DegronMD - Q9HC84(MUC5B)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T2698M	TCGA-04-1652	OV	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.1111
p.T2698M	SIDM00901	Endometrial Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.1111
p.T2698M	ACH-000971	Colon/Colorectal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.1111
p.P3687L	TCGA-04-1652	OV	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P3687L	TCGA-BS-A0UV	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P3687L	TCGA-BT-A20J	BLCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P3687L	TCGA-N7-A4Y0	UCS	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P2596S	TCGA-05-4389	LUAD	TCGA	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6752
p.P3712Q	TCGA-05-4390	LUAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7035
p.T4845N	TCGA-05-4417	LUAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.7055
p.W4846R	TCGA-05-4417	LUAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.3056
p.R4904H	TCGA-06-0219	GBM	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	TCGA-55-A4DG	LUAD	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	TCGA-EO-A22X	UCEC	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	SIDM00963	Breast Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	SIDM00382	Glioblastoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	SIDM01609	Endometrial Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	SIDM01608	Endometrial Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	ACH-000609	Brain Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	ACH-000914	Lymphoma	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.R4904H	ACH-000927	Breast Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.A4742T	TCGA-06-5416	GBM	TCGA	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.3056
p.A4766T	TCGA-06-5416	GBM	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation altering degron motif	0.7139
p.T1896M	TCGA-12-3651	GBM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.T1896M	TCGA-12-3651	GBM	TCGA	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.25
p.T1896M	TCGA-12-3651	GBM	TCGA	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0556
p.T1896M	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.T1896M	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.25
p.T1896M	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0556
p.T1896M	ACH-000717	Esophageal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.T1896M	ACH-000717	Esophageal Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.25
p.T1896M	ACH-000717	Esophageal Cancer	CCLE	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0556
p.T1896M	COLO-680N	oesophagus	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.T1896M	COLO-680N	oesophagus	COSMIC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.25
p.T1896M	COLO-680N	oesophagus	COSMIC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0556
p.P3910S	TCGA-18-3409	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1111
p.P2620H	TCGA-21-5787	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.1111
p.T4761M	TCGA-22-4591	LUSC	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1944
p.T4761M	TCGA-G3-A5SI	LIHC	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1944
p.T4761M	TCGA-IB-7651	PAAD	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1944
p.P2268Q	TCGA-22-4613	LUSC	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation altering degron motif	0.7035
p.P3100T	TCGA-22-5492	LUSC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.7031
p.S4313G	TCGA-23-2084	OV	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.6993
p.T2062I	TCGA-24-1427	OV	TCGA	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1389
p.P1637L	TCGA-2H-A9GN	ESCA	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.0833
p.P1637L	TCGA-2H-A9GN	ESCA	TCGA	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1389
p.A1758T	TCGA-2W-A8YY	CESC	TCGA	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7139
p.P2039R	TCGA-34-5239	LUSC	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7512
p.T3923S	TCGA-34-5929	LUSC	TCGA	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.1111
p.T3923S	TCGA-34-5929	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.3056
p.T2262S	TCGA-37-3792	LUSC	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.G3688E	TCGA-37-4132	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.6087
p.G3688E	TCGA-P3-A6T7	HNSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.6087
p.P4309A	TCGA-37-A5EL	LUSC	TCGA	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.0833
p.P4309A	TCGA-37-A5EL	LUSC	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.3056
p.A3497G	TCGA-39-5039	LUSC	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.6429
p.V4900M	TCGA-3M-AB47	STAD	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.2778
p.V4900M	TCGA-DU-6392	LGG	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.2778
p.T4321N	TCGA-44-2668	LUAD	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.2778
p.T4321N	TCGA-44-2668	LUAD	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.R3117K	TCGA-44-7662	LUAD	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1944
p.L957I	TCGA-44-7667	LUAD	TCGA	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation altering degron motif	0.6063
p.T3035I	TCGA-44-7671	LUAD	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1389
p.T3035I	TCGA-44-7671	LUAD	TCGA	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.2222
p.R3117W	TCGA-49-6743	LUAD	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1944
p.R3117M	TCGA-49-6743	LUAD	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1944
p.P3712A	TCGA-49-6767	LUAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7503
p.T2582N	TCGA-49-AARE	LUAD	TCGA	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation altering degron motif	0.7055
p.T2582N	TCGA-NK-A5CT	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation altering degron motif	0.7055
p.L4331H	TCGA-49-AARQ	LUAD	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.25
p.T4434I	TCGA-4X-A9FD	THYM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1667
p.T2271N	TCGA-51-4081	LUSC	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation altering degron motif	0.7055
p.S1987F	TCGA-55-6983	LUAD	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.2778
p.P3523T	TCGA-55-6985	LUAD	TCGA	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2778
p.G2058A	TCGA-55-8094	LUAD	TCGA	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.25
p.S4726Y	TCGA-55-8204	LUAD	TCGA	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation altering degron motif	0.712
p.P3857T	TCGA-55-A490	LUAD	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.3056
p.P3857T	TCGA-55-A490	LUAD	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1111
p.P2571A	TCGA-56-7223	LUSC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.25
p.P2571A	TCGA-56-7223	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.S3127T	TCGA-56-7823	LUSC	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.6005
p.T1675K	TCGA-56-8083	LUSC	TCGA	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.6195
p.P3021S	TCGA-58-8386	LUSC	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.25
p.S2428C	TCGA-58-A46K	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.643
p.T2974N	TCGA-63-7020	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.0833
p.P4643L	TCGA-63-7023	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1111
p.S4355C	TCGA-66-2744	LUSC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.643
p.T2570S	TCGA-66-2763	LUSC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.2222
p.T2570S	TCGA-66-2763	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.0833
p.T3270S	TCGA-66-2763	LUSC	TCGA	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.2222
p.T3270S	TCGA-66-2763	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.0833
p.T1663R	TCGA-66-2766	LUSC	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.0556
p.T2276S	TCGA-66-2766	LUSC	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2222
p.T2980M	TCGA-66-2787	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.25
p.T2980M	TCGA-BS-A0U8	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.25
p.E4423K	TCGA-67-3771	LUAD	TCGA	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.0833
p.T4893M	TCGA-69-7763	LUAD	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.3056
p.T4893M	SIDM00282	Colorectal Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.3056
p.T4893M	SIDM00327	Hodgkin's Lymphoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.3056
p.T1929I	TCGA-76-4927	GBM	TCGA	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.0833
p.G3848S	TCGA-77-8128	LUSC	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2778
p.G3848S	TCGA-77-8128	LUSC	TCGA	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1111
p.G3848S	TCGA-B5-A3FC	UCEC	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2778
p.G3848S	TCGA-B5-A3FC	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1111
p.G3848S	TCGA-D1-A17Q	UCEC	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2778
p.G3848S	TCGA-D1-A17Q	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1111
p.G3848S	SIDM00068	Colorectal Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2778
p.G3848S	SIDM00068	Colorectal Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1111
p.G3848S	GEO	large intestine	COSMIC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2778
p.G3848S	GEO	large intestine	COSMIC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1111
p.P2063T	TCGA-77-8156	LUSC	TCGA	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1111
p.A4747D	TCGA-78-8640	LUAD	TCGA	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.1667
p.T1908A	TCGA-85-6560	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2222
p.S1970G	TCGA-85-8580	LUSC	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.0556
p.T4376S	TCGA-85-A5B5	LUSC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.6005
p.T4376S	TCGA-BS-A0V8	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.6005
p.S4805C	TCGA-86-6851	LUAD	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0833
p.A3147G	TCGA-86-8279	LUAD	TCGA	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	TCGA-86-8279	LUAD	TCGA	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	SIDM00313	Hodgkin's Lymphoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	SIDM00313	Hodgkin's Lymphoma	GDSC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	SIDM01058	B-Cell Non-Hodgkin's Lymphoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	SIDM01058	B-Cell Non-Hodgkin's Lymphoma	GDSC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	SIDM00736	Non-Cancerous	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	SIDM00736	Non-Cancerous	GDSC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	SIDM01592	Breast Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	SIDM01592	Breast Carcinoma	GDSC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	L-1236	haematopoietic and lymphoid tissue	COSMIC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	L-1236	haematopoietic and lymphoid tissue	COSMIC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.A3147G	GRANTA-519	haematopoietic and lymphoid tissue	COSMIC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147G	GRANTA-519	haematopoietic and lymphoid tissue	COSMIC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.G4600D	TCGA-86-8673	LUAD	TCGA	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.25
p.G4600D	TCGA-B5-A3FC	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.25
p.P1490T	TCGA-86-A4JF	LUAD	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1111
p.T2024N	TCGA-90-7769	LUSC	TCGA	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.25
p.T1690I	TCGA-91-6848	LUAD	TCGA	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.7078
p.S4318Y	TCGA-91-6848	LUAD	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318Y	TCGA-91-6848	LUAD	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.E968D	TCGA-91-8499	LUAD	TCGA	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.1111
p.T3674N	TCGA-95-7567	LUAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.0833
p.T3728I	TCGA-96-8170	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.0833
p.T4654N	TCGA-97-7554	LUAD	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation altering degron motif	0.7055
p.V4365L	TCGA-98-A538	LUSC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1944
p.V4365L	TCGA-98-A538	LUSC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.0556
p.S2985C	TCGA-98-A53I	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.643
p.P2039S	TCGA-A1-A0SN	BRCA	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.6752
p.P2039S	TCGA-F4-6703	COAD	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.6752
p.C1507G	TCGA-A1-A0SO	BRCA	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1944
p.T3682M	TCGA-A2-A0SV	BRCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.T3682M	OCI-AML2	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.T3682M	MN-60	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.T3682M	GI-ME-N	autonomic ganglia	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.A2565T	TCGA-A5-A0G1	UCEC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.0833
p.S2469N	TCGA-A5-A0G2	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.1389
p.P2567S	TCGA-A5-A0G2	UCEC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1389
p.S2816N	TCGA-A5-A0G2	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.0833
p.T3527M	TCGA-A5-A0G2	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7423
p.S3726I	TCGA-A5-A0G2	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1389
p.A3200T	TCGA-A5-A0GA	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.3056
p.R1506Q	TCGA-A5-A0GI	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.2222
p.T4312A	TCGA-A5-A0GP	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.7139
p.A4747V	TCGA-A5-A1OF	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.1667
p.T1702M	TCGA-A5-A2K7	UCEC	TCGA	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.0556
p.A2981T	TCGA-A6-2686	COAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2778
p.T1675M	TCGA-A6-5657	COAD	TCGA	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.6312
p.V2574I	TCGA-A6-5661	COAD	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7076
p.S3027N	TCGA-A6-6781	COAD	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7069
p.S3027N	SIDM00660	Colorectal Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7069
p.S3027N	ACH-000985	Colon/Colorectal Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7069
p.S3027N	LS-411N	large intestine	COSMIC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7069
p.T3886M	TCGA-A6-A566	COAD	TCGA	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1667
p.T3886M	DO225077	BRCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1667
p.A2618T	TCGA-A8-A09Z	BRCA	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.1667
p.A2618T	TCGA-BR-8487	STAD	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.1667
p.A2037V	TCGA-AA-3492	COAD	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.5825
p.P4244L	TCGA-AA-3492	COAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.7582
p.P4244L	SIDM01043	Other Sarcomas	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.7582
p.A3496T	TCGA-AA-3672	COAD	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.A3146P	TCGA-AA-3848	COAD	TCGA	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.2222
p.A3146P	TCGA-AA-3848	COAD	TCGA	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.3056
p.A4375T	TCGA-AB-2931	LAML	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7139
p.A4375T	TCGA-AP-A056	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7139
p.S3488C	TCGA-AC-A5XS	BRCA	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.1111
p.V3274A	TCGA-AD-5900	COAD	TCGA	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.5825
p.V3274A	SIDM00842	Colorectal Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.5825
p.V3274A	SIDM00094	Kidney Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.5825
p.V3274A	COLO-320-HSR	large intestine	COSMIC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.5825
p.V3274A	SN12C	kidney	COSMIC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.5825
p.P4605S	TCGA-AD-5900	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.1111
p.A4404T	TCGA-AD-6964	COAD	TCGA	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.25
p.A4404T	TCGA-AD-6964	COAD	TCGA	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.2778
p.P1897S	TCGA-AJ-A23O	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.6752
p.P1644L	TCGA-AJ-A2QO	UCEC	TCGA	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7582
p.T2141M	TCGA-AJ-A3BH	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.1111
p.T4254I	TCGA-AJ-A3EK	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1389
p.E2820K	TCGA-AJ-A3EL	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1944
p.T3955M	TCGA-AJ-A3EL	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3963:3970	Mutation rewiring degron network	0.1111
p.K1952R	TCGA-AJ-A3OK	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation substituting flanking lysine	0.1667
p.T1974K	TCGA-AJ-A3OK	UCEC	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1667
p.T1974K	TCGA-L7-A6VZ	ESCA	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1667
p.P1975S	TCGA-AJ-A3OK	UCEC	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1944
p.T3002A	TCGA-AJ-A3OK	UCEC	TCGA	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation altering degron motif	0.7139
p.T4806M	TCGA-AJ-A3TW	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00305	Ovarian Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00565	Oral Cavity Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00064	Hepatocellular Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00975	Melanoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00192	Colorectal Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM01463	Endometrial Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00167	Head and Neck Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM00170	Head and Neck Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.T4806M	SIDM01394	Kidney Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.A4257T	TCGA-AJ-A5DW	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.0556
p.A3142V	TCGA-AP-A051	UCEC	TCGA	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation altering degron motif	0.5825
p.A3147T	TCGA-AP-A051	UCEC	TCGA	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.25
p.A3147T	TCGA-AP-A051	UCEC	TCGA	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2778
p.T3049P	TCGA-AP-A056	UCEC	TCGA	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1667
p.T3049P	TCGA-AP-A056	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.2222
p.T4768A	TCGA-AP-A056	UCEC	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation altering degron motif	0.7139
p.A3428S	TCGA-AP-A059	UCEC	TCGA	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.6477
p.T2576I	TCGA-AP-A0LM	UCEC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7078
p.V3205F	TCGA-AP-A0LM	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.1667
p.E4077K	TCGA-AP-A0LM	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.E4077K	TCGA-EI-6917	READ	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.L1653P	TCGA-AP-A1DK	UCEC	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.6471
p.P4407T	TCGA-AP-A1DM	UCEC	TCGA	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7031
p.R1875C	TCGA-AP-A1DV	UCEC	TCGA	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.1944
p.A4802T	TCGA-AP-A1DV	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.1667
p.A4432V	TCGA-AX-A05Z	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.A4432V	TCGA-UY-A8OD	BLCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.P1901L	TCGA-AX-A060	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7582
p.H2575P	TCGA-AX-A06F	UCEC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.6583
p.S4805Y	TCGA-AX-A0J0	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0833
p.A4797V	TCGA-AX-A0J1	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.3056
p.T1676M	TCGA-AX-A1C4	UCEC	TCGA	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.7423
p.P3016L	TCGA-AX-A1C9	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1111
p.P3016L	TCGA-AZ-6599	COAD	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1111
p.A4742S	TCGA-AX-A1CE	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.3056
p.R1661I	TCGA-AX-A2HC	UCEC	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.1111
p.T3396M	TCGA-AX-A2HG	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.V4345A	TCGA-AX-A3FT	UCEC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.S4674N	TCGA-AX-A3G9	UCEC	TCGA	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.2222
p.S4674N	TCGA-AX-A3G9	UCEC	TCGA	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.25
p.T3867A	TCGA-AZ-4315	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation altering degron motif	0.7139
p.T4829P	TCGA-AZ-4315	COAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.0833
p.T4835M	TCGA-AZ-6601	COAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.25
p.T3199M	TCGA-B5-A0JV	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation altering degron motif	0.7423
p.T2827A	TCGA-B5-A11E	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation altering degron motif	0.7139
p.T1894M	TCGA-B5-A11H	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.25
p.T1894M	TCGA-B5-A11H	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.3056
p.T1894M	TCGA-B5-A11H	UCEC	TCGA	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.1111
p.T1492M	TCGA-B5-A11X	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1667
p.A4257S	TCGA-B5-A1MR	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.0556
p.S4377R	TCGA-B5-A1MR	UCEC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7427
p.P4082S	TCGA-B5-A1MX	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.6752
p.G3526V	TCGA-B5-A3FA	UCEC	TCGA	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6421
p.G4576S	TCGA-B5-A3FA	UCEC	TCGA	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.2778
p.V2608L	TCGA-B5-A3FC	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation altering degron motif	0.6765
p.T4803I	TCGA-B5-A3FC	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.1389
p.T4388M	TCGA-BB-4223	HNSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6312
p.T4388M	TCGA-CR-7373	HNSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6312
p.T1767M	TCGA-BB-4228	HNSC	TCGA	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.1944
p.T1767M	SIDM01951	Colorectal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.1944
p.R4095K	TCGA-BF-A5EO	SKCM	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.0833
p.L3025P	TCGA-BG-A221	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.6471
p.S3492F	TCGA-BH-A0H7	BRCA	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.2222
p.T3874K	TCGA-BH-A42V	BRCA	TCGA	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.3056
p.T3874K	TCGA-BH-A42V	BRCA	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.V1980I	TCGA-BJ-A0ZB	THCA	TCGA	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation altering degron motif	0.5965
p.T2445M	TCGA-BK-A6W3	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.0556
p.T2445M	TCGA-D5-6928	COAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.0556
p.T4555A	TCGA-BK-A6W3	UCEC	TCGA	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2222
p.T4555A	SIDM00238	Ovarian Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2222
p.T4555A	ACH-000947	Ovarian Cancer	CCLE	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2222
p.T4555A	OVK-18	ovary	COSMIC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2222
p.P1910T	TCGA-BR-4362	STAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.1667
p.T4379P	TCGA-BR-A4J8	STAD	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7031
p.T1903M	TCGA-BS-A0TG	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.6312
p.T1903M	SIDM00672	Hepatocellular Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.6312
p.T1903M	SIDM00697	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.6312
p.W3890R	TCGA-C4-A0EZ	BLCA	TCGA	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0556
p.P3388L	TCGA-C5-A8XJ	CESC	TCGA	MATPSSS	DEG_SCF_FBW7_1	3374:3380	Mutation rewiring degron network	0.1111
p.P3388L	TCGA-C5-A8XJ	CESC	TCGA	PSSST	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1389
p.S2127N	TCGA-CC-5264	LIHC	TCGA	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.2222
p.S2127N	TCGA-CC-5264	LIHC	TCGA	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.25
p.G2031V	TCGA-CD-A4MG	STAD	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.1944
p.G2031V	TCGA-CD-A4MG	STAD	TCGA	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.0556
p.T4580I	TCGA-CF-A3MH	BLCA	TCGA	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.8189
p.T2028S	TCGA-CJ-4902	KIRC	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.1111
p.T2028S	TCGA-CJ-4902	KIRC	TCGA	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.1389
p.T2056N	TCGA-CM-4746	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.3056
p.T3680M	TCGA-CM-6162	COAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680M	TCGA-DU-6392	LGG	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680M	SIDM00602	Gastric Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.P4087L	TCGA-CM-6162	COAD	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.3056
p.R4219S	TCGA-CN-4727	HNSC	TCGA	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.0556
p.A4567D	TCGA-CN-5370	HNSC	TCGA	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2222
p.T4368M	TCGA-CN-6021	HNSC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.T4368M	TCGA-CN-6021	HNSC	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1389
p.T4368M	SIDM00499	Prostate Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.T4368M	SIDM00499	Prostate Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1389
p.T4368M	22RV1	prostate	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.T4368M	22RV1	prostate	COSMIC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1389
p.R4904P	TCGA-CN-A63W	HNSC	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1667
p.T2167N	TCGA-CN-A641	HNSC	TCGA	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.2778
p.S1893Y	TCGA-CV-6935	HNSC	TCGA	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation altering degron motif	0.712
p.G4843E	TCGA-CV-7263	HNSC	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.6087
p.A1895T	TCGA-CV-7568	HNSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2778
p.A1895T	TCGA-CV-7568	HNSC	TCGA	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.2778
p.A1895T	TCGA-CV-7568	HNSC	TCGA	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0833
p.P2596T	TCGA-CV-A45Z	HNSC	TCGA	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.7031
p.A3428T	TCGA-D1-A174	UCEC	TCGA	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.6028
p.P2157H	TCGA-D1-A17H	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.3056
p.P2157H	TCGA-D1-A17H	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.2222
p.S4383Y	TCGA-D3-A1Q1	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6009
p.T4829I	TCGA-D3-A2JE	SKCM	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.0833
p.L1653R	TCGA-D3-A8GM	SKCM	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.8428
p.G4083E	TCGA-D9-A6EA	SKCM	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.6087
p.A3841V	TCGA-D9-A6EC	SKCM	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.0833
p.A3841V	TCGA-D9-A6EC	SKCM	TCGA	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1667
p.A3841V	TCGA-D9-A6EC	SKCM	TCGA	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.3056
p.P3525Q	TCGA-DA-A1I1	SKCM	TCGA	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7035
p.A3700T	TCGA-DA-A1I7	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.0556
p.A3700T	TCGA-EE-A2GN	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.0556
p.P4386S	TCGA-DA-A1I8	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6752
p.A4346T	TCGA-DB-A64X	LGG	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1389
p.S3061Y	TCGA-DD-A4NG	LIHC	TCGA	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation blocking phosphorylation signal	0.6667
p.T1510K	TCGA-DD-AADC	LIHC	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1111
p.H3832Q	TCGA-DD-AADY	LIHC	TCGA	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.647
p.S3207N	TCGA-DF-A2KU	UCEC	TCGA	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation blocking phosphorylation signal	0.5556
p.R1931I	TCGA-DF-A2KV	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1389
p.S2568F	TCGA-DG-A2KK	CESC	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1667
p.P3507A	TCGA-DG-A2KK	CESC	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.1389
p.I4351M	TCGA-DG-A2KK	CESC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.2778
p.T3310N	TCGA-DH-A7UU	LGG	TCGA	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation altering degron motif	0.7055
p.S4349C	TCGA-DI-A1BU	UCEC	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6667
p.T4768P	TCGA-DK-A6AW	BLCA	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation altering degron motif	0.7031
p.T2042N	TCGA-DK-A6B5	BLCA	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7055
p.S2258N	TCGA-DK-AA6R	BLCA	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.0556
p.W3890C	TCGA-DR-A0ZM	CESC	TCGA	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0556
p.P2430L	TCGA-DU-6392	LGG	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.7582
p.T3868S	TCGA-DU-A7T6	LGG	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation altering degron motif	0.6005
p.P3020L	TCGA-DX-A1KX	SARC	TCGA	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.2222
p.P1633L	TCGA-DX-AB2E	SARC	TCGA	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.0556
p.G3130R	TCGA-DX-AB2E	SARC	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2778
p.S952C	TCGA-E2-A1LG	BRCA	TCGA	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.25
p.T4624I	TCGA-E5-A4U1	BLCA	TCGA	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.3056
p.E1464K	TCGA-E6-A1LX	UCEC	TCGA	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.1389
p.E1464K	TCGA-EO-A3AV	UCEC	TCGA	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.1389
p.E1464K	TCGA-KK-A59V	PRAD	TCGA	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.1389
p.T4645A	TCGA-E6-A1LX	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1667
p.S4072G	TCGA-E7-A85H	BLCA	TCGA	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.0556
p.Q2682H	TCGA-E9-A1ND	BRCA	TCGA	MATPSSS	DEG_SCF_FBW7_1	2674:2680	Mutation rewiring degron network	0.2778
p.Q2682H	TCGA-E9-A1ND	BRCA	TCGA	PSSST	DEG_SPOP_SBC_1	2677:2681	Mutation rewiring degron network	0.3056
p.Q1632H	TCGA-E9-A5UO	BRCA	TCGA	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.0833
p.A1698T	TCGA-EB-A41A	SKCM	TCGA	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.1667
p.E1655K	TCGA-EB-A553	SKCM	TCGA	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.2778
p.E1655K	TCGA-EB-A553	SKCM	TCGA	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1389
p.T3703I	TCGA-EB-A5SE	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.0833
p.P4344L	TCGA-EB-A5UM	SKCM	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.P4344L	TCGA-WE-A8K5	SKCM	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.R3046M	TCGA-EB-A6QY	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.25
p.R3046M	TCGA-EB-A6QY	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1389
p.A3846V	TCGA-EE-A181	SKCM	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846V	TCGA-EE-A181	SKCM	TCGA	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.G2988V	TCGA-EE-A29D	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.6421
p.S3908F	TCGA-EE-A29D	SKCM	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.0556
p.S4318F	TCGA-EE-A29E	SKCM	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318F	TCGA-EE-A29E	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.P3100Q	TCGA-EE-A29G	SKCM	TCGA	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.7035
p.G2031E	TCGA-EE-A29M	SKCM	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.1944
p.G2031E	TCGA-EE-A29M	SKCM	TCGA	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.0556
p.I1906M	TCGA-EE-A2GN	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2778
p.G1667S	TCGA-EE-A2MN	SKCM	TCGA	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.1389
p.H4779N	TCGA-EE-A2MN	SKCM	TCGA	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.0833
p.T4408M	TCGA-EE-A2MT	SKCM	TCGA	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.6312
p.T4408M	SNU-1040	large intestine	COSMIC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.6312
p.G3707E	TCGA-EE-A3AE	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1944
p.R4303K	TCGA-EE-A3AG	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303K	TCGA-EE-A3AG	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.R4303K	TCGA-GN-A4U8	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303K	TCGA-GN-A4U8	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.R4303K	TCGA-YG-AA3N	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303K	TCGA-YG-AA3N	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.V3889M	TCGA-EE-A3J5	SKCM	TCGA	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0833
p.A4315T	TCGA-EE-A3JD	SKCM	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.1111
p.A4315T	TCGA-EE-A3JD	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.3056
p.S4607F	TCGA-EE-A3JD	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.0556
p.P3353Q	TCGA-EI-7002	READ	TCGA	VLTTT	DEG_SPOP_SBC_1	3361:3365	Mutation rewiring degron network	0.1111
p.S3854Y	TCGA-EK-A3GK	CESC	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.6009
p.S4383F	TCGA-EK-A3GK	CESC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6871
p.T4368K	TCGA-EL-A3ZR	THCA	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.T4368K	TCGA-EL-A3ZR	THCA	TCGA	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1389
p.V4908L	TCGA-EO-A22R	UCEC	TCGA	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0556
p.G948S	TCGA-EO-A22U	UCEC	TCGA	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.1389
p.D1881N	TCGA-EO-A22U	UCEC	TCGA	DDYSHCP	CBL_PTK	1880:1886	Mutation altering degron motif	0.5821
p.H3832R	TCGA-EO-A22X	UCEC	TCGA	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.7133
p.T2720S	TCGA-EO-A3AV	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	2718:2722	Mutation altering degron motif	0.6005
p.A4233T	TCGA-EO-A3B0	UCEC	TCGA	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6028
p.A4233T	TCGA-EO-A3B0	UCEC	TCGA	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.6028
p.P4353S	TCGA-ER-A193	SKCM	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6752
p.P4700L	TCGA-EW-A1PB	BRCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation altering degron motif	0.7582
p.T3677A	TCGA-EY-A1GD	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1667
p.S3987T	TCGA-EY-A1GK	UCEC	TCGA	AATSS	DEG_SPOP_SBC_1	3984:3988	Mutation altering degron motif	0.6005
p.P3296S	TCGA-EY-A215	UCEC	TCGA	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.6752
p.T3283M	TCGA-EY-A549	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation altering degron motif	0.7423
p.A4291V	TCGA-F1-6177	STAD	TCGA	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation altering degron motif	0.5825
p.P4325A	TCGA-F1-6177	STAD	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7503
p.M4239T	TCGA-F4-6856	COAD	TCGA	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2222
p.M4239T	TCGA-F4-6856	COAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.3056
p.M4239T	TCGA-F4-6856	COAD	TCGA	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.25
p.M4239T	22RV1	prostate	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2222
p.M4239T	22RV1	prostate	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.3056
p.M4239T	22RV1	prostate	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.25
p.M4239T	SNU-175	large intestine	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2222
p.M4239T	SNU-175	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.3056
p.M4239T	SNU-175	large intestine	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.25
p.A1914V	TCGA-F5-6813	READ	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.0556
p.T4307A	TCGA-FD-A3N6	BLCA	TCGA	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation blocking phosphorylation signal	0.5833
p.T4307A	TCGA-FD-A3N6	BLCA	TCGA	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6944
p.T4307A	SIDM00158	Glioblastoma	GDSC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation blocking phosphorylation signal	0.5833
p.T4307A	SIDM00158	Glioblastoma	GDSC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6944
p.T2725A	TCGA-FI-A2D5	UCEC	TCGA	VLTTT	DEG_SPOP_SBC_1	2718:2722	Mutation rewiring degron network	0.25
p.T2725A	TCGA-FI-A2D5	UCEC	TCGA	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation rewiring degron network	0.2778
p.N3405D	TCGA-FI-A2D5	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.3056
p.P3712L	TCGA-FI-A2EU	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.6471
p.P4851L	TCGA-FP-7829	STAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.P4851L	TCGA-HF-7132	STAD	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.P4851L	SIDM00780	Colorectal Carcinoma	GDSC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.P4851L	ACH-000967	Colon/Colorectal Cancer	CCLE	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.P3129L	TCGA-FR-A3YN	SKCM	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.3056
p.P3129L	TCGA-VQ-A91D	STAD	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.3056
p.P3129L	SIDM00003	Melanoma	GDSC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.3056
p.P3129L	M14	skin	COSMIC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.3056
p.P4338S	TCGA-FR-A7U9	SKCM	TCGA	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.0556
p.I3134F	TCGA-FS-A1YW	SKCM	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1667
p.I3134F	TCGA-FS-A1YW	SKCM	TCGA	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.1389
p.T1502I	TCGA-FS-A1ZF	SKCM	TCGA	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation altering degron motif	0.7078
p.R4730M	TCGA-FS-A1ZG	SKCM	TCGA	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation rewiring degron network	0.0833
p.R4730M	TCGA-FS-A1ZG	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.25
p.R4730M	TCGA-FS-A1ZG	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.1389
p.G3526R	TCGA-FW-A3R5	SKCM	TCGA	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6457
p.G3526R	SIDM00392	Melanoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6457
p.G3526R	ACH-000810	Skin Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6457
p.G3526R	SK-MEL-30	skin	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6457
p.G4644E	TCGA-FW-A3TV	SKCM	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1389
p.S2569F	TCGA-G2-AA3C	BLCA	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1944
p.S2569F	TCGA-G2-AA3C	BLCA	TCGA	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.0556
p.S2651C	TCGA-G2-AA3C	BLCA	TCGA	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0556
p.T3115M	TCGA-G4-6320	COAD	TCGA	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1389
p.P4643Q	TCGA-G9-6342	PRAD	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1111
p.R2838S	TCGA-G9-7525	PRAD	TCGA	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.0833
p.W1905C	TCGA-GD-A3OP	BLCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.S3402F	TCGA-GM-A2D9	BRCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.2222
p.S3437F	TCGA-GN-A8LK	SKCM	TCGA	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.1667
p.G4226S	TCGA-GS-A9TZ	DLBC	TCGA	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.25
p.G4226S	TCGA-GS-A9TZ	DLBC	TCGA	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.1667
p.P2825T	TCGA-HE-7128	KIRP	TCGA	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation altering degron motif	0.7031
p.V3865M	TCGA-HT-7480	LGG	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation altering degron motif	0.7208
p.T2452M	TCGA-HT-8564	LGG	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.25
p.W2991R	TCGA-HU-A4GX	STAD	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.3056
p.W2991R	TCGA-HU-A4GX	STAD	TCGA	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1111
p.P4344H	TCGA-HU-A4H3	STAD	TCGA	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.A2046V	TCGA-HU-A4HD	STAD	TCGA	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2222
p.A2046V	TCGA-HU-A4HD	STAD	TCGA	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1944
p.S2689P	TCGA-IB-7651	PAAD	TCGA	MATPSSS	DEG_SCF_FBW7_1	2674:2680	Mutation rewiring degron network	0.0833
p.S2689P	TCGA-IB-7651	PAAD	TCGA	PSSST	DEG_SPOP_SBC_1	2677:2681	Mutation rewiring degron network	0.1111
p.A2618S	TCGA-IC-A6RF	ESCA	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.1667
p.T1949N	TCGA-IQ-A6SG	HNSC	TCGA	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1389
p.S4726F	TCGA-JX-A3Q0	CESC	TCGA	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation altering degron motif	0.7982
p.E4785Q	TCGA-KQ-A41Q	BLCA	TCGA	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.1389
p.A4717T	TCGA-L5-A891	ESCA	TCGA	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation altering degron motif	0.7139
p.R51Q	TCGA-L5-A8NN	ESCA	TCGA	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51Q	TCGA-W5-AA2Z	CHOL	TCGA	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.K3695E	TCGA-LA-A7SW	LUSC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.K3695E	SIDM00499	Prostate Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.K3695E	SIDM00555	Glioblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.K3695E	SIDM00095	Glioblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.K3695E	SNB75	central nervous system	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.K3695E	KS-1	central nervous system	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation substituting flanking lysine	0.3056
p.S4839Y	TCGA-LN-A9FP	ESCA	TCGA	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.6009
p.S4633C	TCGA-NC-A5HF	LUSC	TCGA	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.2222
p.A3860V	TCGA-NH-A5IV	COAD	TCGA	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3860V	TCGA-NH-A5IV	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.T2578I	TCGA-NJ-A4YP	LUAD	TCGA	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7078
p.S2122C	TCGA-OL-A5DA	BRCA	TCGA	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation altering degron motif	0.643
p.S2122C	TCGA-OL-A5DA	BRCA	TCGA	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation altering degron motif	0.7541
p.S2978G	TCGA-P4-A5E7	KIRP	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1944
p.P4232L	TCGA-QC-A6FX	SARC	TCGA	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7582
p.P4232L	TCGA-QC-A6FX	SARC	TCGA	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7582
p.S2267F	TCGA-QK-A6VC	HNSC	TCGA	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.3056
p.A4649T	TCGA-QR-A70G	PCPG	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649T	TCGA-YH-A8SY	PAAD	TCGA	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649T	SIDM00683	Prostate Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649T	SIDM00783	Colorectal Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649T	ACH-000971	Colon/Colorectal Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.E1752K	TCGA-RP-A693	SKCM	TCGA	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.1667
p.G3911E	TCGA-T3-A92M	HNSC	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1389
p.P3495Q	TCGA-UC-A7PG	CESC	TCGA	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.3056
p.G3291S	TCGA-UD-AAC1	MESO	TCGA	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.2778
p.G3291S	TCGA-UD-AAC1	MESO	TCGA	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1111
p.T2619N	TCGA-VQ-A8PJ	STAD	TCGA	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.1389
p.G3911R	TCGA-W3-A824	SKCM	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1389
p.G4245E	TCGA-W3-A828	SKCM	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.6087
p.V1688M	TCGA-W3-AA1V	SKCM	TCGA	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.7208
p.T1911S	TCGA-W5-AA39	CHOL	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation blocking phosphorylation signal	0.5833
