DegronMD - Q14517(FAT1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D3075Y	TCGA-19-5956	GBM	TCGA	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation altering degron motif	0.7325
p.D3075Y	DO13863	GBM	ICGC	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation altering degron motif	0.7325
p.D1278N	TCGA-2G-AAKD	TGCT	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	TCGA-A5-A1OF	UCEC	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	TCGA-EB-A551	SKCM	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	DO47453	SKCM	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	DO42568	UCEC	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	SIDM00193	Colorectal Carcinoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	ACH-000991	Colon/Colorectal Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.D1278N	SNU-81	large intestine	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.25
p.T1179S	TCGA-56-7731	LUSC	TCGA	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.T1179S	DO45527	LUSC	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.0833
p.Y4519S	TCGA-64-5775	LUAD	TCGA	PPGY	ITCH	4520:4523	Mutation blocking phosphorylation signal	0.75
p.Y4519S	DO26025	LUAD	ICGC	PPGY	ITCH	4520:4523	Mutation blocking phosphorylation signal	0.75
p.A1163S	TCGA-75-5146	LUAD	TCGA	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.A1163S	DO25228	LUAD	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.L940I	TCGA-77-7141	LUSC	TCGA	PPNY	ITCH	929:932	Mutation rewiring degron network	0.1111
p.L940I	DO26450	LUSC	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.1111
p.A1163P	TCGA-77-A5GH	LUSC	TCGA	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.A1163P	DO45452	LUSC	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation rewiring degron network	0.25
p.P4520Q	TCGA-78-8662	LUAD	TCGA	PPGY	ITCH	4520:4523	Mutation altering degron motif	0.7035
p.P4520Q	DO45346	LUAD	ICGC	PPGY	ITCH	4520:4523	Mutation altering degron motif	0.7035
p.A3067T	TCGA-A5-A0G2	UCEC	TCGA	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation rewiring degron network	0.1667
p.A3067T	DO41235	UCEC	ICGC	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation rewiring degron network	0.1667
p.A4531T	TCGA-A5-A1OF	UCEC	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1111
p.A4531T	DO42568	UCEC	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1111
p.A4531T	SIDM01146	Gastric Carcinoma	GDSC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1111
p.A4531T	NCI-SNU-1	stomach	COSMIC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1111
p.A1285T	TCGA-A6-3809	COAD	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.A1285T	DO8722	COAD	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.H4516Y	TCGA-A6-6138	COAD	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2222
p.H4516Y	DO10427	COAD	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2222
p.S4375L	TCGA-AP-A1DV	UCEC	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.S4375L	TCGA-EE-A29R	SKCM	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.S4375L	DO232761	PBCA	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.S4375L	DO37448	SKCM	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.S4375L	DO43186	UCEC	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.V1274I	TCGA-AP-A1DV	UCEC	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	TCGA-AZ-6598	COAD	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	DO10276	COAD	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	DO43186	UCEC	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	SIDM00032	Bladder Carcinoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	ACH-000839	Bladder Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.V1274I	ACH-000872	Lung Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.5965
p.F927C	TCGA-AX-A0J0	UCEC	TCGA	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2778
p.F927C	DO41133	UCEC	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2778
p.G4522W	TCGA-AX-A2HJ	UCEC	TCGA	PPGY	ITCH	4520:4523	Mutation altering degron motif	0.6714
p.G4522W	DO42105	UCEC	ICGC	PPGY	ITCH	4520:4523	Mutation altering degron motif	0.6714
p.L3072P	TCGA-AY-6197	COAD	TCGA	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation rewiring degron network	0.3056
p.L3072P	DO9956	COAD	ICGC	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation rewiring degron network	0.3056
p.E4533K	TCGA-B5-A0JY	UCEC	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.0556
p.E4533K	DO43041	UCEC	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.0556
p.D4244H	TCGA-B9-A69E	KIRP	TCGA	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.6577
p.D4244H	DO44513	KIRP	ICGC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.6577
p.P4518S	TCGA-BF-AAP1	SKCM	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2778
p.P4518S	DO219464	SKCM	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2778
p.R1262Q	TCGA-CD-A4MI	STAD	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.R1262Q	DO47717	STAD	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.P925R	TCGA-CR-7379	HNSC	TCGA	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2222
p.P925R	DO14174	HNSC	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2222
p.F4371L	TCGA-CX-7085	HNSC	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1944
p.F4371L	DO14758	HNSC	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1944
p.S4367C	TCGA-CX-7085	HNSC	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.3056
p.S4367C	DO14758	HNSC	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.3056
p.R933H	TCGA-D1-A2G0	UCEC	TCGA	PPNY	ITCH	929:932	Mutation rewiring degron network	0.3056
p.R933H	DO231899	NBL	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.3056
p.R933H	DO43049	UCEC	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.3056
p.Q4248H	TCGA-DF-A2KN	UCEC	TCGA	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.2778
p.Q4248H	DO223282	UCEC	ICGC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.2778
p.R1268W	TCGA-DU-6392	LGG	TCGA	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.8634
p.R1268W	DO22237	LGG	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.8634
p.R1268W	DO228346	MALY	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.8634
p.E4374K	TCGA-EI-6917	READ	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1111
p.E4374K	DO36881	READ	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1111
p.H4516N	TCGA-ER-A19B	SKCM	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2222
p.H4516N	DO47491	SKCM	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.2222
p.P4515L	TCGA-FW-A3R5	SKCM	TCGA	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1944
p.P4515L	DO37406	SKCM	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1944
p.D2349Y	TCGA-IB-7651	PAAD	TCGA	VDSST	DEG_SPOP_SBC_1	2335:2339	Mutation rewiring degron network	0.0556
p.D2349Y	DO46657	PAAD	ICGC	VDSST	DEG_SPOP_SBC_1	2335:2339	Mutation rewiring degron network	0.0556
p.S4373F	TCGA-JX-A3Q0	CESC	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1389
p.S4373F	DO51607	CESC	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.1389
p.V920I	TCGA-L5-A8NI	ESCA	TCGA	PPNY	ITCH	929:932	Mutation rewiring degron network	0.0833
p.G3077C	TCGA-SL-A6JA	UCEC	TCGA	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation altering degron motif	0.76
p.G3077C	DO219787	UCEC	ICGC	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation altering degron motif	0.76
p.S4367F	TCGA-W3-AA1W	SKCM	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.3056
p.S4367F	DO51277	SKCM	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.3056
p.E4364K	TCGA-ZF-A9RC	BLCA	TCGA	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation altering degron motif	0.591
p.E4364K	DO219068	BLCA	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation altering degron motif	0.591
p.H1273R	DO229010	COCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO229013	COCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO229016	COCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO229003	COCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO229005	COCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO229480	LAML	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO231114	LUSC	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.H1273R	DO233575	RECA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.7133
p.R1257Q	DO223038	ESCA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.R1257Q	SIDM00328	Esophageal Squamous Cell Carcinoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.R1257Q	SIDM01526	Mesothelioma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.R1257Q	ACH-000086	Lung Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.R1257Q	ACH-000605	Esophageal Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.R1257Q	TE-6	oesophagus	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0556
p.I4245M	DO233737	GACA	ICGC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.6507
p.S1168A	DO231988	LICA	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.7588
p.S2337R	DO228948	LICA	ICGC	VDSST	DEG_SPOP_SBC_1	2335:2339	Mutation altering degron motif	0.7427
p.A1276D	DO229029	LICA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.A1266D	DO229031	LICA	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.P1270A	DO231070	LUSC	ICGC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.6392
p.Y4356H	DO27851	MALY	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation blocking phosphorylation signal	0.7222
p.E4533D	DO228550	MALY	ICGC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.0556
p.D2349N	DO52658	MALY	ICGC	VDSST	DEG_SPOP_SBC_1	2335:2339	Mutation rewiring degron network	0.0556
p.P925S	DO222516	MELA	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2222
p.P4246L	DO222546	MELA	ICGC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.7582
p.R3087C	DO222731	MELA	ICGC	NPDTGE	DEG_Kelch_Keap1_1	3073:3078	Mutation rewiring degron network	0.0833
p.D1167Y	DO232013	ORCA	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation altering degron motif	0.6214
p.F927Y	DO46755	PAEN	ICGC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.2778
p.Y1176H	DO228138	PBCA	ICGC	PDSSS	DEG_SPOP_SBC_1	1166:1170	Mutation blocking phosphorylation signal	0.6111
p.N2325S	DO36556	READ	ICGC	VDSST	DEG_SPOP_SBC_1	2335:2339	Mutation rewiring degron network	0.0556
p.Q4366H	DO229253	THCA	ICGC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation altering degron motif	0.647
p.A1276V	SIDM01259	B-Lymphoblastic Leukemia	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.A1276V	ACH-001669	Leukemia	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.A1276V	ACH-002238	Leukemia	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.A1276V	GR-ST	haematopoietic and lymphoid tissue	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.3056
p.V920F	SIDM00973	Melanoma	GDSC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.0833
p.V920F	WM793B	skin	COSMIC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.0833
p.D919E	SIDM00973	Melanoma	GDSC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.0556
p.D919E	WM793B	skin	COSMIC	PPNY	ITCH	929:932	Mutation rewiring degron network	0.0556
p.H1273Y	SIDM00889	Cervical Carcinoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.6118
p.H1273Y	ACH-001333	Cervical Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.6118
p.H1273Y	C-33-A	cervix	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation altering degron motif	0.6118
p.P4247H	SIDM00965	Small Cell Lung Carcinoma	GDSC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.3056
p.P4247H	ACH-000800	Lung Cancer	CCLE	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.3056
p.P4247H	NCI-H446	lung	COSMIC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.3056
p.H4526L	SIDM00117	Non-Small Cell Lung Carcinoma	GDSC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.25
p.H4526L	ACH-000837	Lung Cancer	CCLE	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.25
p.H4526L	NCI-H322M	lung	COSMIC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.25
p.L4228M	SIDM00844	Burkitt's Lymphoma	GDSC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.0556
p.L4228M	Raji	haematopoietic and lymphoid tissue	COSMIC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.0556
p.D1280Y	SIDM01018	Hodgkin's Lymphoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.D1280Y	ACH-000114	Pancreatic Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.D1280Y	ACH-000815	Lymphoma	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.D1280Y	KM-H2	haematopoietic and lymphoid tissue	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.1944
p.T1277I	SIDM01660	Kidney Carcinoma	GDSC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation blocking phosphorylation signal	0.7222
p.T1277I	ACH-000709	Kidney Cancer	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation blocking phosphorylation signal	0.7222
p.Y4242H	SIDM01451	Pancreatic Carcinoma	GDSC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.834
p.Y4242H	ACH-000933	Pancreatic Cancer	CCLE	NKNIYSDIP	CBL_PTK	4238:4246	Mutation altering degron motif	0.834
p.E1258K	ACH-002238	Leukemia	CCLE	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0833
p.E1258K	GR-ST	haematopoietic and lymphoid tissue	COSMIC	RREPLYHVI	DEG_APCC_DBOX_1	1267:1275	Mutation rewiring degron network	0.0833
p.H4528L	NCI-H322M	lung	COSMIC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.1944
p.L4230M	Raji	haematopoietic and lymphoid tissue	COSMIC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.1111
p.P4349S	HT-1080	soft tissue	COSMIC	ARESLSEVQ	DEG_APCC_DBOX_1	4358:4366	Mutation rewiring degron network	0.0833
p.A4533T	NCI-SNU-1	stomach	COSMIC	PPGY	ITCH	4520:4523	Mutation rewiring degron network	0.0556
p.P4249H	NCI-H446	lung	COSMIC	NKNIYSDIP	CBL_PTK	4238:4246	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

FAT1

UniProt ID: Q14517

Entrez ID: 2195

Protein name: Protocadherin Fat 1 (Cadherin family member 7) (Cadherin-related tumor suppressor homolog) (Protein fat homolog) [Cleaved into: Protocadherin Fat 1, nuclear form]

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for FAT1 in