DegronMD - Q15652(JMJD1C)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E1991K	TCGA-17-Z061	LUAD	TCGA	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.0833
p.T779S	TCGA-22-4596	LUSC	TCGA	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.0833
p.R1308H	TCGA-2W-A8YY	CESC	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.3056
p.R1308H	TCGA-B5-A3FA	UCEC	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.3056
p.D915E	TCGA-2Z-A9J5	KIRP	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.2778
p.P2002L	TCGA-35-4123	LUAD	TCGA	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation altering degron motif	0.7582
p.G1044C	TCGA-39-5040	LUSC	TCGA	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.1111
p.S921C	TCGA-44-6778	LUAD	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1111
p.V1359L	TCGA-44-7670	LUAD	TCGA	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.5654
p.M1302I	TCGA-50-6593	LUAD	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.1389
p.M1302I	TCGA-57-1992	OV	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.1389
p.S1317I	TCGA-86-8358	LUAD	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.2222
p.R1308C	TCGA-A5-A0G2	UCEC	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.3056
p.R1308C	TCGA-AJ-A3OK	UCEC	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.3056
p.R1308C	TCGA-CG-5732	STAD	TCGA	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.3056
p.S1061I	TCGA-A5-A0G2	UCEC	TCGA	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.1944
p.L981R	TCGA-A5-A2K4	UCEC	TCGA	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1389
p.E1045V	TCGA-A6-6781	COAD	TCGA	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.1389
p.E1431K	TCGA-A8-A08H	BRCA	TCGA	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.3056
p.R960I	TCGA-AA-3510	COAD	TCGA	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.0556
p.S1421P	TCGA-AB-2857	LAML	TCGA	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1944
p.G1349R	TCGA-AN-A046	BRCA	TCGA	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.25
p.H1062R	TCGA-AP-A059	UCEC	TCGA	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.1667
p.S900Y	TCGA-AP-A1DV	UCEC	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1111
p.S900Y	TCGA-AX-A06F	UCEC	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1111
p.S1410G	TCGA-BC-4073	LIHC	TCGA	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.25
p.S1054L	TCGA-BS-A0V4	UCEC	TCGA	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation altering degron motif	0.8778
p.T1394A	TCGA-CG-5721	STAD	TCGA	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.0833
p.W904C	TCGA-DK-AA6R	BLCA	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.2222
p.D1404N	TCGA-E6-A8L9	UCEC	TCGA	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation altering degron motif	0.5821
p.E1991D	TCGA-EO-A22R	UCEC	TCGA	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.0833
p.W904R	TCGA-G7-6790	KIRP	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.2222
p.G1412V	TCGA-GM-A2DH	BRCA	TCGA	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.1944
p.L920F	TCGA-H7-A6C4	HNSC	TCGA	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1389
p.R983T	TCGA-KC-A7FA	PRAD	TCGA	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.0833
p.D1362H	TCGA-MT-A67F	HNSC	TCGA	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.2778
p.D1343N	DO48457	BLCA	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.0833
p.E1358Q	DO49759	BLCA	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.6744
p.S1592C	DO44037	BLCA	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation altering degron motif	0.7541
p.S974F	DO219037	BLCA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation altering degron motif	0.9093
p.S1405P	DO225081	BRCA	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation altering degron motif	0.6752
p.S1405P	DO52559	BRCA	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation altering degron motif	0.6752
p.S1593F	DO225037	BRCA	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation rewiring degron network	0.3056
p.S1593F	DO227629	BRCA	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation rewiring degron network	0.3056
p.D1598H	DO2819	BRCA	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation rewiring degron network	0.1667
p.R979C	DO219640	BRCA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.K1348T	DO8730	COAD	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.2222
p.N1395I	DO8722	COAD	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation substituting flanking lysine	0.2222
p.K1344T	DO8264	COAD	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation substituting flanking lysine	0.2222
p.K1344T	DO41799	UCEC	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation substituting flanking lysine	0.2222
p.R1401I	DO8264	COAD	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.2778
p.R1401I	DO41758	UCEC	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.2778
p.F1591L	DO222798	COCA	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation altering degron motif	0.6981
p.F1591L	DO52412	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation altering degron motif	0.6981
p.R979H	DO222884	COCA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.R979H	DO233888	GACA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.V1356A	DO52438	COCA	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.6936
p.T1346S	DO228067	EOPC	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.1667
p.T1322K	DO48211	ESCA	ICGC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.0833
p.S765L	DO223020	ESCA	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.3056
p.S1323N	DO233093	GACA	ICGC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.0556
p.S1064G	DO233207	GACA	ICGC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.1111
p.T1402I	DO14798	HNSC	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.3056
p.K1440N	DO44450	HNSC	ICGC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.0556
p.S1995C	DO228278	LICA	ICGC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.1944
p.T1307K	DO228971	LICA	ICGC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.2778
p.H969N	DO229018	LICA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.3056
p.Q1435K	DO229027	LICA	ICGC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1944
p.P982H	DO229027	LICA	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1111
p.Q1439K	DO229034	LICA	ICGC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.0833
p.A1311E	DO229006	LICA	ICGC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation altering degron motif	0.7701
p.A908E	DO229006	LICA	ICGC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation altering degron motif	0.7701
p.G1410R	DO50970	LICA	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.25
p.A1369T	DO50970	LICA	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.0833
p.K1393T	DO23216	LINC	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.0556
p.D759A	DO231702	LINC	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1389
p.K2001T	DO45241	LIRI	ICGC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation altering degron motif	0.7306
p.Q915K	DO25320	LUAD	ICGC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.2778
p.R979S	DO24692	LUAD	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.R979S	DO37823	SKCM	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.C771F	DO26555	LUSC	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.3056
p.E1408D	DO26433	LUSC	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.3056
p.R961G	DO219161	LUSC	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation blocking ubiquitination signal	0.5278
p.D779N	DO222423	MELA	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.0833
p.D779N	DO37425	SKCM	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.0833
p.S1405F	DO222743	MELA	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation altering degron motif	0.7982
p.D1990N	DO232224	PBCA	ICGC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.0556
p.G1406V	DO229066	PRAD	ICGC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation altering degron motif	0.7532
p.R764T	DO219289	PRAD	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.2778
p.A909V	DO36542	READ	ICGC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation altering degron motif	0.6936
p.S1994R	DO36766	READ	ICGC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.1667
p.I1360S	DO46897	RECA	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.7341
p.A1043E	DO220005	SARC	ICGC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.0833
p.I1588V	DO47809	STAD	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation altering degron motif	0.7076
p.S1301N	DO38288	STAD	ICGC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.1111
p.G1584R	DO223286	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	1588:1592	Mutation rewiring degron network	0.2222
p.L762R	DO43194	UCEC	ICGC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.2222
p.E1358D	DO43186	UCEC	ICGC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.6758
p.S923Y	DO41109	UCEC	ICGC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.0556
p.K1433N	DO43971	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.25
p.S973Y	DO41379	UCEC	ICGC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation altering degron motif	0.712
p.V1433A	SIDM01951	Colorectal Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.25
p.S1429L	SIDM00422	Hodgkin's Lymphoma	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1429L	SIDM00441	Acute Myeloid Leukemia	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1429L	SIDM00920	Breast Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.P901S	SIDM00545	Melanoma	GDSC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1389
p.P901S	ACH-000987	Skin Cancer	CCLE	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1389
p.P901S	Mewo	skin	COSMIC	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1389
p.S2007P	SIDM00082	Melanoma	GDSC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation blocking phosphorylation signal	0.7222
p.S2007P	ACH-001190	Skin Cancer	CCLE	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation blocking phosphorylation signal	0.7222
p.S2007P	SK-MEL-2	skin	COSMIC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation blocking phosphorylation signal	0.7222
p.T1394S	SIDM00741	Small Cell Lung Carcinoma	GDSC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.0833
p.R968W	SIDM00966	Ovarian Carcinoma	GDSC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.R968W	SIDM00217	Colorectal Carcinoma	GDSC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.R968W	ACH-000999	Colon/Colorectal Cancer	CCLE	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.R968W	ACH-002182	Ovarian Cancer	CCLE	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.R968W	OVCA433	ovary	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.R968W	SNU-1040	large intestine	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.Q2006L	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.3056
p.Q2006L	ACH-000824	Esophageal Cancer	CCLE	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.3056
p.Q2006L	KYSE-510	oesophagus	COSMIC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.3056
p.H1365D	SIDM00562	Breast Carcinoma	GDSC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.1944
p.H1365D	ACH-002163	Breast Cancer	CCLE	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.1944
p.H1365D	MRK-nu-1	breast	COSMIC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.1944
p.S1430L	SIDM00596	Endometrial Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1430L	ACH-000941	Endometrial/Uterine Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1430L	ACH-000954	Endometrial/Uterine Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1430L	ACH-001517	Endometrial/Uterine Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.S1430L	HEC-1	endometrium	COSMIC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.7667
p.K1060E	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.K1060E	SIDM00252	Biliary Tract Carcinoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.K1060E	SIDM00907	Burkitt's Lymphoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.K1060E	SIDM01210	Glioblastoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.K1060E	SIDM00970	Bladder Carcinoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.K1060E	SIDM00503	Gastric Carcinoma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation substituting flanking lysine	0.3333
p.G1413D	SIDM00883	Non-Cancerous	GDSC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.1667
p.G1413D	ACH-002382	Non-Cancerous	CCLE	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.1667
p.L758S	SIDM00140	Melanoma	GDSC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1111
p.L758S	ACH-000968	Skin Cancer	CCLE	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1111
p.L758S	COLO-792	skin	COSMIC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1111
p.S1429P	SIDM00738	Non-Small Cell Lung Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6752
p.S1429P	ACH-000282	Lung Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6752
p.S1429P	NCI-H1755	lung	COSMIC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6752
p.D1993V	SIDM00604	Oral Cavity Carcinoma	GDSC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.1389
p.D1993V	ACH-001542	Head and Neck Cancer	CCLE	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.1389
p.D1993V	KON	upper aerodigestive tract	COSMIC	LTPPES	DEG_SCF_FBW7_1	2000:2005	Mutation rewiring degron network	0.1389
p.E965D	SIDM00628	Breast Carcinoma	GDSC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.1944
p.Q1066R	SIDM01575	Plasma Cell Myeloma	GDSC	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.0556
p.Q1066R	ACH-000426	Myeloma	CCLE	VASSS	DEG_SPOP_SBC_1	1052:1056	Mutation rewiring degron network	0.0556
p.G1352R	ACH-000923	Lymphoma	CCLE	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.6457
p.S902C	ACH-000982	Colon/Colorectal Cancer	CCLE	PTPVTS	DEG_SCF_FBW7_1	908:913	Mutation rewiring degron network	0.1667
p.L774F	ACH-001802	Liposarcoma	CCLE	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.2222
p.G976S	KYSE-520	oesophagus	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.G976S	JHH-2	liver	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.G976S	NY	bone	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.G976S	HuCCT1	biliary tract	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.G976S	OSC-19	upper aerodigestive tract	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.G976S	AN3-CA	endometrium	COSMIC	VASTS	DEG_SPOP_SBC_1	970:974	Mutation rewiring degron network	0.2778
p.V1393L	NCI-H747	large intestine	COSMIC	ADTTS	DEG_SPOP_SBC_1	1403:1407	Mutation rewiring degron network	0.0556
p.L776I	Ca-Ski	cervix	COSMIC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1667
p.K773E	HCT-15	large intestine	COSMIC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.25
p.I1421T	PANC-04-03	pancreas	COSMIC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1944
p.I1421T	OCI-AML3	haematopoietic and lymphoid tissue	COSMIC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation rewiring degron network	0.1944
p.K1430N	HCT-15	large intestine	COSMIC	ASTSS	DEG_SPOP_SBC_1	1426:1430	Mutation altering degron motif	0.6918
p.S1315R	SNU-475	liver	COSMIC	PSSST	DEG_SPOP_SBC_1	1309:1313	Mutation rewiring degron network	0.2778
p.H1365L	SW1710	urinary tract	COSMIC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.1944
p.V1351L	KMH-2	thyroid	COSMIC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.3056
p.H759R	NCI-H2291	lung	COSMIC	AGSSS	DEG_SPOP_SBC_1	766:770	Mutation rewiring degron network	0.1389
p.S1360R	SCC-9	upper aerodigestive tract	COSMIC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation altering degron motif	0.7427
p.N1349H	HT-115	large intestine	COSMIC	GRIILPNVN	DEG_APCC_DBOX_1	1352:1360	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

JMJD1C

UniProt ID: Q15652

Entrez ID: 221037

Protein name: Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C) (Thyroid receptor-interacting protein 8) (TR-interacting protein 8) (TRIP-8)

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for JMJD1C in