p.L4392F	TCGA-XE-A8H5	TGCT	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.25
p.L4392F	TCGA-XE-A8H5	TGCT	TCGA	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.1667
p.A4550T	TCGA-XK-AAIW	PRAD	TCGA	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.0833
p.S4433P	TCGA-YF-AA3M	BLCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1389
p.S4669F	TCGA-YG-AA3N	SKCM	TCGA	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation altering degron motif	0.6871
p.S4669F	TCGA-YG-AA3N	SKCM	TCGA	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation altering degron motif	0.7982
p.P3052S	TCGA-Z2-A8RT	SKCM	TCGA	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.0833
p.P3052S	TCGA-Z2-A8RT	SKCM	TCGA	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.S4384C	TCGA-ZF-AA4R	BLCA	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.643
p.S3930F	TCGA-ZF-AA4X	BLCA	TCGA	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.3056
p.S3930F	TCGA-ZF-AA4X	BLCA	TCGA	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1111
p.S3930F	TCGA-ZF-AA4X	BLCA	TCGA	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.2222
p.V4593M	TCGA-ZG-A9N3	PRAD	TCGA	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation altering degron motif	0.7208
p.T3118M	DO49265	ALL	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2222
p.T3118M	DO8159	COAD	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2222
p.V4326F	DO48371	BLCA	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7068
p.V4326F	DO229221	THCA	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7068
p.V4562A	DO48402	BLCA	ICGC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation altering degron motif	0.6936
p.S4436P	DO51952	BLCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.2222
p.M3822R	DO51907	BLCA	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.0833
p.S2654C	DO51883	BLCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.1389
p.S2572F	DO51883	BLCA	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.2778
p.S2572F	DO51883	BLCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1389
p.T2045N	DO48551	BLCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.25
p.T2045N	DO48551	BLCA	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1667
p.T4771P	DO48566	BLCA	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.T4627I	DO44061	BLCA	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation altering degron motif	0.7078
p.E4788Q	DO223591	BLCA	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.2222
p.S3187F	DO219046	BLCA	ICGC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.1111
p.A4435V	DO219039	BLCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1944
p.A4435V	DO40884	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1944
p.S4075G	DO219018	BLCA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1389
p.S2261N	DO219006	BLCA	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1389
p.S3933F	DO219091	BLCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation altering degron motif	0.7982
p.S4387C	DO219083	BLCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7541
p.P3690L	DO457	BLCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P3690L	DO29248	OV	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.P3690L	DO42793	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7582
p.T4310A	DO575	BLCA	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.7139
p.T4583I	DO791	BLCA	ICGC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.7078
p.W1908C	DO761	BLCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2222
p.T4391M	DO225198	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.2778
p.T4391M	DO225198	BRCA	ICGC	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.1389
p.T4391M	DO16093	HNSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.2778
p.T4391M	DO16093	HNSC	ICGC	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.1389
p.T4391M	DO15607	HNSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.2778
p.T4391M	DO15607	HNSC	ICGC	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.1389
p.A2597V	DO225276	BRCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6936
p.A2597V	DO224802	BRCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6936
p.R3888S	DO225276	BRCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1111
p.R3888S	DO224802	BRCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1111
p.T4307N	DO224709	BRCA	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation blocking phosphorylation signal	0.5833
p.T4307N	DO224709	BRCA	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6944
p.A4308V	DO224709	BRCA	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1111
p.A4308V	DO224709	BRCA	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.2778
p.E3707A	DO224957	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1944
p.T3685M	DO1914	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7423
p.S3495F	DO1984	BRCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.3056
p.S3491C	DO50023	BRCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.1944
p.T3877K	DO44129	BRCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation altering degron motif	0.7306
p.S2125C	DO44121	BRCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.2778
p.S2125C	DO44121	BRCA	ICGC	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.3056
p.Q1635H	DO44105	BRCA	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.0833
p.T3398N	DO2665	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1111
p.P4703L	DO4695	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation altering degron motif	0.7582
p.C1510G	DO2020	BRCA	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1111
p.S3405F	DO4810	BRCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.3056
p.Q2685H	DO5780	BRCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	2674:2680	Mutation rewiring degron network	0.1944
p.Q2685H	DO5780	BRCA	ICGC	PSSST	DEG_SPOP_SBC_1	2677:2681	Mutation rewiring degron network	0.2222
p.T4344I	DO5905	BRCA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.P2042S	DO4299	BRCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.6752
p.P2042S	DO9908	COAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.6752
p.S955C	DO4018	BRCA	ICGC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation altering degron motif	0.7541
p.A2621T	DO5521	BRCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.0833
p.A2621T	DO47867	STAD	ICGC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.0833
p.S4758C	DO5500	BRCA	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1111
p.S4758C	DO44456	HNSC	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1111
p.S4758C	DO220239	SARC	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1111
p.P1640L	DO222364	BTCA	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.1667
p.P1640L	DO222364	BTCA	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.2222
p.T1625I	DO222364	BTCA	ICGC	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.2778
p.I4252T	DO222427	BTCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.S48L	DO222625	BTCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.8778
p.P3675H	DO49894	CESC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1111
p.S4729F	DO51607	CESC	ICGC	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation rewiring degron network	0.1111
p.S4729F	DO51607	CESC	ICGC	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.2778
p.S4729F	DO51607	CESC	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.1111
p.P3498Q	DO51615	CESC	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7035
p.I4354M	DO51595	CESC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.7618
p.P3510A	DO51595	CESC	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.0556
p.S2571F	DO51595	CESC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.25
p.S2571F	DO51595	CESC	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.S4386F	DO49964	CESC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7982
p.S3857Y	DO49964	CESC	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.3056
p.S3857Y	DO49964	CESC	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1111
p.P3391L	DO49902	CESC	ICGC	PSSST	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.0556
p.A1761T	DO223732	CESC	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7139
p.S4316I	DO52707	CLLE	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.5833
p.S4316I	DO52707	CLLE	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.7222
p.T4375M	DO6472	CLLE	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7423
p.E1467K	DO6585	CLLE	ICGC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.0556
p.E1467K	DO51346	PRAD	ICGC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.0556
p.E1467K	DO41020	UCEC	ICGC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.0556
p.E1467K	DO52412	UCEC	ICGC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.0556
p.T4838M	DO8119	COAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.7423
p.M4242T	DO9114	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.7423
p.A2697T	DO49095	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.0833
p.A2697T	DO42713	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.0833
p.A3863V	DO49095	COAD	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation blocking phosphorylation signal	0.5833
p.A3863V	DO49095	COAD	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation blocking phosphorylation signal	0.7222
p.A3499T	DO9010	COAD	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.T1678M	DO10459	COAD	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.7423
p.T3889M	DO44092	COAD	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0833
p.P3019L	DO10606	COAD	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1944
p.P3019L	DO43098	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1944
p.T2448M	DO7776	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.1389
p.T2448M	DO50076	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.1389
p.A2984T	DO7828	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7139
p.T2059N	DO7882	COAD	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.2222
p.T3870A	DO8842	COAD	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.T3870A	DO8842	COAD	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.3056
p.T4832P	DO8842	COAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.V2577I	DO8634	COAD	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7076
p.A3149P	DO9740	COAD	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.3056
p.A3149P	DO9740	COAD	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2222
p.T3683M	DO8479	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7423
p.T3683M	DO48270	ESCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7423
p.T3683M	DO22237	LGG	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.7423
p.P4090L	DO8479	COAD	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.2222
p.S3030N	DO8447	COAD	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation blocking phosphorylation signal	0.7222
p.S3030N	DO8447	COAD	ICGC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation blocking phosphorylation signal	0.5278
p.V3277A	DO8514	COAD	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation altering degron motif	0.6936
p.P4247L	DO8224	COAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.7582
p.A2040V	DO8224	COAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.6936
p.A4407T	DO8360	COAD	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7139
p.A3092T	DO230309	COCA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.2222
p.T3871I	DO230347	COCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.2222
p.T3871I	DO230347	COCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.2778
p.T1765M	DO230343	COCA	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.25
p.A4289T	DO227844	COCA	ICGC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation altering degron motif	0.7139
p.G2591R	DO227975	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO227975	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.G2591R	DO224761	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO224761	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.G2591R	DO51019	LAML	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO51019	LAML	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.G2591R	DO229061	LICA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO229061	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.G2591R	DO229006	LICA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO229006	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.G2591R	DO229259	THCA	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.2778
p.G2591R	DO229259	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1111
p.T1906M	DO227976	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2778
p.T1906M	DO233855	GACA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2778
p.T1906M	DO42209	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.2778
p.T5286P	DO224668	COCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.25
p.T5286P	DO224668	COCA	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1389
p.T5286P	DO223150	ESCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.25
p.T5286P	DO223150	ESCA	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1389
p.T5286P	DO22382	LGG	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.25
p.T5286P	DO22382	LGG	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1389
p.M3125T	DO224721	COCA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.7423
p.M3125T	DO222752	COCA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.7423
p.M3125T	DO229010	COCA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.7423
p.M3125T	DO229013	COCA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.7423
p.M3125T	DO52370	LUSC	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.7423
p.L5293P	DO224744	COCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.0556
p.A3150V	DO222492	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.6936
p.A3150T	DO222755	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7139
p.A3150T	DO42673	UCEC	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7139
p.T1673N	DO222755	COCA	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.3056
p.R52H	DO222765	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.2222
p.T3287A	DO222809	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1667
p.T3287A	DO222809	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0833
p.T3287A	DO222809	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.2222
p.T3287A	DO229016	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1667
p.T3287A	DO229016	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0833
p.T3287A	DO229016	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.2222
p.T3287A	DO229003	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1667
p.T3287A	DO229003	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0833
p.T3287A	DO229003	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.2222
p.T3287A	DO229005	COCA	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1667
p.T3287A	DO229005	COCA	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0833
p.T3287A	DO229005	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.2222
p.P4443L	DO222826	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO229010	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO229013	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO229016	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO229003	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO229005	COCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.P4443L	DO46969	RECA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation altering degron motif	0.7582
p.T4411M	DO222839	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.T4411M	DO229347	LAML	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.T4411M	DO228947	LICA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.T4411M	DO229028	LICA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.T4411M	DO224551	LUSC	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.T4411M	DO38051	SKCM	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7423
p.E34G	DO229010	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.0556
p.E34G	DO229013	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.0556
p.E34G	DO229346	LAML	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.0556
p.E34G	DO230659	LAML	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.0556
p.R51W	DO229010	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51W	DO229013	COCA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51W	DO229346	LAML	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51W	DO52365	LUSC	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51W	DO231022	LUSC	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.R51W	DO231155	LUSC	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.V3912I	DO229010	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229013	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229016	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229003	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229005	COCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229346	LAML	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO218878	SKCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.V3912I	DO229221	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1667
p.T3154M	DO229010	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO229013	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO229016	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO229003	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO229005	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO233731	GACA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO229346	LAML	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.T3154M	DO52365	LUSC	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7423
p.S3503G	DO229010	COCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.S3503G	DO229013	COCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.S3503G	DO229016	COCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.S3503G	DO229003	COCA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.S3503G	DO229053	LICA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.T4709P	DO229010	COCA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229010	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.T4709P	DO229013	COCA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229013	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.T4709P	DO229016	COCA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229016	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.T4709P	DO229003	COCA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229003	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.T4709P	DO229005	COCA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229005	COCA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.T4709P	DO229346	LAML	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.7031
p.T4709P	DO229346	LAML	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.7031
p.A4407G	DO229010	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229013	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229016	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229003	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229005	COCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229346	LAML	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO229006	LICA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.A4407G	DO46969	RECA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.754
p.G4229S	DO219918	DLBC	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6993
p.G4229S	DO229227	THCA	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6993
p.T1633M	DO228696	EOPC	ICGC	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.0556
p.T4249M	DO50442	ESAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.2778
p.A4323V	DO234153	ESAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.6936
p.P4890L	DO234389	ESAD	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.2222
p.P4890L	DO220908	MELA	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.2222
p.S4899I	DO234285	ESAD	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.3056
p.T4630I	DO234286	ESAD	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.3056
p.R1509Q	DO48244	ESCA	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1389
p.R1509Q	DO41807	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1389
p.E3104Q	DO48228	ESCA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.3056
p.T3872A	DO223071	ESCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.25
p.T3872A	DO223071	ESCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.25
p.R2263K	DO222575	ESCA	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1944
p.T4094R	DO228618	GACA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO228805	GACA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO229024	LICA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO229053	LICA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO229006	LICA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO231007	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4094R	DO51470	PACA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1111
p.T4803A	DO233634	GACA	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.1389
p.M4802I	DO233634	GACA	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.1667
p.V1688A	DO233649	GACA	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.5825
p.S4357T	DO233705	GACA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.7116
p.Q1635P	DO233854	GACA	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.0833
p.A3007T	DO233903	GACA	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.2222
p.Q2999P	DO233900	GACA	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation altering degron motif	0.7035
p.E2998K	DO233900	GACA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1111
p.E2998K	DO233900	GACA	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.3056
p.T1932I	DO12556	GBM	ICGC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1667
p.T1899M	DO13845	GBM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7423
p.R4907H	DO12928	GBM	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.R4907H	DO26337	LUAD	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.R4907H	DO231495	THCA	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.R4907H	DO43907	UCEC	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.A4745T	DO10880	GBM	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation blocking phosphorylation signal	0.6667
p.A4769T	DO10880	GBM	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation altering degron motif	0.7139
p.T4371M	DO15847	HNSC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.G3691E	DO49033	HNSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.G3691E	DO26528	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.G3691E	DO222415	MELA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.3056
p.R4907P	DO49031	HNSC	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.G3914E	DO223269	HNSC	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.2222
p.T1952N	DO223267	HNSC	ICGC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation substituting flanking lysine	0.1667
p.T2170N	DO44436	HNSC	ICGC	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.1944
p.A1898T	DO14160	HNSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7139
p.S2270F	DO219056	HNSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation altering degron motif	0.7982
p.T1770M	DO15262	HNSC	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.1111
p.T1770M	DO49143	PACA	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.1111
p.G4846E	DO14398	HNSC	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.3056
p.R4222S	DO14258	HNSC	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.1389
p.R4222S	DO14258	HNSC	ICGC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.0556
p.S1896Y	DO15238	HNSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.S1896Y	DO15238	HNSC	ICGC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation rewiring degron network	0.25
p.S1896Y	DO15238	HNSC	ICGC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0556
p.A4570D	DO15126	HNSC	ICGC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.1111
p.A4570D	DO15126	HNSC	ICGC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.1389
p.P2599T	DO52064	HNSC	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.7031
p.A4431T	DO19208	KIRC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.0833
p.A4431T	DO38711	STAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.0833
p.T2031S	DO17693	KIRC	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.1944
p.T2031S	DO17693	KIRC	ICGC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.0556
p.S2981G	DO48479	KIRP	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2778
p.P2828T	DO20796	KIRP	ICGC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation altering degron motif	0.7031
p.A3834V	DO228007	LAML	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.6936
p.A3834V	DO231117	LAML	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.6936
p.P1892L	DO230659	LAML	ICGC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation altering degron motif	0.7582
p.P1892L	DO231140	LAML	ICGC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation altering degron motif	0.7582
p.P1892L	DO229047	LICA	ICGC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation altering degron motif	0.7582
p.P1892L	DO231049	LUSC	ICGC	PATSS	DEG_SPOP_SBC_1	1889:1893	Mutation altering degron motif	0.7582
p.V4348M	DO51032	LAML	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1944
p.V4348M	DO229033	LICA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1944
p.V4348M	DO229211	THCA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1944
p.V3493G	DO231147	LAML	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.25
p.T4715M	DO231140	LAML	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation rewiring degron network	0.1944
p.T4715M	DO231140	LAML	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation rewiring degron network	0.25
p.T4715M	DO231140	LAML	ICGC	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation rewiring degron network	0.2778
p.T4715M	DO231140	LAML	ICGC	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.1111
p.T4715M	DO229047	LICA	ICGC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation rewiring degron network	0.1944
p.T4715M	DO229047	LICA	ICGC	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation rewiring degron network	0.25
p.T4715M	DO229047	LICA	ICGC	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation rewiring degron network	0.2778
p.T4715M	DO229047	LICA	ICGC	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.1111
p.T4885A	DO231140	LAML	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.T4885A	DO229047	LICA	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.T4885A	DO231067	LUSC	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.A4378T	DO22074	LAML	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7139
p.A4378T	DO35442	PACA	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7139
p.A4378T	DO43971	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7139
p.T3313N	DO51812	LGG	ICGC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.3056
p.T3871S	DO51814	LGG	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.2222
p.T3871S	DO51814	LGG	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.2778
p.V3868M	DO22639	LGG	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation altering degron motif	0.7208
p.P2433L	DO22237	LGG	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.7582
p.V4903M	DO22237	LGG	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1944
p.V4903M	DO222327	STAD	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1944
p.T2455M	DO44623	LGG	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation altering degron motif	0.7423
p.A4349T	DO44570	LGG	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6667
p.S1639R	DO231967	LICA	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.1389
p.S1639R	DO231967	LICA	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1944
p.P2978T	DO228806	LICA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1944
p.A2731T	DO228835	LICA	ICGC	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7139
p.A2731D	DO228835	LICA	ICGC	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7793
p.P4232H	DO228835	LICA	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7694
p.P4232H	DO228835	LICA	ICGC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7694
p.V3978L	DO228948	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	3975:3979	Mutation altering degron motif	0.6765
p.A957S	DO228948	LICA	ICGC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation altering degron motif	0.7588
p.R1878L	DO228952	LICA	ICGC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.2778
p.R1509L	DO228952	LICA	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1389
p.A4652S	DO228952	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation altering degron motif	0.7588
p.M3265I	DO228986	LICA	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0833
p.A4892S	DO228986	LICA	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.2778
p.A4833S	DO229018	LICA	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1944
p.A44S	DO229018	LICA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.7588
p.A44S	DO229035	LICA	ICGC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.7588
p.S3883I	DO229018	LICA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.25
p.A2030S	DO229019	LICA	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.1667
p.A2030S	DO229019	LICA	ICGC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.0833
p.M2565I	DO229015	LICA	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.0833
p.A2011S	DO229025	LICA	ICGC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.1667
p.A3441S	DO229036	LICA	ICGC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.0556
p.W3694C	DO229045	LICA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.2222
p.T2041I	DO229047	LICA	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7078
p.T3135I	DO229052	LICA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1389
p.T3135I	DO229052	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.1667
p.R4653T	DO229052	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation altering degron motif	0.7876
p.S4636R	DO229052	LICA	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.1389
p.T3501S	DO229051	LICA	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.3056
p.A2621V	DO229057	LICA	ICGC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.0833
p.A4401T	DO229057	LICA	ICGC	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation altering degron motif	0.7139
p.K3063T	DO229062	LICA	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1667
p.T1679M	DO50812	LICA	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.7423
p.T1679M	DO42480	UCEC	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.7423
p.P1689Q	DO50767	LICA	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.7035
p.P4276S	DO50970	LICA	ICGC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.0833
p.T2132I	DO50970	LICA	ICGC	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.0833
p.T2132I	DO50970	LICA	ICGC	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.1111
p.T3714I	DO44802	LICA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7078
p.S2130N	DO23053	LIHC	ICGC	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.1389
p.S2130N	DO23053	LIHC	ICGC	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.1667
p.T4764M	DO48475	LIHC	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.2778
p.T4764M	DO26620	LUSC	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.2778
p.T4764M	DO46657	PAAD	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.2778
p.S3064Y	DO44885	LIHC	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1389
p.H3835Q	DO52251	LIHC	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.7582
p.T4737I	DO231700	LINC	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation altering degron motif	0.7078
p.G4448R	DO23490	LINC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.3056
p.V962L	DO45031	LINC	ICGC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.2778
p.S4701L	DO229244	LMS	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation altering degron motif	0.7667
p.P3526T	DO25659	LUAD	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7031
p.P2599S	DO24307	LUAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6752
p.T3677N	DO25564	LUAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1667
p.P3860T	DO24596	LUAD	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.P3860T	DO24596	LUAD	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.G1488V	DO24596	LUAD	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.0556
p.P4757L	DO25837	LUAD	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.0833
p.T3038I	DO25252	LUAD	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation substituting flanking lysine	0.1667
p.T4324N	DO25232	LUAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7055
p.T2581I	DO218943	LUAD	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation altering degron motif	0.7078
p.T2585N	DO218922	LUAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.1111
p.T2585N	DO218922	LUAD	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1389
p.T2585N	DO218922	LUAD	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.2778
p.T2585N	DO219209	LUSC	ICGC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation rewiring degron network	0.1111
p.T2585N	DO219209	LUSC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1389
p.T2585N	DO219209	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.2778
p.P2260H	DO218922	LUAD	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1111
p.A3150G	DO24140	LUAD	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.754
p.G2061A	DO24150	LUAD	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1667
p.L960I	DO23830	LUAD	ICGC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation altering degron motif	0.7174
p.T1693I	DO23846	LUAD	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.3056
p.S4321Y	DO23846	LUAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.2778
p.S4321Y	DO23846	LUAD	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.A4750D	DO45340	LUAD	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.0833
p.S4729Y	DO45322	LUAD	ICGC	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation rewiring degron network	0.1111
p.S4729Y	DO45322	LUAD	ICGC	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.2778
p.S4729Y	DO45322	LUAD	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.1111
p.P1493T	DO45317	LUAD	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1944
p.T4896M	DO24616	LUAD	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation altering degron motif	0.7423
p.S1990F	DO23643	LUAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1944
p.P3515T	DO23624	LUAD	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.0556
p.R3120K	DO23597	LUAD	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2778
p.T4657N	DO23592	LUAD	ICGC	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.1389
p.T4657N	DO23592	LUAD	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.T4657N	DO23592	LUAD	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.0556
p.W4849R	DO23570	LUAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.2222
p.T4848N	DO23570	LUAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.25
p.P3715A	DO23586	LUAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7503
p.P2652H	DO23580	LUAD	ICGC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0833
p.P3715Q	DO23562	LUAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7035
p.R3120M	DO26092	LUAD	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2778
p.R3120W	DO26092	LUAD	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2778
p.G4603D	DO26260	LUAD	ICGC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.1667
p.G4603D	DO41871	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.1667
p.L4334H	DO51189	LUAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.1667
p.G1492V	DO230530	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1667
p.T2057S	DO230961	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.2778
p.T2057S	DO224594	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.2778
p.P2055A	DO224563	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation altering degron motif	0.7503
p.R4907C	DO231075	LUSC	ICGC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.P2833Q	DO231096	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.2222
p.S4672C	DO231179	LUSC	ICGC	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.2778
p.S4672C	DO231179	LUSC	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.3056
p.P5292L	DO231176	LUSC	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.0833
p.T4617K	DO231186	LUSC	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.1111
p.P2574A	DO26999	LUSC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7503
p.T2027N	DO26822	LUSC	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.0833
p.T2027N	DO26822	LUSC	ICGC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation rewiring degron network	0.1667
p.T2274N	DO26544	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.2778
p.A3500G	DO26550	LUSC	ICGC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.754
p.T1666R	DO27747	LUSC	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.1111
p.T2279S	DO27747	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1389
p.T2279S	SIDM00458	Acute Myeloid Leukemia	GDSC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1389
p.T2279S	ACH-000751	Leukemia	CCLE	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1389
p.T2279S	OCI-M1	haematopoietic and lymphoid tissue	COSMIC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1389
p.P4646L	DO26494	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1944
p.T4379S	DO50102	LUSC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.6005
p.T4379S	DO42240	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.6005
p.G3851S	DO26464	LUSC	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.6993
p.G3851S	DO41903	UCEC	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.6993
p.G3851S	DO41871	UCEC	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.6993
p.P2271Q	DO26468	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation altering degron motif	0.7035
p.P3913S	DO26444	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1944
p.T1911A	DO26752	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation blocking phosphorylation signal	0.5833
p.T2983M	DO26647	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7423
p.T2983M	DO41380	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7423
p.T3926S	DO26659	LUSC	ICGC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.1944
p.T3926S	DO26659	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.2222
p.T3926S	DO26659	LUSC	ICGC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.1111
p.S2431C	DO45432	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.7541
p.S1973G	DO45549	LUSC	ICGC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1389
p.P3024S	DO45537	LUSC	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.6752
p.P4312A	DO223718	LUSC	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.7503
p.S3130T	DO223721	LUSC	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2778
p.T1678K	DO223723	LUSC	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.7306
p.T3273S	DO27620	LUSC	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.3056
p.T3273S	DO27620	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1667
p.T2573S	DO27620	LUSC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.3056
p.T2573S	DO27620	LUSC	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.1667
p.P2042R	DO27660	LUSC	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7512
p.S4636C	DO219185	LUSC	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.1389
p.S2988C	DO219182	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7541
p.V4368L	DO219177	LUSC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.V4368L	DO219177	LUSC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1389
p.T2977N	DO27596	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1667
p.P3103T	DO27208	LUSC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.7031
p.T2265S	DO27192	LUSC	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.25
p.S4358C	DO27025	LUSC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.7541
p.K3698E	DO52024	LUSC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1111
p.T5284P	DO228469	MALY	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.3056
p.T5284P	DO228469	MALY	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1944
p.T5284P	DO229229	THCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.3056
p.T5284P	DO229229	THCA	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1944
p.T5284P	DO229232	THCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.3056
p.T5284P	DO229232	THCA	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1944
p.V3056A	DO52652	MALY	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation altering degron motif	0.6936
p.P4083L	DO220851	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.7582
p.R4077K	DO220857	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.E1762K	DO220860	MELA	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7022
p.T3850I	DO220877	MELA	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.7078
p.S1499L	DO220884	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation altering degron motif	0.7667
p.A3713T	DO220891	MELA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7139
p.G4603S	DO220896	MELA	ICGC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.1667
p.P3528S	DO222415	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.6752
p.G1670S	DO222438	MELA	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.2222
p.G1670S	DO37423	SKCM	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.2222
p.G2277S	DO222532	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1944
p.G4086E	DO222632	MELA	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.7199
p.G4086E	DO50290	SKCM	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.7199
p.A3121V	DO222635	MELA	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.3056
p.S4842F	DO222908	MELA	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.7982
p.W2437C	DO231997	ORCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2222
p.A5276S	DO232061	ORCA	ICGC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation altering degron motif	0.7588
p.A5276S	DO232061	ORCA	ICGC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation altering degron motif	0.7588
p.P3303Q	DO46376	OV	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.2222
p.P3303Q	DO46376	OV	ICGC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.1944
p.S4316G	DO30310	OV	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.5833
p.S4316G	DO30310	OV	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.7222
p.T2701M	DO29248	OV	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.1944
p.T2065I	DO28471	OV	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.0556
p.A4652T	DO218974	PAAD	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation altering degron motif	0.7139
p.P1439L	DO32772	PAAD	ICGC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.1111
p.P3890T	DO49113	PACA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0556
p.P3890T	DO228762	PRAD	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.0556
p.P4360L	DO224705	PACA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.7582
p.R3888H	DO227933	PBCA	ICGC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1111
p.T4359I	DO35553	PBCA	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.5966
p.T4405A	DO232761	PBCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.2778
p.T4405A	DO232761	PBCA	ICGC	AATTT	DEG_SPOP_SBC_1	4398:4402	Mutation rewiring degron network	0.25
p.A3998V	DO232224	PBCA	ICGC	AATSS	DEG_SPOP_SBC_1	3984:3988	Mutation rewiring degron network	0.0556
p.T2282I	DO46792	PRAD	ICGC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation blocking phosphorylation signal	0.5
p.T4624R	DO51953	PRAD	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.3056
p.P4646Q	DO36299	PRAD	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.1944
p.A4553T	DO51407	PRAD	ICGC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.1667
p.V4596M	DO219446	PRAD	ICGC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation altering degron motif	0.7208
p.P3356Q	DO36598	READ	ICGC	VLTTT	DEG_SPOP_SBC_1	3361:3365	Mutation rewiring degron network	0.1944
p.T3704S	DO36447	READ	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1111
p.E4080K	DO36881	READ	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.2778
p.E4080K	DO43306	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.2778
p.S4557F	DO47048	RECA	ICGC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.2778
p.L2583V	DO46973	RECA	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation altering degron motif	0.6765
p.P3023L	DO219946	SARC	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.3056
p.P1636L	DO220073	SARC	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.0556
p.P1636L	DO220073	SARC	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1111
p.G3133R	DO220073	SARC	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.1944
p.G3133R	DO220073	SARC	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.1111
p.P4235L	DO220237	SARC	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7582
p.P4235L	DO220237	SARC	ICGC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7582
p.N3965T	DO219879	SKCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3963:3970	Mutation altering degron motif	0.7055
p.P1689L	DO229459	SKCA	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.7582
p.T3918P	DO229453	SKCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation altering degron motif	0.7031
p.G3162E	DO229453	SKCA	ICGC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.1944
p.T4828P	DO229453	SKCA	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.0556
p.T3351P	DO229470	SKCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3361:3365	Mutation rewiring degron network	0.0556
p.M4778L	DO218856	SKCA	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.1111
p.P3869L	DO218859	SKCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation altering degron motif	0.7582
p.R4733M	DO37523	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	4723:4727	Mutation rewiring degron network	0.1667
p.R4733M	DO37523	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.2222
p.I1909M	DO37896	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation substituting flanking lysine	0.3056
p.A3703T	DO37896	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.0833
p.A3703T	DO37951	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.0833
p.S4321F	DO37831	SKCM	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.2778
p.S4321F	DO37831	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.T3706I	DO47295	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1667
p.P4347L	DO47282	SKCM	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6111
p.P4347L	DO51282	SKCM	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6111
p.G3710E	DO37802	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.I3137F	DO37734	SKCM	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.0833
p.I3137F	DO37734	SKCM	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.2222
p.A1701T	DO37429	SKCM	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.0833
p.P4389S	DO37424	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.6752
p.H4782N	DO37423	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.G3529R	DO37406	SKCM	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7568
p.G2034E	DO37404	SKCM	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2778
p.R4306K	DO37471	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1667
p.R4306K	DO37471	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.2222
p.R4306K	DO47320	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1667
p.R4306K	DO47320	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.2222
p.R4306K	DO51298	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1667
p.R4306K	DO51298	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.2222
p.S4386Y	DO37445	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.712
p.A3849V	DO37444	SKCM	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation blocking phosphorylation signal	0.75
p.A3849V	DO37444	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation blocking phosphorylation signal	0.5278
p.A4318T	DO50299	SKCM	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.A4318T	DO50299	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.A3844V	DO50291	SKCM	ICGC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.1667
p.A3844V	DO50291	SKCM	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.0833
p.A3844V	DO50291	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.2222
p.L1656R	DO50288	SKCM	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.25
p.L1656R	DO50288	SKCM	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1111
p.R3049M	DO48702	SKCM	ICGC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1667
p.R3049M	DO48702	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.2222
p.E1658K	DO47329	SKCM	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.1944
p.E1658K	DO47329	SKCM	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.0556
p.P3103Q	DO47303	SKCM	ICGC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.7035
p.P3528Q	DO37966	SKCM	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7035
p.P4356S	DO47368	SKCM	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6752
p.P3132L	DO38111	SKCM	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2222
p.P3132L	DO38111	SKCM	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.0833
p.P3132L	DO51783	STAD	ICGC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation rewiring degron network	0.2222
p.P3132L	DO51783	STAD	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation rewiring degron network	0.0833
p.T1505I	DO38039	SKCM	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.25
p.P3055S	DO51301	SKCM	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation altering degron motif	0.6752
p.V1691M	DO51276	SKCM	ICGC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.7208
p.E4220K	DO51276	SKCM	ICGC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.0833
p.G3914R	DO51271	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.2222
p.G4248E	DO51273	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.3056
p.E1755K	DO51268	SKCM	ICGC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.25
p.S3440F	DO51259	SKCM	ICGC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.0833
p.S4672F	DO51298	SKCM	ICGC	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.2778
p.S4672F	DO51298	SKCM	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.3056
p.G4647E	DO38159	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2222
p.S3911F	DO38123	SKCM	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1389
p.G2991V	DO38123	SKCM	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.3056
p.G2991V	DO38123	SKCM	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1111
p.T4832I	DO219476	SKCM	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.1667
p.T4382P	DO38527	STAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7031
p.S4302F	DO38727	STAD	ICGC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.0556
p.S4302F	DO38727	STAD	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2778
p.S4302F	DO38727	STAD	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1111
p.P4328A	DO38727	STAD	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7503
p.A4294V	DO38727	STAD	ICGC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.2778
p.A4294V	DO38727	STAD	ICGC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2778
p.T2622N	DO51770	STAD	ICGC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.0556
p.G2034V	DO48009	STAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2778
p.W2994R	DO47757	STAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.W2994R	DO47757	STAD	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1944
p.P4347H	DO47903	STAD	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6111
p.A2049V	DO47989	STAD	ICGC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation blocking phosphorylation signal	0.5833
p.A2049V	DO47989	STAD	ICGC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation blocking phosphorylation signal	0.7222
p.P1913T	DO38336	STAD	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation blocking phosphorylation signal	0.5278
p.P4854L	DO38308	STAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.0833
p.P4854L	DO38214	STAD	ICGC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.0833
p.S2431A	DO229259	THCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.7588
p.T3293N	DO229253	THCA	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.7055
p.A4606V	DO229257	THCA	ICGC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.0833
p.S3382C	DO229268	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	3374:3380	Mutation rewiring degron network	0.2778
p.S3382C	DO229268	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.3056
p.A3362P	DO229272	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3361:3365	Mutation altering degron motif	0.7503
p.S3434N	DO229272	THCA	ICGC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.25
p.T2426M	DO229216	THCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.7423
p.T4657A	DO229216	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.1389
p.T4657A	DO229216	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.T4657A	DO229216	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.0556
p.P3715L	DO229218	THCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7582
p.P3715L	DO229224	THCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7582
p.P3715L	DO42865	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation altering degron motif	0.7582
p.A3321V	DO229218	THCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation blocking phosphorylation signal	0.5278
p.A3321V	DO229229	THCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation blocking phosphorylation signal	0.5278
p.A3321V	DO229240	THCA	ICGC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation blocking phosphorylation signal	0.5278
p.S3711P	DO229213	THCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.3056
p.I3975F	DO229227	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3975:3979	Mutation altering degron motif	0.7415
p.P4628H	DO229227	THCA	ICGC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation altering degron motif	0.7694
p.I2718F	DO229227	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	2718:2722	Mutation altering degron motif	0.7415
p.P4681Q	DO229227	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.0556
p.T2114N	DO229229	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.25
p.T2114N	DO229229	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.1667
p.A2678S	DO229221	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	2674:2680	Mutation altering degron motif	0.7588
p.A2678S	DO229221	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	2677:2681	Mutation altering degron motif	0.7588
p.A3930S	DO229245	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.3056
p.A3930S	DO229245	THCA	ICGC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.1111
p.A3930S	DO229245	THCA	ICGC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.2222
p.G3538A	DO234063	THCA	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.0833
p.V1983I	DO39363	THCA	ICGC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation altering degron motif	0.7076
p.T4371K	DO39018	THCA	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.R1934I	DO219771	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.2222
p.A4236T	DO219773	UCEC	ICGC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7139
p.T3286M	DO48174	UCEC	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1389
p.T3286M	DO48174	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.1111
p.T3286M	DO48174	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.25
p.V4348A	DO40801	UCEC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1944
p.T4558A	DO50076	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.3056
p.A3431T	DO40900	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.7139
p.P1647L	DO42177	UCEC	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.7582
p.P1647L	DO42177	UCEC	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation altering degron motif	0.7582
p.H2416N	DO42177	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.0556
p.T3680A	DO42129	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680A	SIDM00845	Burkitt's Lymphoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680A	SIDM00846	Cervical Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680A	SIDM00760	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.T3680A	SIDM01525	Acute Myeloid Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.25
p.V3208F	DO43306	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.0833
p.T2579I	DO43306	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation altering degron motif	0.7078
p.L1656P	DO42033	UCEC	ICGC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.25
p.L1656P	DO42033	UCEC	ICGC	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1111
p.S4352C	DO42023	UCEC	ICGC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.3056
p.P1978S	DO43602	UCEC	ICGC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.2778
p.T3005A	DO43602	UCEC	ICGC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.2778
p.T3005A	SIDM02074	Esophageal Carcinoma	GDSC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.2778
p.T1977K	DO43602	UCEC	ICGC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.25
p.L3028P	DO42384	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7582
p.T4648A	DO41020	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.25
p.A4745S	DO42280	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation blocking phosphorylation signal	0.6667
p.P1900S	DO43290	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.6752
p.T2139M	DO43186	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.0556
p.R1878C	DO43186	UCEC	ICGC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.2778
p.A4805T	DO43186	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0833
p.T1495M	DO43130	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.25
p.P4410T	DO43106	UCEC	ICGC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7031
p.T2723S	DO52412	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2706:2713	Mutation rewiring degron network	0.0556
p.T2723S	DO52412	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	2718:2722	Mutation rewiring degron network	0.3056
p.T2723S	DO52412	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation rewiring degron network	0.2222
p.H2578P	DO41752	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation altering degron motif	0.7694
p.G3529V	DO52402	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation altering degron motif	0.7532
p.G4579S	DO52402	UCEC	ICGC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.6993
p.S4380R	DO41758	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.2778
p.S4380R	DO41758	UCEC	ICGC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.3056
p.S3990T	DO42985	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	3984:3988	Mutation rewiring degron network	0.2778
p.T2830A	DO41644	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.3056
p.T2144M	DO41638	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.1944
p.T4257I	DO41584	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.0556
p.R1664I	DO41572	UCEC	ICGC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.0556
p.T3958M	DO41542	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3963:3970	Mutation rewiring degron network	0.1944
p.E2823K	DO41542	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.2778
p.P4085S	DO41999	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation altering degron motif	0.6752
p.T4806I	DO41871	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.0556
p.V2611L	DO41871	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation altering degron motif	0.6765
p.P2160H	DO41847	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.2222
p.P2160H	DO41847	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.3056
p.H3835R	DO43907	UCEC	ICGC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation altering degron motif	0.8244
p.P1904L	DO42576	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7582
p.S4677N	DO41241	UCEC	ICGC	MATPSSS	DEG_SCF_FBW7_1	4664:4670	Mutation rewiring degron network	0.1389
p.S4677N	DO41241	UCEC	ICGC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation rewiring degron network	0.1667
p.A4750V	DO42568	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	4737:4741	Mutation rewiring degron network	0.0833
p.T3530M	DO41235	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.3056
p.S3729I	DO41235	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.0556
p.S2472N	DO41235	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.0556
p.P2570S	DO41235	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.2222
p.P2570S	DO41235	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	2579:2583	Mutation rewiring degron network	0.0833
p.S2819N	DO41235	UCEC	ICGC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A3203T	DO43763	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.2222
p.T4315A	DO41109	UCEC	ICGC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.1111
p.T4315A	DO41109	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.3056
p.D1884N	DO43755	UCEC	ICGC	DDYSHCP	CBL_PTK	1880:1886	Mutation altering degron motif	0.6932
p.G951S	DO43755	UCEC	ICGC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.2222
p.A4800V	DO41199	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	4792:4796	Mutation rewiring degron network	0.2222
p.A2568T	DO42472	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	2574:2578	Mutation rewiring degron network	0.1667
p.T1897M	DO42825	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7423
p.S3266P	DO42713	UCEC	ICGC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.1111
p.A3431S	DO41361	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.7588
p.A3145V	DO42673	UCEC	ICGC	AATTT	DEG_SPOP_SBC_1	3141:3145	Mutation altering degron motif	0.6936
p.A3983T	DO42673	UCEC	ICGC	VLTTT	DEG_SPOP_SBC_1	3975:3979	Mutation rewiring degron network	0.2222
p.A3983T	DO42673	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	3984:3988	Mutation rewiring degron network	0.3056
p.N3408D	DO41331	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.6932
p.T2728A	DO41331	UCEC	ICGC	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7139
p.T3399M	DO41337	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.1389
p.P3299S	DO42665	UCEC	ICGC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.6752
p.T4771A	DO43971	UCEC	ICGC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.T3052P	DO43971	UCEC	ICGC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.0833
p.T3052P	DO43971	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.T3202M	DO43979	UCEC	ICGC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.25
p.T2423M	SIDM02039	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.25
p.P2039H	SIDM01307	Colorectal Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7694
p.P4325T	SIDM02015	Colorectal Carcinoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation altering degron motif	0.7031
p.T1748K	SIDM02010	Esophageal Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.0556
p.A3089T	SIDM00334	Endometrial Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.A3089T	SIDM00661	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.A3089T	ACH-000879	Endometrial/Uterine Cancer	CCLE	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.A3089T	ACH-000914	Lymphoma	CCLE	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.A3089T	MFE-296	endometrium	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.A3089T	HT	haematopoietic and lymphoid tissue	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1389
p.S3436Y	SIDM01156	Small Cell Lung Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.1944
p.S3436Y	ACH-000890	Lung Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.1944
p.S3436Y	SW1271	lung	COSMIC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.1944
p.S3123F	SIDM00135	Breast Carcinoma	GDSC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.6871
p.A3048T	SIDM01265	Plasma Cell Myeloma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM01265	Plasma Cell Myeloma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00773	Non-Cancerous	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00773	Non-Cancerous	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM01116	Non-Small Cell Lung Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00969	Ovarian Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00969	Ovarian Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00393	Gastric Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00393	Gastric Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00694	Other Solid Cancers	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00694	Other Solid Cancers	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00774	Breast Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM00774	Breast Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.A3048T	SIDM01664	Prostate Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1944
p.A3048T	SIDM01664	Prostate Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.1944
p.E4252K	SIDM00216	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.E4252K	SIDM00256	Neuroblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.E4252K	SIDM01577	Plasma Cell Myeloma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.E4252K	ACH-000989	Colon/Colorectal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.E4252K	SNU-175	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1944
p.S3524F	SIDM01096	Colorectal Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation blocking phosphorylation signal	0.75
p.S3524F	ACH-000400	Colon/Colorectal Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation blocking phosphorylation signal	0.75
p.S3524F	SK-CO-1	large intestine	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation blocking phosphorylation signal	0.75
p.A3841T	SIDM00922	Non-Small Cell Lung Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.0833
p.A3841T	SIDM00922	Non-Small Cell Lung Carcinoma	GDSC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1667
p.A3841T	SIDM00922	Non-Small Cell Lung Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.3056
p.T3533S	SIDM00194	Colorectal Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SIDM00234	Other Solid Cancers	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SIDM00533	Pancreatic Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SIDM00173	Head and Neck Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SIDM01588	Endometrial Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	ACH-000118	Pancreatic Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	ACH-000532	Colon/Colorectal Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	ACH-000563	Lung Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	ACH-000618	Head and Neck Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	ACH-002201	Cervical Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	EBC-1	lung	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	TC-YIK	cervix	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	SNU-61	large intestine	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.T3533S	HuP-T3	pancreas	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.2222
p.P3296L	SIDM00422	Hodgkin's Lymphoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.7582
p.P3296L	ACH-001203	Lymphoma	CCLE	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.7582
p.P3296L	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation altering degron motif	0.7582
p.L3051F	SIDM01104	Melanoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1111
p.L3051F	SIDM01104	Melanoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.2778
p.L3051F	ACH-000640	Skin Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1111
p.L3051F	ACH-000640	Skin Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.2778
p.L3051F	SK-MEL-31	skin	COSMIC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1111
p.L3051F	SK-MEL-31	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.2778
p.T4694I	SIDM00216	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.2778
p.T4694I	SIDM00216	Colorectal Carcinoma	GDSC	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation rewiring degron network	0.0556
p.T4694I	ACH-000989	Colon/Colorectal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.2778
p.T4694I	ACH-000989	Colon/Colorectal Cancer	CCLE	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation rewiring degron network	0.0556
p.E963K	SIDM00955	Melanoma	GDSC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.25
p.E963K	ACH-000812	Skin Cancer	CCLE	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.25
p.E963K	COLO-783	skin	COSMIC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.25
p.A2835G	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00620	Glioblastoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00319	Melanoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00454	Rhabdomyosarcoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM01117	Small Cell Lung Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM01126	Small Cell Lung Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00087	Plasma Cell Myeloma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00690	Head and Neck Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00917	Acute Myeloid Leukemia	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00878	Breast Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00254	Neuroblastoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM00808	Burkitt's Lymphoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM01617	Endometrial Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.A2835G	SIDM01254	Burkitt's Lymphoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.1667
p.T4246M	SIDM00672	Hepatocellular Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.6312
p.T4246M	SIDM01210	Glioblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.6312
p.T4246M	KNS-81-FD	central nervous system	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.6312
p.T4246M	Hep_3B2_1-7	NS	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.6312
p.L1666I	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.1111
p.L1666I	ACH-000995	Leukemia	CCLE	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.1111
p.L1666I	Jurkat	haematopoietic and lymphoid tissue	COSMIC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.1111
p.T4455S	SIDM00423	B-Cell Non-Hodgkin's Lymphoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.A2166T	SIDM01016	T-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.0556
p.A2166T	SIDM01016	T-Lymphoblastic Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.3056
p.A2166T	SIDM01263	T-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.0556
p.A2166T	SIDM01263	T-Lymphoblastic Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.3056
p.A2166T	ACH-000910	Breast Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.0556
p.A2166T	ACH-000910	Breast Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	2161:2165	Mutation rewiring degron network	0.3056
p.S3207C	SIDM00697	Small Cell Lung Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation blocking phosphorylation signal	0.5556
p.S3207C	ACH-000830	Lung Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation blocking phosphorylation signal	0.5556
p.S3207C	NCI-H1436	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation blocking phosphorylation signal	0.5556
p.G2044E	SIDM00545	Melanoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2778
p.G2044E	SIDM00545	Melanoma	GDSC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1389
p.G2044E	ACH-000987	Skin Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2778
p.G2044E	ACH-000987	Skin Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1389
p.G2044E	Mewo	skin	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.2778
p.G2044E	Mewo	skin	COSMIC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1389
p.P4615L	SIDM00857	Melanoma	GDSC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.0556
p.P4615L	SIDM01762	Esophageal Squamous Cell Carcinoma	GDSC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.0556
p.P4615L	T47D	breast	COSMIC	PTTTT	DEG_SPOP_SBC_1	4625:4629	Mutation rewiring degron network	0.0556
p.A4370T	SIDM00072	Non-Cancerous	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0556
p.A4370T	SIDM00072	Non-Cancerous	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1944
p.A4370T	SIDM00013	Melanoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0556
p.A4370T	SIDM00013	Melanoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1944
p.A4370T	SIDM00049	Colorectal Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0556
p.A4370T	SIDM00049	Colorectal Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.1944
p.T4690N	SIDM00957	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1667
p.T4371A	SIDM00330	Neuroblastoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.T4371A	SIDM00981	B-Cell Non-Hodgkin's Lymphoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.T4371A	SIDM00879	Breast Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.T4371A	SIDM00655	Other Solid Cancers	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.T4371A	SIDM01187	Breast Carcinoma	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.2222
p.N1871S	SIDM00684	Glioblastoma	GDSC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0833
p.N1871S	ACH-000595	Brain Cancer	CCLE	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0833
p.N1871S	LN-229	central nervous system	COSMIC	DDYSHCP	CBL_PTK	1880:1886	Mutation rewiring degron network	0.0833
p.T3870N	SIDM00845	Burkitt's Lymphoma	GDSC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.T3870N	SIDM00845	Burkitt's Lymphoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.3056
p.T3870N	SIDM00846	Cervical Carcinoma	GDSC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.T3870N	SIDM00846	Cervical Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.3056
p.T3870N	SIDM00760	Small Cell Lung Carcinoma	GDSC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.T3870N	SIDM00760	Small Cell Lung Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.3056
p.T3870N	SIDM01525	Acute Myeloid Leukemia	GDSC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.T3870N	SIDM01525	Acute Myeloid Leukemia	GDSC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.3056
p.T4688A	SIDM00845	Burkitt's Lymphoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM00846	Cervical Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM00257	Neuroblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM00720	Mesothelioma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM00760	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM01387	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4688A	SIDM01525	Acute Myeloid Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4696:4703	Mutation rewiring degron network	0.1111
p.T4671I	SIDM00967	Ovarian Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation altering degron motif	0.7078
p.T4671I	SIDM00841	Colorectal Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	4667:4671	Mutation altering degron motif	0.7078
p.R3534T	SIDM00831	Head and Neck Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.1944
p.T2038I	SIDM00495	B-Cell Non-Hodgkin's Lymphoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00584	Osteosarcoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00602	Gastric Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00492	Glioblastoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00564	Ovarian Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00488	Colorectal Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00502	B-Lymphoblastic Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00397	Acute Myeloid Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00289	B-Lymphoblastic Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00996	Thyroid Gland Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00591	Oral Cavity Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00273	Glioblastoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00575	Glioma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00531	Pancreatic Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM01727	Chronic Myelogenous Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM00168	Head and Neck Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM01685	B-Lymphoblastic Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM01662	Plasma Cell Myeloma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	SIDM01694	B-Lymphoblastic Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	NMC-G1	central nervous system	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	AM-38	central nervous system	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	8505C	thyroid	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	HAL-01	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	OVISE	ovary	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	A4-Fuk	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	GI-1	central nervous system	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	HuP-T4	pancreas	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	Set2	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	IM-95	stomach	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	CaR-1	large intestine	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	HO-1-u-1	upper aerodigestive tract	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.T2038I	HuO-3N1	bone	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.8189
p.G3191D	SIDM00781	Colorectal Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.2222
p.G3191D	SIDM00780	Colorectal Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.2222
p.G3191D	ACH-000967	Colon/Colorectal Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation rewiring degron network	0.2222
p.Q3939E	SIDM00680	Colorectal Carcinoma	GDSC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.2778
p.Q3939E	SIDM00680	Colorectal Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.3056
p.Q3939E	ACH-000957	Colon/Colorectal Cancer	CCLE	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.2778
p.Q3939E	ACH-000957	Colon/Colorectal Cancer	CCLE	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.3056
p.Q3939E	LS-180	large intestine	COSMIC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.2778
p.Q3939E	LS-180	large intestine	COSMIC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.3056
p.R4219C	SIDM00602	Gastric Carcinoma	GDSC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.0556
p.A2278S	SIDM01199	Hepatocellular Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.A2278S	ACH-000493	Liver Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.A2278S	SNU-423	liver	COSMIC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.A1453T	SIDM00855	Other Sarcomas	GDSC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation altering degron motif	0.6028
p.A1453T	SIDM00760	Small Cell Lung Carcinoma	GDSC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation altering degron motif	0.6028
p.S1950G	SIDM00855	Other Sarcomas	GDSC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1111
p.R4303M	SIDM00120	Prostate Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303M	SIDM00120	Prostate Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.R4303M	ACH-000979	Prostate Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303M	ACH-000979	Prostate Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.R4303M	DU-145	prostate	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.25
p.R4303M	DU-145	prostate	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1389
p.T4599M	SIDM00656	Burkitt's Lymphoma	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4599M	SIDM00309	Mesothelioma	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4599M	SIDM00431	T-Lymphoblastic Leukemia	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4599M	SIDM01681	Non-Cancerous	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4599M	SIDM00956	Esophageal Squamous Cell Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4599M	SIDM00641	Burkitt's Lymphoma	GDSC	VPTTT	DEG_SPOP_SBC_1	4593:4597	Mutation rewiring degron network	0.2778
p.T4237K	SIDM00652	Small Cell Lung Carcinoma	GDSC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237K	SIDM00652	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237K	SIDM00652	Small Cell Lung Carcinoma	GDSC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.T4237K	ACH-000780	Lung Cancer	CCLE	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237K	ACH-000780	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237K	ACH-000780	Lung Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.T4237K	NCI-H1105	lung	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237K	NCI-H1105	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237K	NCI-H1105	lung	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.A1678V	SIDM00643	Non-Cancerous	GDSC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.5825
p.A1678V	ACH-000327	Lung Cancer	CCLE	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.5825
p.A1678V	ACH-002363	Non-Cancerous	CCLE	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation altering degron motif	0.5825
p.S3908T	SIDM00643	Non-Cancerous	GDSC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.0556
p.S3908T	ACH-000327	Lung Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.0556
p.S3908T	ACH-002363	Non-Cancerous	CCLE	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.0556
p.P3154L	SIDM00266	Ewing's Sarcoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7582
p.P3154L	SIDM00362	Burkitt's Lymphoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7582
p.P3154L	SIDM00690	Head and Neck Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7582
p.P3154L	SIDM00230	Small Cell Lung Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7582
p.S2065F	SIDM00007	Other Solid Cancers	GDSC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.0556
p.S2065F	ACH-001550	Skin Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.0556
p.S2065F	MCC13	skin	COSMIC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.0556
p.S2651F	SIDM00007	Other Solid Cancers	GDSC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0556
p.S2651F	ACH-001550	Skin Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0556
p.S2651F	MCC13	skin	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0556
p.S4322N	SIDM00607	Glioblastoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.3056
p.S4322N	SIDM00607	Glioblastoma	GDSC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1111
p.S4322N	KNS-42	central nervous system	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.3056
p.S4322N	KNS-42	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1111
p.M3931T	SIDM00810	Non-Small Cell Lung Carcinoma	GDSC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation altering degron motif	0.7423
p.M3931T	ACH-000757	Lung Cancer	CCLE	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation altering degron motif	0.7423
p.M3931T	A427	lung	COSMIC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation altering degron motif	0.7423
p.T2989M	SIDM00623	Other Blood Cancers	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.6312
p.T2989M	SIDM01761	Rhabdomyosarcoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.6312
p.L4450V	SIDM00463	T-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.25
p.L4450V	ACH-000372	Leukemia	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.25
p.L4450V	P12-ICHIKAWA	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.25
p.P4771L	SIDM00369	Esophageal Squamous Cell Carcinoma	GDSC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.P4771L	ACH-000647	Esophageal Cancer	CCLE	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.P4771L	TE-1	oesophagus	COSMIC	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.T4570S	SIDM00741	Small Cell Lung Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.1111
p.T4570S	SIDM00741	Small Cell Lung Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.1389
p.T4570S	ACH-000431	Lung Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.1111
p.T4570S	ACH-000431	Lung Cancer	CCLE	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.1389
p.T4570S	NCI-H1694	lung	COSMIC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.1111
p.T4570S	NCI-H1694	lung	COSMIC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation rewiring degron network	0.1389
p.T4234A	SIDM01259	B-Lymphoblastic Leukemia	GDSC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6028
p.T4234A	SIDM01259	B-Lymphoblastic Leukemia	GDSC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7139
p.T4234A	ACH-002238	Leukemia	CCLE	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6028
p.T4234A	ACH-002238	Leukemia	CCLE	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7139
p.T4234A	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.6028
p.T4234A	GR-ST	haematopoietic and lymphoid tissue	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7139
p.S1664N	SIDM00447	B-Lymphoblastic Leukemia	GDSC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.0556
p.S1664N	ACH-000960	Leukemia	CCLE	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.0556
p.S1664N	REH	haematopoietic and lymphoid tissue	COSMIC	PTTPAGS	DEG_SCF_FBW7_1	1674:1680	Mutation rewiring degron network	0.0556
p.P3414H	SIDM00447	B-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.3056
p.P3414H	SIDM00447	B-Lymphoblastic Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	3418:3422	Mutation rewiring degron network	0.2222
p.T3501N	SIDM00329	Hodgkin's Lymphoma	GDSC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.3056
p.S4834F	SIDM00583	Pancreatic Carcinoma	GDSC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.2222
p.S4834F	ACH-001107	Pancreatic Cancer	CCLE	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.2222
p.S4834F	KP-1N	pancreas	COSMIC	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation rewiring degron network	0.2222
p.T4275I	SIDM01028	Esophageal Squamous Cell Carcinoma	GDSC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.0556
p.T4275I	ACH-000809	Esophageal Cancer	CCLE	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.0556
p.T4275I	KYSE-410	oesophagus	COSMIC	PATTPTAT	DEG_SCF_FBW7_1	4285:4292	Mutation rewiring degron network	0.0556
p.L2690M	SIDM00660	Colorectal Carcinoma	GDSC	MATPSSS	DEG_SCF_FBW7_1	2674:2680	Mutation rewiring degron network	0.0556
p.L2690M	SIDM00660	Colorectal Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	2677:2681	Mutation rewiring degron network	0.0833
p.G2615S	SIDM00581	Glioblastoma	GDSC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.25
p.G2615S	ACH-000738	Brain Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.25
p.G2615S	GB-1	central nervous system	COSMIC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.25
p.A3428D	SIDM00190	Melanoma	GDSC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.6682
p.S4436C	SIDM00744	Non-Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.2222
p.S4436C	ACH-000893	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.2222
p.S4436C	NCI-H1651	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.2222
p.L1772F	SIDM00748	Non-Small Cell Lung Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.0556
p.L1772F	ACH-000015	Lung Cancer	CCLE	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.0556
p.L1772F	NCI-H1581	lung	COSMIC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation rewiring degron network	0.0556
p.L1693F	SIDM00293	Small Cell Lung Carcinoma	GDSC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.3056
p.L1693F	ACH-002052	Lung Cancer	CCLE	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.3056
p.L1693F	LU-139	lung	COSMIC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation rewiring degron network	0.3056
p.V4345M	SIDM00293	Small Cell Lung Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.V4345M	OSC-20	upper aerodigestive tract	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.V4345M	LU-139	lung	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.1111
p.L4253M	SIDM00320	Non-Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1667
p.L4253M	ACH-001233	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1667
p.L4253M	VMRC-LCD	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.1667
p.T4372S	SIDM00917	Acute Myeloid Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.0556
p.T4372S	SIDM00917	Acute Myeloid Leukemia	GDSC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.25
p.T4372S	CESS	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation rewiring degron network	0.0556
p.T4372S	CESS	haematopoietic and lymphoid tissue	COSMIC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation rewiring degron network	0.25
p.T3429N	SIDM00990	Non-Small Cell Lung Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation altering degron motif	0.7055
p.A4907S	SIDM01218	Other Solid Cancers	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.A4907S	ACH-001530	Endometrial/Uterine Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.A4907S	JEG-3	placenta	COSMIC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.T2282N	SIDM00761	Small Cell Lung Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation blocking phosphorylation signal	0.5
p.T2282N	ACH-000752	Lung Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation blocking phosphorylation signal	0.5
p.T2282N	NCI-H196	lung	COSMIC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation blocking phosphorylation signal	0.5
p.S3041C	SIDM00523	Small Cell Lung Carcinoma	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation altering degron motif	0.8652
p.S3041C	ACH-000698	Lung Cancer	CCLE	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation altering degron motif	0.8652
p.S3041C	DMS-53	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation altering degron motif	0.8652
p.A3710T	SIDM00238	Ovarian Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	SIDM00081	Melanoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	SIDM00247	Gastric Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	SIDM01471	Chronic Myelogenous Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	ACH-000356	Gastric Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	ACH-000947	Ovarian Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	MKN45	stomach	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	OVK-18	ovary	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.A3710T	SK-MEL-28	skin	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.2778
p.T3264I	SIDM00619	Thyroid Gland Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0556
p.T3264I	KMH-2	thyroid	COSMIC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0556
p.T2610N	SIDM01093	Cervical Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation altering degron motif	0.7055
p.T2610N	SiHa	cervix	COSMIC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation altering degron motif	0.7055
p.A4649P	SIDM01093	Cervical Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649P	SIDM00534	Colorectal Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649P	ACH-000556	Cervical Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649P	ACH-000986	Colon/Colorectal Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.A4649P	ACH-002847	Unknown	CCLE	VLTTT	DEG_SPOP_SBC_1	4651:4655	Mutation rewiring degron network	0.2778
p.S4236Y	SIDM00282	Colorectal Carcinoma	GDSC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.712
p.S4236Y	ACH-000998	Colon/Colorectal Cancer	CCLE	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.712
p.S4236Y	CW-2	large intestine	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.712
p.T3273I	SIDM00965	Small Cell Lung Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.3056
p.T3273I	SIDM00965	Small Cell Lung Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1667
p.T3273I	ACH-000800	Lung Cancer	CCLE	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.3056
p.T3273I	ACH-000800	Lung Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1667
p.T3273I	NCI-H446	lung	COSMIC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.3056
p.T3273I	NCI-H446	lung	COSMIC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1667
p.S4583T	SIDM00965	Small Cell Lung Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.7116
p.S4583T	ACH-000800	Lung Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.7116
p.S4583T	NCI-H446	lung	COSMIC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.7116
p.V1650I	SIDM00333	Endometrial Carcinoma	GDSC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.7076
p.V1650I	ACH-000988	Endometrial/Uterine Cancer	CCLE	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.7076
p.V1650I	MFE-319	endometrium	COSMIC	STTAVPTL	DEG_COP1_1	1646:1653	Mutation altering degron motif	0.7076
p.I3094V	SIDM00333	Endometrial Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.2778
p.I3094V	ACH-000988	Endometrial/Uterine Cancer	CCLE	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.2778
p.I3094V	MFE-319	endometrium	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.2778
p.T1991A	SIDM00136	Colorectal Carcinoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1667
p.T1991A	SIDM00793	Burkitt's Lymphoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.1667
p.S3198N	SIDM00151	Ovarian Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation altering degron motif	0.7069
p.S3198N	IGROV-1	ovary	COSMIC	VLTST	DEG_SPOP_SBC_1	3195:3199	Mutation altering degron motif	0.7069
p.P3406R	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7512
p.Y1882C	SIDM00683	Prostate Carcinoma	GDSC	DDYSHCP	CBL_PTK	1880:1886	Mutation altering degron motif	0.7087
p.Y1882C	LNCaP-Clone-FGC	prostate	COSMIC	DDYSHCP	CBL_PTK	1880:1886	Mutation altering degron motif	0.7087
p.T3943A	SIDM00683	Prostate Carcinoma	GDSC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.1667
p.T3943A	SIDM00683	Prostate Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.1944
p.S2979C	SIDM00767	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.S2979C	ACH-001136	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.S2979C	NCI-H187	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.T2994I	SIDM00767	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.T2994I	SIDM00767	Small Cell Lung Carcinoma	GDSC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1944
p.T2994I	ACH-001136	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.T2994I	ACH-001136	Lung Cancer	CCLE	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1944
p.T2994I	NCI-H187	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2222
p.T2994I	NCI-H187	lung	COSMIC	AATTT	DEG_SPOP_SBC_1	2999:3003	Mutation rewiring degron network	0.1944
p.A1977V	SIDM01045	Endometrial Carcinoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.25
p.A1977V	ACH-000978	Endometrial/Uterine Cancer	CCLE	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.25
p.A1977V	EN	endometrium	COSMIC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.25
p.T2423A	SIDM01045	Endometrial Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.25
p.T2423A	EN	endometrium	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.25
p.S3126A	SIDM01045	Endometrial Carcinoma	GDSC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.6477
p.S3126A	ACH-000978	Endometrial/Uterine Cancer	CCLE	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.6477
p.S3126A	EN	endometrium	COSMIC	MSTPSST	DEG_SCF_FBW7_1	3122:3128	Mutation altering degron motif	0.6477
p.A3846T	SIDM01045	Endometrial Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846T	SIDM01045	Endometrial Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.A3846T	SIDM01449	Pancreatic Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846T	SIDM01449	Pancreatic Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.A3846T	ACH-000961	Endometrial/Uterine Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846T	ACH-000961	Endometrial/Uterine Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.A3846T	ACH-000978	Endometrial/Uterine Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846T	ACH-000978	Endometrial/Uterine Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.A3846T	EN	endometrium	COSMIC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.2222
p.A3846T	EN	endometrium	COSMIC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.1667
p.A4092G	SIDM00871	Non-Cancerous	GDSC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1667
p.A4092G	SIDM00872	Breast Carcinoma	GDSC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1667
p.G3440V	SIDM00114	Non-Small Cell Lung Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.0833
p.G3440V	H513	pleura	COSMIC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.0833
p.A3423T	SIDM00272	Breast Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation rewiring degron network	0.0556
p.A3423T	SIDM00272	Breast Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3418:3422	Mutation rewiring degron network	0.3056
p.A3423T	SIDM00272	Breast Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	3427:3431	Mutation rewiring degron network	0.2222
p.T3823I	SIDM00948	Burkitt's Lymphoma	GDSC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1111
p.T3823I	ACH-002232	Lymphoma	CCLE	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1111
p.T3823I	DG-75	haematopoietic and lymphoid tissue	COSMIC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1111
p.T3111M	SIDM00488	Colorectal Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1111
p.T3111M	ACH-002345	Colon/Colorectal Cancer	CCLE	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1111
p.T3111M	CaR-1	large intestine	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation rewiring degron network	0.1111
p.T2432M	SIDM00003	Melanoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T2432M	SIDM00214	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T2432M	SIDM00640	Mesothelioma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T2432M	SNU-407	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T2432M	M14	skin	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T2432M	MSTO-211H	pleura	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation altering degron motif	0.6312
p.T4437M	SIDM00214	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.25
p.T4437M	SNU-407	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.25
p.T3489M	SIDM00121	T-Lymphoblastic Leukemia	GDSC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.1389
p.T3489M	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.1389
p.T4237M	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237M	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237M	SIDM00121	T-Lymphoblastic Leukemia	GDSC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.T4237M	ACH-001738	Leukemia	CCLE	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237M	ACH-001738	Leukemia	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237M	ACH-001738	Leukemia	CCLE	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.T4237M	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation rewiring degron network	0.2778
p.T4237M	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation rewiring degron network	0.25
p.T4237M	CCRF-CEM	haematopoietic and lymphoid tissue	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation rewiring degron network	0.3056
p.P3853H	SIDM01064	Hodgkin's Lymphoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.7694
p.T3697I	SIDM01127	Non-Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1389
p.T3697I	ACH-000628	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1389
p.T3697I	NCI-H596	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1389
p.A4432T	SIDM00247	Gastric Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.A4432T	ACH-000356	Gastric Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.A4432T	MKN45	stomach	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4440:4447	Mutation rewiring degron network	0.1111
p.T2124R	SIDM01680	Non-Cancerous	GDSC	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation altering degron motif	0.7876
p.S47Y	SIDM00730	Small Cell Lung Carcinoma	GDSC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.8231
p.S47Y	ACH-000610	Lung Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.8231
p.E3101D	SIDM00903	Non-Small Cell Lung Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.5647
p.E3101D	ACH-000681	Lung Cancer	CCLE	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.5647
p.E3101D	A549	lung	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.5647
p.E4077V	SIDM01102	Non-Cancerous	GDSC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.E4077V	ACH-002316	Non-Cancerous	CCLE	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.E4077V	WIL2-NS	haematopoietic and lymphoid tissue	COSMIC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.1944
p.P1910L	SIDM01210	Glioblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.1667
p.P1910L	ACH-002259	Brain Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.1667
p.P1910L	KNS-81-FD	central nervous system	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.1667
p.T3499A	SIDM00537	Colorectal Carcinoma	GDSC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.T3499A	ACH-000982	Colon/Colorectal Cancer	CCLE	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.T3499A	ACH-001345	Colon/Colorectal Cancer	CCLE	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.T3499A	GP5d	large intestine	COSMIC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation altering degron motif	0.7139
p.P1457A	SIDM00582	Pancreatic Carcinoma	GDSC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation altering degron motif	0.6392
p.P1457A	KP-2	pancreas	COSMIC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation altering degron motif	0.6392
p.T4312R	SIDM00988	Kidney Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.7876
p.T4312R	BFTC-909	kidney	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation altering degron motif	0.7876
p.A1689S	SIDM01721	Non-Cancerous	GDSC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.6477
p.A1689S	SIDM00191	Kidney Carcinoma	GDSC	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.6477
p.A1689S	ACH-002090	Kidney Cancer	CCLE	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.6477
p.A1689S	ACH-002344	Non-Cancerous	CCLE	VATST	DEG_SPOP_SBC_1	1688:1692	Mutation altering degron motif	0.6477
p.E3724K	SIDM01159	Other Sarcomas	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1944
p.E3724K	SW872	soft tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1944
p.R1994H	SIDM00793	Burkitt's Lymphoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.0833
p.A2424S	SIDM00793	Burkitt's Lymphoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2778
p.A2424S	SIDM01133	Other Solid Cancers	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2778
p.T4359S	SIDM00793	Burkitt's Lymphoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6005
p.T4359S	SIDM01133	Other Solid Cancers	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6005
p.T4359S	NCI-H835	lung	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6005
p.T4359S	EB-3	haematopoietic and lymphoid tissue	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation altering degron motif	0.6005
p.L1988P	SIDM01133	Other Solid Cancers	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.25
p.S4242C	SIDM00560	Gastric Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.643
p.S4242C	ACH-000678	Gastric Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.643
p.S4242C	MKN7	stomach	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4240:4247	Mutation altering degron motif	0.643
p.T1949I	SIDM00954	Breast Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1389
p.T1949I	COLO-824	breast	COSMIC	VLTTT	DEG_SPOP_SBC_1	1938:1942	Mutation rewiring degron network	0.1389
p.V3926E	SIDM00954	Breast Carcinoma	GDSC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.1944
p.V3926E	SIDM00954	Breast Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.2222
p.V3926E	SIDM00954	Breast Carcinoma	GDSC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.1111
p.V3926E	SIDM01686	Chronic Myelogenous Leukemia	GDSC	MATPSSS	DEG_SCF_FBW7_1	3931:3937	Mutation rewiring degron network	0.1944
p.V3926E	SIDM01686	Chronic Myelogenous Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	3918:3922	Mutation rewiring degron network	0.2222
p.V3926E	SIDM01686	Chronic Myelogenous Leukemia	GDSC	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.1111
p.M2425I	SIDM00217	Colorectal Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.3056
p.M2425I	ACH-000999	Colon/Colorectal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.3056
p.M2425I	SNU-1040	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.3056
p.A4574V	SIDM00217	Colorectal Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.2222
p.A4574V	ACH-000999	Colon/Colorectal Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.2222
p.A4574V	SNU-1040	large intestine	COSMIC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation rewiring degron network	0.2222
p.A3029T	SIDM00145	T-Lymphoblastic Leukemia	GDSC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.3056
p.A3029T	SIDM00145	T-Lymphoblastic Leukemia	GDSC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.0556
p.A3029T	ACH-001127	Leukemia	CCLE	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.3056
p.A3029T	ACH-001127	Leukemia	CCLE	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.0556
p.A3029T	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.3056
p.A3029T	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.0556
p.S4235R	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7427
p.S4235R	SIDM00145	T-Lymphoblastic Leukemia	GDSC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7427
p.S4235R	ACH-001127	Leukemia	CCLE	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7427
p.S4235R	ACH-001127	Leukemia	CCLE	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7427
p.S4235R	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PSTPATS	DEG_SCF_FBW7_1	4229:4235	Mutation altering degron motif	0.7427
p.S4235R	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	PATSS	DEG_SPOP_SBC_1	4232:4236	Mutation altering degron motif	0.7427
p.T4418I	SIDM00864	Cervical Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.2222
p.T4418I	DoTc2-4510	cervix	COSMIC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.2222
p.P3530L	SIDM01229	Neuroblastoma	GDSC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.3056
p.P3530L	BE2-M17	autonomic ganglia	COSMIC	PGTTT	DEG_SPOP_SBC_1	3525:3529	Mutation rewiring degron network	0.3056
p.I2435N	SIDM00658	Non-Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2778
p.I2435N	ACH-000852	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2778
p.I2435N	NCI-H1435	lung	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2778
p.P2043T	SIDM00951	T-Lymphoblastic Leukemia	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.3056
p.P2043T	SIDM00951	T-Lymphoblastic Leukemia	GDSC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1111
p.P2043T	ACH-002222	Leukemia	CCLE	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.3056
p.P2043T	ACH-002222	Leukemia	CCLE	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1111
p.P2043T	CTV-1	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.3056
p.P2043T	CTV-1	haematopoietic and lymphoid tissue	COSMIC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1111
p.P4087S	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.3056
p.P4087S	ACH-002222	Leukemia	CCLE	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.3056
p.P4087S	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.3056
p.P4344S	SIDM00951	T-Lymphoblastic Leukemia	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.P4344S	ACH-002222	Leukemia	CCLE	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.P4344S	CTV-1	haematopoietic and lymphoid tissue	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation rewiring degron network	0.0833
p.T1630M	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.1389
p.T1630M	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.1389
p.T1630M	SIDM01525	Acute Myeloid Leukemia	GDSC	ATTTT	DEG_SPOP_SBC_1	1619:1623	Mutation rewiring degron network	0.1389
p.S2815I	SIDM00622	Glioblastoma	GDSC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.0556
p.S2815I	ACH-002224	Brain Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.0556
p.S2815I	D-247MG	central nervous system	COSMIC	PGTTT	DEG_SPOP_SBC_1	2825:2829	Mutation rewiring degron network	0.0556
p.P3410Q	SIDM00770	Small Cell Lung Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7035
p.P3410Q	ACH-000559	Lung Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3406:3413	Mutation altering degron motif	0.7035
p.A4889D	SIDM00738	Non-Small Cell Lung Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1944
p.A4889D	ACH-000282	Lung Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1944
p.A4889D	NCI-H1755	lung	COSMIC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1944
p.P2983H	SIDM00233	T-Lymphoblastic Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7694
p.P2983H	ACH-002058	Leukemia	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7694
p.P2983H	ATN-1	haematopoietic and lymphoid tissue	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation altering degron motif	0.7694
p.A2594S	SIDM00261	Ewing's Sarcoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6477
p.A2594S	ACH-002109	Bone Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6477
p.A2594S	ES8	bone	COSMIC	VATPSST	DEG_SCF_FBW7_1	2593:2599	Mutation altering degron motif	0.6477
p.A3058T	SIDM00451	T-Lymphoblastic Leukemia	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.A3058T	SIDM00500	Colorectal Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.A3058T	ACH-000937	Leukemia	CCLE	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.A3058T	PF-382	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	3053:3057	Mutation rewiring degron network	0.3056
p.T3842I	SIDM00150	Colorectal Carcinoma	GDSC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.1111
p.T3842I	SIDM00150	Colorectal Carcinoma	GDSC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1389
p.T3842I	SIDM00150	Colorectal Carcinoma	GDSC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.2778
p.T3842I	ACH-000969	Colon/Colorectal Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.1111
p.T3842I	ACH-000969	Colon/Colorectal Cancer	CCLE	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1389
p.T3842I	ACH-000969	Colon/Colorectal Cancer	CCLE	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.2778
p.T3842I	KM12	large intestine	COSMIC	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation rewiring degron network	0.1111
p.T3842I	KM12	large intestine	COSMIC	AHTST	DEG_SPOP_SBC_1	3831:3835	Mutation rewiring degron network	0.1389
p.T3842I	KM12	large intestine	COSMIC	VLTTT	DEG_SPOP_SBC_1	3836:3840	Mutation rewiring degron network	0.2778
p.T3874I	SIDM00150	Colorectal Carcinoma	GDSC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.3056
p.T3874I	SIDM00150	Colorectal Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.T3874I	ACH-000969	Colon/Colorectal Cancer	CCLE	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.3056
p.T3874I	ACH-000969	Colon/Colorectal Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.T3874I	KM12	large intestine	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.3056
p.T3874I	KM12	large intestine	COSMIC	VPTTT	DEG_SPOP_SBC_1	3865:3869	Mutation rewiring degron network	0.1944
p.S3685L	SIDM00774	Breast Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.6556
p.S3685L	ACH-000691	Breast Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.6556
p.S3685L	HCC2157	breast	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation altering degron motif	0.6556
p.P4415T	SIDM01140	Ovarian Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation rewiring degron network	0.3056
p.T1762M	SIDM00257	Neuroblastoma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7423
p.T1762M	SIDM00720	Mesothelioma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7423
p.T1762M	SIDM01387	Small Cell Lung Carcinoma	GDSC	AETST	DEG_SPOP_SBC_1	1758:1762	Mutation altering degron motif	0.7423
p.T5266R	SIDM00720	Mesothelioma	GDSC	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.0556
p.T5266R	SIDM00720	Mesothelioma	GDSC	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.0833
p.T46M	SIDM01086	B-Lymphoblastic Leukemia	GDSC	APTSS	DEG_SPOP_SBC_1	44:48	Mutation altering degron motif	0.7423
p.I2140F	SIDM01173	Rhabdomyosarcoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2149:2156	Mutation rewiring degron network	0.0833
p.V4559I	SIDM01609	Endometrial Carcinoma	GDSC	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation altering degron motif	0.7076
p.V4559I	ACH-000972	Endometrial/Uterine Cancer	CCLE	VHTST	DEG_SPOP_SBC_1	4559:4563	Mutation altering degron motif	0.7076
p.A2419T	SIDM01608	Endometrial Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.1389
p.S4720N	SIDM01608	Endometrial Carcinoma	GDSC	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation altering degron motif	0.7069
p.S4720N	ACH-000990	Endometrial/Uterine Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	4717:4721	Mutation altering degron motif	0.7069
p.A4907V	SIDM01608	Endometrial Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.A4907V	ACH-000990	Endometrial/Uterine Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.0833
p.S2422F	SIDM01617	Endometrial Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2426:2433	Mutation rewiring degron network	0.2222
p.T3028P	SIDM01617	Endometrial Carcinoma	GDSC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation altering degron motif	0.7031
p.P2653Q	SIDM01686	Chronic Myelogenous Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.1111
p.T3314M	SIDM01664	Prostate Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.2778
p.W1905R	SIDM01635	Glioblastoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.W1905R	ACH-000027	Brain Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation rewiring degron network	0.3056
p.T2446A	SIDM01611	Endometrial Carcinoma	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2455:2462	Mutation rewiring degron network	0.0833
p.K1465T	SIDM01450	Gastric Carcinoma	GDSC	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation substituting flanking lysine	0.2222
p.K1465T	ACH-000898	Gastric Cancer	CCLE	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation substituting flanking lysine	0.2222
p.T4347A	SIDM01450	Gastric Carcinoma	GDSC	PSSTPETT	DEG_SCF_FBW7_1	4353:4360	Mutation blocking phosphorylation signal	0.6111
p.T3151K	SIDM01387	Small Cell Lung Carcinoma	GDSC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.6195
p.T2045R	SIDM01763	Rhabdomyosarcoma	GDSC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation rewiring degron network	0.25
p.T2045R	SIDM01763	Rhabdomyosarcoma	GDSC	VPTTT	DEG_SPOP_SBC_1	2051:2055	Mutation rewiring degron network	0.1667
p.R3288S	SIDM01442	Glioma	GDSC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1944
p.R3288S	SIDM01442	Glioma	GDSC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0556
p.R3288S	SIDM01442	Glioma	GDSC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1944
p.T3494A	SIDM01343	Gastric Carcinoma	GDSC	AATTS	DEG_SPOP_SBC_1	3496:3500	Mutation rewiring degron network	0.2778
p.G3315R	SIDM01729	Endometrial Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.25
p.G3315R	ACH-000697	Lymphoma	CCLE	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.25
p.G3315R	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	VPTTT	DEG_SPOP_SBC_1	3308:3312	Mutation rewiring degron network	0.25
p.T1981A	SIDM01619	Endometrial Carcinoma	GDSC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation altering degron motif	0.7139
p.F2616L	SIDM01525	Acute Myeloid Leukemia	GDSC	VLTTT	DEG_SPOP_SBC_1	2608:2612	Mutation rewiring degron network	0.2222
p.S2978N	SIDM01525	Acute Myeloid Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1944
p.S2978R	SIDM01525	Acute Myeloid Leukemia	GDSC	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.1944
p.T3033P	ACH-000024	Myeloma	CCLE	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1944
p.T3033P	ACH-000024	Myeloma	CCLE	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1667
p.T3033P	OPM-2	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	3024:3028	Mutation rewiring degron network	0.1944
p.T3033P	OPM-2	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	3039:3043	Mutation rewiring degron network	0.1667
p.S2731N	ACH-000028	Breast Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7069
p.S2731N	ACH-000667	Lung Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7069
p.S2731N	ACH-000759	Breast Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7069
p.S2731N	ACH-000908	Gastric Cancer	CCLE	AATSS	DEG_SPOP_SBC_1	2727:2731	Mutation altering degron motif	0.7069
p.S1986P	ACH-000105	Leukemia	CCLE	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.3056
p.S1986P	ALL-SIL	haematopoietic and lymphoid tissue	COSMIC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation rewiring degron network	0.3056
p.P3388Q	ACH-000198	Leukemia	CCLE	MATPSSS	DEG_SCF_FBW7_1	3374:3380	Mutation rewiring degron network	0.1111
p.P3388Q	ACH-000198	Leukemia	CCLE	PSSST	DEG_SPOP_SBC_1	3377:3381	Mutation rewiring degron network	0.1389
p.T3852N	ACH-000252	Colon/Colorectal Cancer	CCLE	VATPSST	DEG_SCF_FBW7_1	3850:3856	Mutation altering degron motif	0.8166
p.S3678R	ACH-000312	Neuroblastoma	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3683:3690	Mutation rewiring degron network	0.1944
p.A1448D	ACH-000431	Lung Cancer	CCLE	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation altering degron motif	0.6682
p.P2131L	ACH-000785	Lung Cancer	CCLE	MATPSSS	DEG_SCF_FBW7_1	2117:2123	Mutation rewiring degron network	0.1111
p.P2131L	ACH-000785	Lung Cancer	CCLE	PSSST	DEG_SPOP_SBC_1	2120:2124	Mutation rewiring degron network	0.1389
p.I4705L	ACH-000801	Skin Cancer	CCLE	PITPVLT	DEG_SCF_FBW7_1	4704:4710	Mutation altering degron motif	0.6063
p.S4329C	ACH-000839	Bladder Cancer	CCLE	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation rewiring degron network	0.3056
p.A2278G	ACH-000920	Leukemia	CCLE	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.A2278G	CCK-81	large intestine	COSMIC	PGTTT	DEG_SPOP_SBC_1	2268:2272	Mutation rewiring degron network	0.1667
p.T1900A	ACH-000940	Endometrial/Uterine Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7139
p.T1900A	AN3-CA	endometrium	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	1897:1904	Mutation altering degron motif	0.7139
p.A2981V	ACH-000954	Endometrial/Uterine Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	2983:2990	Mutation rewiring degron network	0.2778
p.S4711T	ACH-000961	Endometrial/Uterine Cancer	CCLE	VLTST	DEG_SPOP_SBC_1	4708:4712	Mutation altering degron motif	0.6005
p.D41G	ACH-000964	Leukemia	CCLE	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.25
p.M4886I	ACH-000975	Lung Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	4894:4898	Mutation rewiring degron network	0.1111
p.E3704A	ACH-000989	Colon/Colorectal Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1111
p.E3704A	SNU-175	large intestine	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	3712:3719	Mutation rewiring degron network	0.1111
p.G42S	ACH-000990	Endometrial/Uterine Cancer	CCLE	APTSS	DEG_SPOP_SBC_1	44:48	Mutation rewiring degron network	0.2778
p.S4839F	ACH-001028	Rhabdoid	CCLE	LSSTPGTT	DEG_SCF_FBW7_1	4838:4845	Mutation altering degron motif	0.6871
p.A5270T	ACH-001280	Sarcoma	CCLE	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation rewiring degron network	0.1667
p.A5270T	ACH-001280	Sarcoma	CCLE	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation rewiring degron network	0.1944
p.P4771S	ACH-001301	Neuroblastoma	CCLE	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.3056
p.Q1459H	ACH-001698	Head and Neck Cancer	CCLE	SASTEPAVPTP	DEG_COP1_1	1447:1457	Mutation rewiring degron network	0.2778
p.P5275L	ACH-001740	Sarcoma	CCLE	PVSST	DEG_SPOP_SBC_1	5275:5279	Mutation altering degron motif	0.7582
p.T5283P	ACH-001957	Bone Cancer	CCLE	VSSTPTPT	DEG_SCF_FBW7_1	5276:5283	Mutation altering degron motif	0.7031
p.P1637S	ACH-001997	Bile Duct Cancer	CCLE	STTAVPTL	DEG_COP1_1	1646:1653	Mutation rewiring degron network	0.0833
p.P1637S	ACH-001997	Bile Duct Cancer	CCLE	PASTT	DEG_SPOP_SBC_1	1644:1648	Mutation rewiring degron network	0.1389
p.I3948T	ACH-002061	Leukemia	CCLE	PSSST	DEG_SPOP_SBC_1	3934:3938	Mutation rewiring degron network	0.0556
p.S4756P	ACH-002122	Lung Cancer	CCLE	AQTTT	DEG_SPOP_SBC_1	4766:4770	Mutation rewiring degron network	0.0556
p.T4389A	ACH-002231	Brain Cancer	CCLE	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7139
p.T4389A	D-566MG	central nervous system	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7139
p.V1493I	ACH-002287	Colon/Colorectal Cancer	CCLE	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1944
p.V1493I	NCI-H630	large intestine	COSMIC	PGTTT	DEG_SPOP_SBC_1	1498:1502	Mutation rewiring degron network	0.1944
p.T3165I	ACH-002669	Colon/Colorectal Cancer	CCLE	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation rewiring degron network	0.1111
p.R3885S	RPMI-6666	haematopoietic and lymphoid tissue	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	OV-17R	ovary	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	HPAC	pancreas	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	GCT	soft tissue	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	NCI-H2444	lung	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	U-118-MG	central nervous system	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	U-87-MG	central nervous system	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	HCC202	breast	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.R3885S	EM-2	haematopoietic and lymphoid tissue	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation rewiring degron network	0.1944
p.A4305V	RPMI-6666	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	RPMI-6666	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H1755	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H1755	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	AU565	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	AU565	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	D-423MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	D-423MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	HCC202	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	HCC202	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	HPAC	pancreas	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	HPAC	pancreas	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	SK-MEL-24	skin	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	SK-MEL-24	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H2444	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H2444	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	EM-2	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	EM-2	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	T47D	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	T47D	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	U-118-MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	U-118-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	U-87-MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	U-87-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H1573	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	NCI-H1573	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	BICR78	upper aerodigestive tract	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	BICR78	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	H290	pleura	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	H290	pleura	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	Hs939-T	skin	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	Hs939-T	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.A4305V	RPMI-2650	upper aerodigestive tract	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.1944
p.A4305V	RPMI-2650	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1944
p.P4411L	NCI-H2347	lung	COSMIC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7582
p.P4411L	DBTRG-05MG	central nervous system	COSMIC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7582
p.P4411L	U-CH2	bone	COSMIC	PTATPSST	DEG_SCF_FBW7_1	4407:4414	Mutation altering degron motif	0.7582
p.A2017V	H290	pleura	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	NCI-H2444	lung	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	TOV-21G	ovary	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	HPAC	pancreas	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	KARPAS-299	haematopoietic and lymphoid tissue	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	RPMI-2650	upper aerodigestive tract	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	U-118-MG	central nervous system	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	GCT	soft tissue	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	HCC202	breast	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	CHSA0108	bone	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	BICR78	upper aerodigestive tract	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	D-423MG	central nervous system	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	M059J	central nervous system	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.A2017V	EM-2	haematopoietic and lymphoid tissue	COSMIC	AHTST	DEG_SPOP_SBC_1	2017:2021	Mutation altering degron motif	0.5825
p.T4304N	H290	pleura	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	H290	pleura	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	T47D	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	T47D	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	SK-MEL-24	skin	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	SK-MEL-24	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	D-423MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	D-423MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	RPMI-6666	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	RPMI-6666	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	U-87-MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	U-87-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	NCI-H2444	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	NCI-H2444	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	AU565	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	AU565	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	RPMI-2650	upper aerodigestive tract	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	RPMI-2650	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	HCC202	breast	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	HCC202	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	Hs939-T	skin	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	Hs939-T	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	EM-2	haematopoietic and lymphoid tissue	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	EM-2	haematopoietic and lymphoid tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	U-118-MG	central nervous system	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	U-118-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	HPAC	pancreas	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	HPAC	pancreas	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.T4304N	NCI-H1573	lung	COSMIC	ATSSS	DEG_SPOP_SBC_1	4296:4300	Mutation rewiring degron network	0.2222
p.T4304N	NCI-H1573	lung	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation rewiring degron network	0.1667
p.K4317T	U-118-MG	central nervous system	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	U-118-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.K4317T	HCC202	breast	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	HCC202	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.K4317T	TOV-21G	ovary	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	TOV-21G	ovary	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.K4317T	BICR78	upper aerodigestive tract	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	BICR78	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.K4317T	HCT-15	large intestine	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	HCT-15	large intestine	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.K4317T	GCT	soft tissue	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation substituting flanking lysine	0.2778
p.K4317T	GCT	soft tissue	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation substituting flanking lysine	0.3611
p.S4318P	HCC202	breast	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	HCC202	breast	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	TOV-21G	ovary	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	TOV-21G	ovary	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	M14	skin	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	M14	skin	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	U-118-MG	central nervous system	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	U-118-MG	central nervous system	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	BICR78	upper aerodigestive tract	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	BICR78	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	HCT-15	large intestine	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	HCT-15	large intestine	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.S4318P	RPMI-2650	upper aerodigestive tract	COSMIC	VTPIPS	DEG_SCF_FBW7_1	4323:4328	Mutation blocking phosphorylation signal	0.6389
p.S4318P	RPMI-2650	upper aerodigestive tract	COSMIC	VLTST	DEG_SPOP_SBC_1	4310:4314	Mutation blocking phosphorylation signal	0.6667
p.T3102S	NCI-H835	lung	COSMIC	PSSTPETT	DEG_SCF_FBW7_1	3096:3103	Mutation altering degron motif	0.6005
p.P2659A	CHSA0011	bone	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.2778
p.P2659A	H290	pleura	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.2778
p.T4379R	NCI-H1876	lung	COSMIC	ATSST	DEG_SPOP_SBC_1	4375:4379	Mutation altering degron motif	0.7876
p.T4385P	NB13	autonomic ganglia	COSMIC	PSSTPGTT	DEG_SCF_FBW7_1	4382:4389	Mutation altering degron motif	0.7031
p.T4584I	BICR78	upper aerodigestive tract	COSMIC	VATPSST	DEG_SCF_FBW7_1	4578:4584	Mutation altering degron motif	0.7078
p.T2042I	EM-2	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7078
p.T2042I	U-87-MG	central nervous system	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7078
p.T2042I	HCC202	breast	COSMIC	VATPSST	DEG_SCF_FBW7_1	2036:2042	Mutation altering degron motif	0.7078
p.I2652V	M14	skin	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0833
p.I2652V	OV-17R	ovary	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0833
p.I2652V	HPAC	pancreas	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.0833
p.H2657P	OV-17R	ovary	COSMIC	VLTTT	DEG_SPOP_SBC_1	2661:2665	Mutation rewiring degron network	0.2222
p.S4081F	SK-CO-1	large intestine	COSMIC	PGTTT	DEG_SPOP_SBC_1	4082:4086	Mutation rewiring degron network	0.3056
p.I965L	NCI-H2081	lung	COSMIC	IKLFVE	LIG_APCC_ABBA_1	955:960	Mutation rewiring degron network	0.1944
p.V3875A	A3-KAW	haematopoietic and lymphoid tissue	COSMIC	VTPSSS	DEG_SCF_FBW7_1	3875:3880	Mutation altering degron motif	0.6936
p.P1982A	CHSA0108	bone	COSMIC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation altering degron motif	0.7503
p.P1982A	OE19	oesophagus	COSMIC	VTPIPS	DEG_SCF_FBW7_1	1980:1985	Mutation altering degron motif	0.7503
p.R3288G	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	VATPSST	DEG_SCF_FBW7_1	3293:3299	Mutation rewiring degron network	0.1944
p.R3288G	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	VHTST	DEG_SPOP_SBC_1	3274:3278	Mutation rewiring degron network	0.0556
p.R3288G	KARPAS-422	haematopoietic and lymphoid tissue	COSMIC	VLTTT	DEG_SPOP_SBC_1	3279:3283	Mutation rewiring degron network	0.1944
p.T3153N	SH-4	skin	COSMIC	PTATPSST	DEG_SCF_FBW7_1	3150:3157	Mutation altering degron motif	0.7055

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MUC5B

UniProt ID: Q9HC84

Entrez ID: 727897

Protein name: Mucin-5B (MUC-5B) (Cervical mucin) (High molecular weight salivary mucin MG1) (Mucin-5 subtype B, tracheobronchial) (Sublingual gland mucin)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MUC5B in