DegronMD

Uniprot ID: Q96T37

Source protein: RNA-binding protein 15

Source gene: RBM15

Class: DEG_SCF_TRCP1_1

Location: 89:94

E3 ligase: BTRC

DEGRON score: 0.9617

ASA_SCORE: 74.35

COIL: 0.9582

CONS_SCORE: 0.2948

DSS_SCORE: 0.7183

HELIX: 0.023

FCONS_SCORE: 0.9361

RIG_SCORE: 0.501

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D89N	TCGA-KQ-A41S	BLCA	TCGA	DSGGGS	DEG_SCF_TRCP1_1	0.6932
p.D89N	DO223593	BLCA	ICGC	DSGGGS	DEG_SCF_TRCP1_1	0.6932
p.G92S	DO223460	CLLE	ICGC	DSGGGS	DEG_SCF_TRCP1_1	0.5882
p.S103F	ACH-000969	Colon/Colorectal Cancer	CCLE	DSGGGS	DEG_SCF_TRCP1_1	0.5278
p.S94A	ACH-001047	Lung Cancer	CCLE	DSGGGS	DEG_SCF_TRCP1_1	0.7588

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q96T37	RNA-binding protein 15	DEG_SCF_TRCP1_1	89:94	DSGGGS	BTRC	0.9617	More...
Q9Y462	Zinc finger protein 711	DEG_SCF_TRCP1_1	2:7	DSGGGS	BTRC	0.9877	More...
Q6NY19	KN motif and ankyrin repeat domain-containing protein 3	DEG_SCF_TRCP1_1	509:514	DSGGGS	BTRC	0.997	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons