DegronMD - Q06455(RUNX1T1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R212K	TCGA-06-5416	GBM	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0833
p.T91M	TCGA-28-5216	GBM	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.R61G	TCGA-34-5234	LUSC	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1944
p.P64H	TCGA-43-5670	LUSC	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.2778
p.G100S	TCGA-50-5930	LUAD	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.3056
p.T387N	TCGA-75-7031	LUAD	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.Q571R	TCGA-77-7465	LUSC	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2778
p.P71L	TCGA-85-8287	LUSC	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.3056
p.P599L	TCGA-A5-AB3J	UCEC	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1111
p.P599L	TCGA-A5-AB3J	UCEC	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1389
p.P599L	TCGA-AC-A8OP	BRCA	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1111
p.P599L	TCGA-AC-A8OP	BRCA	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1389
p.Q570K	TCGA-AG-4009	READ	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.3056
p.T582M	TCGA-AJ-A2QK	UCEC	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.2778
p.T582M	TCGA-AJ-A2QK	UCEC	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1667
p.K366T	TCGA-AP-A056	UCEC	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1944
p.E363G	TCGA-AP-A0LM	UCEC	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.A211T	TCGA-AP-A0LM	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.A211T	TCGA-AP-A1DK	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.A211T	TCGA-AZ-4315	COAD	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.A211T	TCGA-E9-A22D	BRCA	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.A211T	TCGA-XK-AAIW	PRAD	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.H225R	TCGA-AX-A05Y	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation altering degron motif	0.8244
p.A232T	TCGA-AZ-6601	COAD	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1389
p.E556D	TCGA-BS-A0UV	UCEC	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0833
p.T598S	TCGA-CN-A63T	HNSC	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.T598S	TCGA-CN-A63T	HNSC	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1667
p.N99S	TCGA-CR-6480	HNSC	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2778
p.H370Y	TCGA-D3-A5GS	SKCM	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.3056
p.T66S	TCGA-D5-5539	COAD	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7116
p.S114Y	TCGA-DF-A2KV	UCEC	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0833
p.Y221C	TCGA-DI-A1BU	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation altering degron motif	0.7087
p.A97D	TCGA-DM-A28G	COAD	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.P70L	TCGA-EB-A5UN	SKCM	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7582
p.Q569K	TCGA-EE-A17Z	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.6944
p.E363K	TCGA-EE-A20C	SKCM	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.D369N	TCGA-EE-A29G	SKCM	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2778
p.D573E	TCGA-EE-A2A0	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.D377G	TCGA-EI-6917	READ	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7198
p.R78I	TCGA-EO-A22X	UCEC	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.A232V	TCGA-F4-6703	COAD	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1389
p.M378I	TCGA-F7-7848	HNSC	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7618
p.A219V	TCGA-FI-A2D5	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2778
p.A219V	LCLC-103H	lung	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2778
p.Q570L	TCGA-FS-A1ZW	SKCM	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.3056
p.G111R	TCGA-GS-A9TY	DLBC	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1667
p.V388I	TCGA-HU-8602	STAD	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0833
p.V388I	SNU-C2B	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0833
p.P112S	TCGA-K7-A5RF	LIHC	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.W361R	TCGA-L9-A7SV	LUAD	TCGA	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0556
p.P595Q	TCGA-O2-A52S	LUSC	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation blocking phosphorylation signal	0.6667
p.P595Q	TCGA-O2-A52S	LUSC	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation blocking phosphorylation signal	0.6944
p.S94C	TCGA-OD-A75X	SKCM	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.Q220L	TCGA-QQ-A5VD	SARC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.3056
p.A214V	TCGA-SL-A6JA	UCEC	TCGA	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1389
p.P575T	TCGA-T3-A92N	HNSC	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0833
p.P575T	TCGA-T3-A92N	HNSC	TCGA	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1667
p.P68S	TCGA-VQ-AA6D	STAD	TCGA	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.6752
p.S580F	TCGA-W3-A825	SKCM	TCGA	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.2222
p.S580F	TCGA-W3-A825	SKCM	TCGA	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1111
p.S115C	TCGA-XF-AAN4	BLCA	TCGA	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.S383R	DO48447	BLCA	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.S67C	DO51943	BLCA	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7541
p.E211K	DO48566	BLCA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO514	BLCA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO14196	HNSC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO222434	MELA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO27943	ORCA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO37579	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO37851	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO37406	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO47343	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.E211K	DO223907	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.P561L	DO50032	BRCA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.P561L	DO223280	UCEC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.T221N	DO219592	BRCA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation altering degron motif	0.7055
p.E106K	DO222421	BTCA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.3056
p.W365C	DO10300	COAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1667
p.R367W	DO7972	COAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.R367W	DO26444	LUSC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.R367W	DO36766	READ	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.R367W	DO222332	STAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.R367W	SNU-175	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.R112H	DO9876	COAD	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.R112H	DO22155	LGG	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.R112H	DO37551	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.R112H	DO43186	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.N212D	DO8264	COAD	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0833
p.R577H	DO230347	COCA	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577H	DO230347	COCA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.R577H	DO228138	PBCA	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577H	DO228138	PBCA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.R577H	DO232761	PBCA	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577H	DO232761	PBCA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.L96M	DO230346	COCA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.R368Q	DO227976	COCA	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.25
p.R368Q	DO224688	PACA	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.25
p.G63R	DO219917	DLBC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.25
p.R216Q	DO234219	ESAD	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO10880	GBM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO26444	LUSC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO37839	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO37406	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO47401	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO51276	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO43202	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.R216Q	DO41542	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.Q75P	DO234346	ESAD	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1944
p.R577C	DO234461	ESAD	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577C	DO234461	ESAD	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.R577C	DO22237	LGG	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577C	DO22237	LGG	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.T95I	DO228494	GACA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1667
p.T560S	DO49040	HNSC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.H385N	DO49040	HNSC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1667
p.P56Q	DO229022	LICA	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.D374E	DO229027	LICA	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.6758
p.D102E	DO229032	LICA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.6758
p.D102E	DO26668	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.6758
p.P57R	DO44668	LICA	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0833
p.S381N	DO52318	LIHC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2778
p.P64S	DO52303	LIHC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.2778
p.P64S	DO23130	LINC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.2778
p.S68F	DO52241	LIHC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7982
p.S68F	DO38105	SKCM	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7982
p.S68F	Sarc9371	bone	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7982
p.S66P	DO23104	LINC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.6752
p.G63W	DO231719	LINC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.25
p.S383T	DO45047	LINC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.E109K	DO229177	LMS	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.E109K	DO222753	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.E109K	TE-11	oesophagus	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.R91S	DO25659	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.R91S	DO24487	LUAD	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.P566Q	DO23717	LUAD	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7035
p.L362S	DO45323	LUAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0833
p.G378C	DO51193	LUAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.76
p.A80S	DO230929	LUSC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.A80S	DO224572	LUSC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.L114I	DO231152	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0833
p.P566T	DO26530	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7031
p.R228I	DO50097	LUSC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.R216L	DO26772	LUSC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1944
p.S381I	DO26713	LUSC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2778
p.R577S	DO45492	LUSC	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.R577S	DO45492	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.T95A	DO45452	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1667
p.T95A	BT-474	breast	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1667
p.T95N	DO223719	LUSC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1667
p.E229D	DO27349	LUSC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2222
p.E573K	DO219151	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.E573K	DO37856	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.P557Q	DO219221	LUSC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.R91K	DO220855	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.S65F	DO220879	MELA	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.3056
p.G213W	DO220877	MELA	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1111
p.E373K	DO220891	MELA	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7022
p.R112C	DO220899	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.R112C	DO219464	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.R112C	DO41235	UCEC	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.P576L	DO220906	MELA	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1111
p.P576L	DO220906	MELA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1389
p.P576L	DO42713	UCEC	ICGC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1111
p.P576L	DO42713	UCEC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1389
p.R110K	DO222868	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.P78L	DO229149	NKTL	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.A558P	DO34208	PACA	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1389
p.A372T	DO51407	PRAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7139
p.A372T	DO40996	UCEC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7139
p.A372T	SNU-175	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7139
p.S104L	DO37551	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.7667
p.G567R	DO37429	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7568
p.G567R	DO47537	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7568
p.R220K	DO37406	SKCM	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.3056
p.R110G	DO50291	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.D371N	DO50284	SKCM	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.6932
p.P569S	DO48665	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.6752
p.T113I	DO38105	SKCM	ICGC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1111
p.P566L	DO51271	SKCM	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7582
p.S386F	DO51291	SKCM	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1389
p.R367Q	DO48547	STAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.G225D	DO38747	STAD	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation altering degron motif	0.7198
p.R368W	DO38743	STAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.25
p.R368W	UDSCC2	upper aerodigestive tract	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.25
p.G380D	DO47867	STAD	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.3056
p.S69P	DO229259	THCA	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.6752
p.S66Y	DO219771	UCEC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.712
p.S381C	DO42320	UCEC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2778
p.S71Y	DO43202	UCEC	ICGC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.3056
p.R220S	DO41758	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.3056
p.G378R	DO41927	UCEC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7568
p.E373D	DO41235	UCEC	ICGC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.6758
p.E373D	TE-4	oesophagus	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.6758
p.T571I	DO41235	UCEC	ICGC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2778
p.R215M	DO42592	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.1667
p.E211A	DO42713	UCEC	ICGC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.R109W	SIDM02049	Pancreatic Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.A560T	SIDM02015	Colorectal Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.T220K	SIDM01265	Plasma Cell Myeloma	GDSC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.3056
p.T220K	MM1S	haematopoietic and lymphoid tissue	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.3056
p.H379Q	SIDM00680	Colorectal Carcinoma	GDSC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7582
p.H379Q	LS-180	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7582
p.L110M	SIDM00057	Neuroblastoma	GDSC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.L110M	ACN	autonomic ganglia	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.S573R	SIDM00155	Head and Neck Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.S573R	PCI-38	upper aerodigestive tract	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.2222
p.T106K	SIDM00807	Bladder Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.3056
p.T106K	5637	urinary tract	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.3056
p.T91A	SIDM01608	Endometrial Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.D559E	SIDM00015	Esophageal Squamous Cell Carcinoma	GDSC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1667
p.P59A	ACH-000188	Head and Neck Cancer	CCLE	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1389
p.P59A	SCC-25	upper aerodigestive tract	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1389
p.T80K	ACH-000236	Colon/Colorectal Cancer	CCLE	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.T80K	SW1417	large intestine	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0556
p.S574I	ACH-000438	Lung Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.S574I	ACH-000438	Lung Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.S574I	LU-65	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.S574I	LU-65	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.P58L	ACH-000510	Lung Cancer	CCLE	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.P58L	NCI-H1299	lung	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.P593Q	ACH-000672	Lung Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.2778
p.P593Q	ACH-000672	Lung Cancer	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.3056
p.S567R	ACH-000744	Lung Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7427
p.S567R	NCI-H1623	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7427
p.G79V	ACH-000790	Lung Cancer	CCLE	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0833
p.G79V	SHP-77	lung	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.0833
p.L217M	ACH-000825	Lung Cancer	CCLE	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2222
p.L217M	HOP-92	lung	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2222
p.T601P	ACH-000842	Colon/Colorectal Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.T601P	ACH-000842	Colon/Colorectal Cancer	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.0833
p.G96V	ACH-000851	Lung Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1944
p.M580I	ACH-000881	Skin Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.2222
p.M580I	ACH-000881	Skin Cancer	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1111
p.M580I	MEL-JUSO	skin	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.2222
p.M580I	MEL-JUSO	skin	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1111
p.S574R	ACH-000951	Lung Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.S574R	ACH-000951	Lung Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.S574R	NCI-H2342	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.S574R	NCI-H2342	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.P579Q	ACH-000955	Colon/Colorectal Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1944
p.P579Q	ACH-000955	Colon/Colorectal Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0556
p.P579Q	ACH-000955	Colon/Colorectal Cancer	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.0833
p.P579Q	SNU-407	large intestine	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1944
p.P579Q	SNU-407	large intestine	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0556
p.P579Q	SNU-407	large intestine	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.0833
p.R386Q	ACH-000960	Leukemia	CCLE	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1389
p.R386Q	REH	haematopoietic and lymphoid tissue	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1389
p.V377I	ACH-000967	Colon/Colorectal Cancer	CCLE	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.5965
p.V377I	ACH-001199	Colon/Colorectal Cancer	CCLE	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.5965
p.V377I	SNU-C2B	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.5965
p.E387G	ACH-000978	Endometrial/Uterine Cancer	CCLE	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.E387G	EN	endometrium	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.Q558R	ACH-000983	Leukemia	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1389
p.Q558R	KCL-22	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1389
p.S574N	ACH-000985	Colon/Colorectal Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0556
p.S574N	ACH-000985	Colon/Colorectal Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.R67I	ACH-000993	Endometrial/Uterine Cancer	CCLE	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.6991
p.T591A	ACH-000995	Leukemia	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.825
p.T591A	ACH-000995	Leukemia	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation altering degron motif	0.825
p.P583Q	ACH-000998	Colon/Colorectal Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.3056
p.P583Q	ACH-000998	Colon/Colorectal Cancer	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1944
p.G577R	ACH-001136	Lung Cancer	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.G577R	ACH-001136	Lung Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.G577R	NCI-H187	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1389
p.G577R	NCI-H187	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.L218F	ACH-001199	Colon/Colorectal Cancer	CCLE	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.L218F	SNU-C2B	large intestine	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.S106F	ACH-001570	Skin Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.3056
p.V566L	ACH-001622	Brain Cancer	CCLE	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.5654
p.E600G	ACH-001991	Primary	CCLE	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.0833
p.E600G	ACH-001991	Primary	CCLE	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1111
p.V227L	ACH-002302	Leukemia	CCLE	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2778
p.V227L	RPMI-8866	haematopoietic and lymphoid tissue	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2778
p.S105F	ACH-002396	Bone Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.7982
p.S105F	Sarc9371	bone	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.7982
p.E211G	SNU-81	large intestine	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.0556
p.P69L	NCI-H1299	lung	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7582
p.P384T	NCI-H1573	lung	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1944
p.S104G	PANC-08-13	pancreas	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.6993
p.T105A	BT-474	breast	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation altering degron motif	0.7139
p.D371G	OVCAR-3	ovary	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7198
p.P218L	SW684	soft tissue	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.A362T	SNU-175	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0833
p.P559Q	SNU-407	large intestine	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1667
p.R366Q	REH	haematopoietic and lymphoid tissue	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1944
p.S78F	Sarc9371	bone	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.S227R	STS-0421	soft tissue	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2778
p.S97G	PANC-08-13	pancreas	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.2222
p.S585R	NCI-H2342	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.7427
p.A379T	SNU-175	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7139
p.G59V	SHP-77	lung	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1389
p.D361G	OVCAR-3	ovary	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0556
p.E363D	TE-4	oesophagus	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.1111
p.D378G	OVCAR-3	ovary	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.7198
p.L229F	SNU-C2B	large intestine	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.2222
p.R375W	UDSCC2	upper aerodigestive tract	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.8634
p.L228M	HOP-92	lung	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.V368A	LNCaP-Clone-FGC	prostate	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.25
p.M591I	MEL-JUSO	skin	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.7618
p.M591I	MEL-JUSO	skin	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation altering degron motif	0.7618
p.A388V	NCI-H1915	lung	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.0833
p.S578R	NCI-H1623	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.1667
p.S578R	NCI-H1623	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.0833
p.S578R	NCI-H1623	lung	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.0556
p.G588R	NCI-H187	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.7568
p.G588R	NCI-H187	lung	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation altering degron motif	0.7568
p.P590Q	SNU-407	large intestine	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.7035
p.P590Q	SNU-407	large intestine	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation altering degron motif	0.7035
p.T91K	SW1417	large intestine	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.0556
p.S585I	LU-65	lung	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation altering degron motif	0.7341
p.T60K	SW1417	large intestine	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1667
p.E218G	SNU-81	large intestine	COSMIC	ASTTS	DEG_SPOP_SBC_1	221:225	Mutation rewiring degron network	0.25
p.P70A	SCC-25	upper aerodigestive tract	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation altering degron motif	0.7503
p.T112A	BT-474	breast	COSMIC	PSSSS	DEG_SPOP_SBC_1	101:105	Mutation rewiring degron network	0.1389
p.N383K	HOP-92	lung	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.V379A	LNCaP-Clone-FGC	prostate	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.6936
p.R374W	SNU-175	large intestine	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation altering degron motif	0.8634
p.T58K	5637	urinary tract	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.1111
p.L62M	ACN	autonomic ganglia	COSMIC	PRTSS	DEG_SPOP_SBC_1	66:70	Mutation rewiring degron network	0.2222
p.M560I	MEL-JUSO	skin	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1944
p.E367G	EN	endometrium	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.2222
p.E583K	Sarc9371	bone	COSMIC	PAATPRST	DEG_SCF_FBW7_1	584:591	Mutation rewiring degron network	0.3056
p.E583K	Sarc9371	bone	COSMIC	PRSTT	DEG_SPOP_SBC_1	588:592	Mutation rewiring degron network	0.1944
p.E380D	TE-4	oesophagus	COSMIC	TRRSLTVLR	DEG_APCC_DBOX_1	371:379	Mutation rewiring degron network	0.3056
p.G557R	NCI-H187	lung	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation rewiring degron network	0.1111
p.Q569R	KCL-22	haematopoietic and lymphoid tissue	COSMIC	AVSSS	DEG_SPOP_SBC_1	565:569	Mutation altering degron motif	0.7329

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RUNX1T1

UniProt ID: Q06455

Entrez ID: 862

Protein name: Protein CBFA2T1 (Cyclin-D-related protein) (Eight twenty one protein) (Protein ETO) (Protein MTG8) (Zinc finger MYND domain-containing protein 2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RUNX1T1 in