DegronMD

Uniprot ID: Q9HC84

Source protein: Mucin-5B

Source gene: MUC5B

Class: DEG_SCF_FBW7_1

Location: 3963:3970

E3 ligase: FBXW7

DEGRON score: 0.9055

ASA_SCORE: 90.8875

COIL: 0.9685

CONS_SCORE: 0.309

DSS_SCORE: 0.6859

HELIX: 0.0086

FCONS_SCORE: 1.0483

RIG_SCORE: 0.597

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.T3955M	TCGA-AJ-A3EL	UCEC	TCGA	PSSTPGTT	DEG_SCF_FBW7_1	0.1111
p.N3965T	DO219879	SKCA	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	0.7055
p.T3958M	DO41542	UCEC	ICGC	PSSTPGTT	DEG_SCF_FBW7_1	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons