Degron: MATPSSS
Mucin-5B
MUC5B
2117:2123
FBXW7
0.9433
90.0857
0.9406
0.213
0.6324
0.0154
0.9208
0.659
Degron related mutations and impact score
Mutation |
Sample |
Cancer |
Dataset |
Degron |
Degron class |
Impact score |
p.S2127N | TCGA-CC-5264 | LIHC | TCGA | MATPSSS | DEG_SCF_FBW7_1 | 0.2222 |
p.S2122C | TCGA-OL-A5DA | BRCA | TCGA | MATPSSS | DEG_SCF_FBW7_1 | 0.643 |
p.S2125C | DO44121 | BRCA | ICGC | MATPSSS | DEG_SCF_FBW7_1 | 0.2778 |
p.T2132I | DO50970 | LICA | ICGC | MATPSSS | DEG_SCF_FBW7_1 | 0.0833 |
p.S2130N | DO23053 | LIHC | ICGC | MATPSSS | DEG_SCF_FBW7_1 | 0.1389 |
p.T2114N | DO229229 | THCA | ICGC | MATPSSS | DEG_SCF_FBW7_1 | 0.25 |
p.P2131L | ACH-000785 | Lung Cancer | CCLE | MATPSSS | DEG_SCF_FBW7_1 | 0.1111 |
Drug responses associated with MUC5B mutations
Sample |
Cancer |
Mutation (In Degron?) |
Dataset |
Drug |
IC50 |
All proteins holding degron of MATPSSS