
Drug NameClomipramine
Target IDBE0000486
UniProt IDP23975
Regulation Typeinhibitor
PubMed IDs9537821; 11341486
CitationsTatsumi M, Groshan K, Blakely RD, Richelson E: Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol. 1997 Dec 11;340(2-3):249-58.@@Jungkun G, Kuss HJ, Gsell W: Long-term effects of tricyclic antidepressants on norepinephrine kinetics in humans. J Neural Transm (Vienna). 2001;108(3):349-62.
GroupsApproved; Investigational; Vet_approved
Direct ClassificationDibenzazepines
SMILESCN(C)CCCN1C2=CC=CC=C2CCC2=C1C=C(Cl)C=C2
PathwaysClomipramine Metabolism Pathway
PharmGKBPA449048
ChEMBLCHEMBL415