p.D798Y | TCGA-05-4427 | LUAD | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation altering degron motif | 0.6214 |
p.L797F | TCGA-05-4427 | LUAD | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.R660S | TCGA-05-5425 | LUAD | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0556 |
p.R660S | DO26270 | LUAD | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0556 |
p.G659R | TCGA-05-5425 | LUAD | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.G659R | DO26270 | LUAD | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.P788S | TCGA-18-3409 | LUSC | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0556 |
p.E814Q | TCGA-29-1777 | OV | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1111 |
p.G283A | TCGA-78-7220 | LUAD | TCGA | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1944 |
p.G283A | DO24409 | LUAD | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1944 |
p.L358F | TCGA-A5-A0G1 | UCEC | TCGA | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6981 |
p.L358F | DO42472 | UCEC | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6981 |
p.E546K | TCGA-A5-A0G2 | UCEC | TCGA | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.1667 |
p.E546K | DO41235 | UCEC | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.1667 |
p.R577K | TCGA-A5-A2K5 | UCEC | TCGA | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1944 |
p.S609F | TCGA-AC-A23C | BRCA | TCGA | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation blocking phosphorylation signal | 0.75 |
p.S609F | DO3626 | BRCA | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation blocking phosphorylation signal | 0.75 |
p.L358V | TCGA-AG-3592 | READ | TCGA | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6765 |
p.L358V | DO37308 | READ | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6765 |
p.R299Q | TCGA-AG-3902 | READ | TCGA | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1389 |
p.R299Q | DO36407 | READ | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1389 |
p.R299Q | SIDM01608 | Endometrial Carcinoma | GDSC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1389 |
p.R299Q | ACH-000990 | Endometrial/Uterine Cancer | CCLE | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1389 |
p.R585W | TCGA-AP-A1DV | UCEC | TCGA | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation altering degron motif | 0.7523 |
p.R585W | DO43186 | UCEC | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation altering degron motif | 0.7523 |
p.A622V | TCGA-AX-A2HD | UCEC | TCGA | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.1944 |
p.A622V | DO42608 | UCEC | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.1944 |
p.R363Q | TCGA-B5-A0JY | UCEC | TCGA | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.3056 |
p.R363Q | DO43041 | UCEC | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.3056 |
p.R363Q | SIDM01611 | Endometrial Carcinoma | GDSC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.3056 |
p.R363Q | ACH-000996 | Endometrial/Uterine Cancer | CCLE | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.3056 |
p.G283W | TCGA-B5-A0JY | UCEC | TCGA | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1944 |
p.P614L | TCGA-B5-A3FA | UCEC | TCGA | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation altering degron motif | 0.7582 |
p.P614L | DO52402 | UCEC | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation altering degron motif | 0.7582 |
p.G607W | TCGA-BF-A1PZ | SKCM | TCGA | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.25 |
p.G607W | DO50279 | SKCM | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.25 |
p.R594W | TCGA-CG-5723 | STAD | TCGA | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.2222 |
p.R594W | DO38376 | STAD | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.2222 |
p.D557N | TCGA-CR-7395 | HNSC | TCGA | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation altering degron motif | 0.5821 |
p.D557N | DO14274 | HNSC | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation altering degron motif | 0.5821 |
p.R577M | TCGA-D3-A2JC | SKCM | TCGA | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1944 |
p.G659E | TCGA-D3-A3C1 | SKCM | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.G659E | DO47323 | SKCM | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.T549S | TCGA-D7-A6EY | STAD | TCGA | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.25 |
p.T549S | DO50118 | STAD | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.25 |
p.G362W | TCGA-DA-A1I1 | SKCM | TCGA | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6714 |
p.L808P | TCGA-DM-A1HB | COAD | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.2778 |
p.F575L | TCGA-DU-6392 | LGG | TCGA | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1389 |
p.F575L | DO22237 | LGG | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1389 |
p.F575L | SIDM01611 | Endometrial Carcinoma | GDSC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1389 |
p.F575L | ACH-000996 | Endometrial/Uterine Cancer | CCLE | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1389 |
p.G659W | TCGA-EE-A181 | SKCM | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.G659W | DO37444 | SKCM | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.G659V | TCGA-EE-A2GR | SKCM | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.G659V | DO37996 | SKCM | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0833 |
p.E814D | TCGA-EO-A3B0 | UCEC | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1111 |
p.P646Q | TCGA-ER-A1A1 | SKCM | TCGA | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation altering degron motif | 0.7035 |
p.P646Q | DO37413 | SKCM | ICGC | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation altering degron motif | 0.7035 |
p.N547H | TCGA-EY-A1GI | UCEC | TCGA | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.1944 |
p.N547H | DO41211 | UCEC | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.1944 |
p.P816L | TCGA-FG-A6J3 | LGG | TCGA | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0556 |
p.E816K | DO1780 | BRCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0556 |
p.E278K | DO3346 | BRCA | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.0556 |
p.E361K | DO5507 | BRCA | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.7022 |
p.G815E | DO10276 | COAD | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0833 |
p.N561H | DO222884 | COCA | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.3056 |
p.L800P | DO52450 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation altering degron motif | 0.7582 |
p.V811I | DO229010 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |
p.V811I | DO229013 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |
p.V811I | DO229016 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |
p.V811I | DO229003 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |
p.V811I | DO229005 | COCA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |
p.P619L | DO234285 | ESAD | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.2778 |
p.L285R | DO233129 | GACA | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation blocking phosphorylation signal | 0.6944 |
p.Q347E | DO233267 | GACA | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.1389 |
p.G815V | DO14926 | HNSC | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0833 |
p.E367D | DO52066 | HNSC | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.1944 |
p.P808L | DO44538 | LGG | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.2778 |
p.N367K | DO228948 | LICA | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.1944 |
p.L598I | DO228985 | LICA | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1111 |
p.P606T | DO229019 | LICA | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.2222 |
p.L795M | DO229028 | LICA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.25 |
p.T290N | DO229024 | LICA | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation altering degron motif | 0.7055 |
p.L586I | DO229026 | LICA | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation altering degron motif | 0.7174 |
p.N596K | DO229036 | LICA | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation rewiring degron network | 0.1667 |
p.N792K | DO229041 | LICA | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1667 |
p.I280M | DO231636 | LINC | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1111 |
p.D359Y | DO218922 | LUAD | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.7325 |
p.D790Y | DO23666 | LUAD | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1111 |
p.L789F | DO23666 | LUAD | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation blocking phosphorylation signal | 0.5278 |
p.K562R | DO220876 | MELA | ICGC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.2778 |
p.D359N | DO222683 | MELA | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6932 |
p.D359N | DO37417 | SKCM | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.6932 |
p.E297K | DO222880 | MELA | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1944 |
p.A288S | DO27939 | ORCA | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation altering degron motif | 0.7588 |
p.W623S | DO46493 | OV | ICGC | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.1667 |
p.E806Q | DO28071 | OV | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation altering degron motif | 0.6744 |
p.C357S | DO34136 | PACA | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation altering degron motif | 0.7541 |
p.R585Q | DO228138 | PBCA | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation altering degron motif | 0.6218 |
p.R585G | DO233487 | PRAD | ICGC | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation altering degron motif | 0.6457 |
p.G815W | DO47442 | SKCM | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.0833 |
p.V345A | DO47903 | STAD | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.0833 |
p.E806D | DO219773 | UCEC | ICGC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation altering degron motif | 0.6758 |
p.M296I | DO43065 | UCEC | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.2222 |
p.K365E | DO43154 | UCEC | ICGC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.25 |
p.C298Y | DO43747 | UCEC | ICGC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1667 |
p.G279C | SIDM00338 | Acute Myeloid Leukemia | GDSC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.0833 |
p.G279C | ACH-000439 | Leukemia | CCLE | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.0833 |
p.G279C | ME-1 | haematopoietic and lymphoid tissue | COSMIC | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.0833 |
p.K564N | SIDM01198 | Burkitt's Lymphoma | GDSC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation substituting flanking lysine | 0.3333 |
p.K564N | ACH-000567 | Lymphoma | CCLE | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation substituting flanking lysine | 0.3333 |
p.K564N | ST486 | haematopoietic and lymphoid tissue | COSMIC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation substituting flanking lysine | 0.3333 |
p.H345P | SIDM00060 | Ovarian Carcinoma | GDSC | NRTMLFQVG | DEG_APCC_DBOX_1 | 354:362 | Mutation rewiring degron network | 0.0833 |
p.S542G | SIDM01039 | Other Solid Cancers | GDSC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.0556 |
p.S542G | JAR | placenta | COSMIC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.0556 |
p.P807T | SIDM00596 | Endometrial Carcinoma | GDSC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.P807T | ACH-000941 | Endometrial/Uterine Cancer | CCLE | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.P807T | ACH-000954 | Endometrial/Uterine Cancer | CCLE | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.P807T | ACH-001517 | Endometrial/Uterine Cancer | CCLE | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.P807T | HEC-1 | endometrium | COSMIC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.3056 |
p.K564R | SIDM00975 | Melanoma | GDSC | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation substituting flanking lysine | 0.3333 |
p.N655H | ACH-000774 | Lung Cancer | CCLE | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.1944 |
p.N547S | ACH-001063 | Ovarian Cancer | CCLE | GRFKLDILK | DEG_APCC_DBOX_1 | 552:560 | Mutation rewiring degron network | 0.1944 |
p.R639W | ACH-001369 | Ovarian Cancer | CCLE | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.1389 |
p.S597R | ACH-001389 | Breast Cancer | CCLE | MRGRLGSVD | DEG_APCC_DBOX_1 | 582:590 | Mutation blocking phosphorylation signal | 0.5833 |
p.T625M | ACH-001688 | Kidney Cancer | CCLE | PPGTPPAS | DEG_SCF_FBW7_1 | 610:617 | Mutation rewiring degron network | 0.1111 |
p.R660M | ACH-001692 | Head and Neck Cancer | CCLE | PPSST | DEG_SPOP_SBC_1 | 646:650 | Mutation rewiring degron network | 0.0556 |
p.R299W | ACH-001735 | Leukemia | CCLE | ALTSS | DEG_SPOP_SBC_1 | 288:292 | Mutation rewiring degron network | 0.1389 |
p.P799T | HEC-1 | endometrium | COSMIC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation altering degron motif | 0.7031 |
p.M793I | LU-165 | lung | COSMIC | DRNELLPLS | DEG_APCC_DBOX_1 | 798:806 | Mutation rewiring degron network | 0.1944 |