DegronMD

Uniprot ID: Q9HC84

Source protein: Mucin-5B

Source gene: MUC5B

Class: DEG_SCF_FBW7_1

Location: 3374:3380

E3 ligase: FBXW7

DEGRON score: 0.9863

ASA_SCORE: 93.0857

COIL: 0.9519

CONS_SCORE: 0.3139

DSS_SCORE: 0.6324

HELIX: 0.0159

FCONS_SCORE: 1.0893

RIG_SCORE: 0.659

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P3388L	TCGA-C5-A8XJ	CESC	TCGA	MATPSSS	DEG_SCF_FBW7_1	0.1111
p.S3382C	DO229268	THCA	ICGC	MATPSSS	DEG_SCF_FBW7_1	0.2778
p.P3388Q	ACH-000198	Leukemia	CCLE	MATPSSS	DEG_SCF_FBW7_1	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons