DegronMD

Uniprot ID: Q8IZF6

Source protein: Adhesion G-protein coupled receptor G4

Source gene: ADGRG4

Class: DEG_SPOP_SBC_1

Location: 1963:1967

E3 ligase: SPOP

DEGRON score: 0.998

ASA_SCORE: 80.4

COIL: 0.782

CONS_SCORE: 0.7514

DSS_SCORE: 0.3495

HELIX: 0.0164

FCONS_SCORE: 0.9734

RIG_SCORE: 0.7678

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.L1973I	NCI-H835	lung	COSMIC	AITST	DEG_SPOP_SBC_1	0.1667

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q02505	Mucin-3A	DEG_SPOP_SBC_1	1685:1689	AITST	SPOP	0.8556	More...
Q05586	Glutamate receptor ionotropic, NMDA 1	DEG_SPOP_SBC_1	882:886	AITST	SPOP	0.8412	More...
Q8IZF6	Adhesion G-protein coupled receptor G4	DEG_SPOP_SBC_1	1963:1967	AITST	SPOP	0.998	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons