DegronMD - Q5VT52(RPRD2)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K494E	TCGA-06-5416	GBM	TCGA	PATTT	DEG_SPOP_SBC_1	498:502	Mutation substituting flanking lysine	0.3333
p.S599Y	TCGA-06-5416	GBM	TCGA	PNSST	DEG_SPOP_SBC_1	594:598	Mutation rewiring degron network	0.3056
p.S599Y	TCGA-06-5416	GBM	TCGA	VSSTS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.2778
p.P496H	TCGA-2Z-A9J6	KIRP	TCGA	PATTT	DEG_SPOP_SBC_1	498:502	Mutation rewiring degron network	0.2778
p.T148S	TCGA-3C-AALI	BRCA	TCGA	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1389
p.T148S	DO219589	BRCA	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1389
p.S491G	TCGA-67-3771	LUAD	TCGA	PATTT	DEG_SPOP_SBC_1	498:502	Mutation blocking phosphorylation signal	0.5833
p.P1448S	TCGA-78-8648	LUAD	TCGA	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0556
p.P163L	TCGA-A5-A0G1	UCEC	TCGA	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.2222
p.P163L	DO42472	UCEC	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.2222
p.S826Y	TCGA-AG-A002	READ	TCGA	DYRDFEYSGPP	CBL_PTK	832:842	Mutation blocking phosphorylation signal	0.6111
p.S826Y	TCGA-AG-A002	READ	TCGA	DYR	CBL_MET	832:834	Mutation blocking phosphorylation signal	0.6111
p.L753F	TCGA-AP-A1DP	UCEC	TCGA	PTSSS	DEG_SPOP_SBC_1	742:746	Mutation rewiring degron network	0.1389
p.L753F	TCGA-AP-A1DP	UCEC	TCGA	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.1667
p.T713A	TCGA-B5-A5OC	UCEC	TCGA	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation altering degron motif	0.6028
p.T404I	TCGA-BP-4963	KIRC	TCGA	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.25
p.P587T	TCGA-CA-6717	COAD	TCGA	PNSST	DEG_SPOP_SBC_1	594:598	Mutation rewiring degron network	0.1389
p.P842S	TCGA-CK-4951	COAD	TCGA	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.6752
p.P1448L	TCGA-CM-6171	COAD	TCGA	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0556
p.P1448L	SIDM00545	Melanoma	GDSC	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0556
p.P1448L	ACH-000987	Skin Cancer	CCLE	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0556
p.P1448L	Mewo	skin	COSMIC	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0556
p.Y592C	TCGA-CV-A6K1	HNSC	TCGA	PNSST	DEG_SPOP_SBC_1	594:598	Mutation blocking phosphorylation signal	0.7222
p.Y592C	TCGA-CV-A6K1	HNSC	TCGA	VSSTS	DEG_SPOP_SBC_1	601:605	Mutation blocking phosphorylation signal	0.5278
p.I510V	TCGA-DD-AAEA	LIHC	TCGA	PATTT	DEG_SPOP_SBC_1	498:502	Mutation rewiring degron network	0.1111
p.D824E	TCGA-DD-AAVV	LIHC	TCGA	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.1111
p.D824E	TCGA-DD-AAVV	LIHC	TCGA	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.1111
p.P322S	TCGA-DU-6407	LGG	TCGA	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.6752
p.P594H	TCGA-EE-A3AA	SKCM	TCGA	PNSST	DEG_SPOP_SBC_1	594:598	Mutation altering degron motif	0.7694
p.N164D	TCGA-EO-A22R	UCEC	TCGA	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1944
p.N164D	DO42713	UCEC	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1944
p.S839A	TCGA-EO-A22R	UCEC	TCGA	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.7588
p.S323F	TCGA-FR-A7U9	SKCM	TCGA	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.7982
p.S323F	SIDM00007	Other Solid Cancers	GDSC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.7982
p.S323F	ACH-001550	Skin Cancer	CCLE	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.7982
p.S323F	MCC13	skin	COSMIC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.7982
p.P1458S	TCGA-FW-A3TU	SKCM	TCGA	PPRY	ITCH	1458:1461	Mutation altering degron motif	0.6752
p.P324S	TCGA-GN-A267	SKCM	TCGA	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.6752
p.Q709K	TCGA-HE-7129	KIRP	TCGA	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.25
p.K391E	TCGA-KN-8422	KICH	TCGA	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation substituting flanking lysine	0.2778
p.K588R	TCGA-N5-A4RD	UCS	TCGA	PNSST	DEG_SPOP_SBC_1	594:598	Mutation substituting flanking lysine	0.2778
p.K755N	TCGA-UY-A78O	BLCA	TCGA	PTSSS	DEG_SPOP_SBC_1	742:746	Mutation substituting flanking lysine	0.1944
p.K755N	TCGA-UY-A78O	BLCA	TCGA	PGSST	DEG_SPOP_SBC_1	759:763	Mutation substituting flanking lysine	0.3333
p.F1450V	TCGA-VQ-A8DL	STAD	TCGA	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.1111
p.Y822C	TCGA-VQ-AA6G	STAD	TCGA	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.0556
p.Y822C	TCGA-VQ-AA6G	STAD	TCGA	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.0556
p.D721N	TCGA-XF-A8HD	BLCA	TCGA	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.1944
p.F1457V	TCGA-XU-A92T	THYM	TCGA	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.3056
p.L403V	DO224847	BRCA	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.2778
p.L403V	DO227473	BRCA	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.2778
p.E328K	DO51612	CESC	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.2222
p.E328K	SW954	vulva	COSMIC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.2222
p.E842K	DO230334	COCA	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.7022
p.E334K	DO222441	ESCA	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.0556
p.A2V	DO233089	GACA	ICGC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation blocking phosphorylation signal	0.5
p.T595A	DO233663	GACA	ICGC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation altering degron motif	0.7139
p.L756I	DO233791	GACA	ICGC	PTSSS	DEG_SPOP_SBC_1	742:746	Mutation rewiring degron network	0.0556
p.L756I	DO233791	GACA	ICGC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.25
p.E493D	DO14694	HNSC	ICGC	PATTT	DEG_SPOP_SBC_1	498:502	Mutation rewiring degron network	0.1944
p.E755A	DO44501	KIRP	ICGC	PTSSS	DEG_SPOP_SBC_1	742:746	Mutation substituting flanking lysine	0.1944
p.E755A	DO44501	KIRP	ICGC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation substituting flanking lysine	0.3333
p.L832M	DO22237	LGG	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.711
p.L832M	DO22237	LGG	ICGC	DYR	CBL_MET	832:834	Mutation altering degron motif	0.711
p.G512V	DO228330	LICA	ICGC	PATTT	DEG_SPOP_SBC_1	498:502	Mutation blocking phosphorylation signal	0.5
p.Q313H	DO228948	LICA	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.2778
p.G769C	DO228971	LICA	ICGC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation blocking phosphorylation signal	0.6111
p.E309D	DO229022	LICA	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.1667
p.K836N	DO229036	LICA	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.6918
p.G317S	DO229043	LICA	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.6993
p.K157N	DO229050	LICA	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation altering degron motif	0.6918
p.S10G	DO23498	LINC	ICGC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2778
p.N408K	DO45299	LIRI	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.1389
p.E24G	DO45295	LIRI	ICGC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.1111
p.P404S	DO224563	LUSC	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.25
p.R703L	DO26456	LUSC	ICGC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0833
p.S322L	DO228414	MALY	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation altering degron motif	0.7667
p.S725F	DO220903	MELA	ICGC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0833
p.P845S	DO222395	MELA	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.25
p.P305S	DO222420	MELA	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation substituting flanking lysine	0.1667
p.I495V	DO32143	OV	ICGC	PATTT	DEG_SPOP_SBC_1	498:502	Mutation blocking phosphorylation signal	0.6944
p.G767D	DO30980	OV	ICGC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation blocking phosphorylation signal	0.6667
p.S19L	DO52124	PAEN	ICGC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.25
p.L167I	DO37523	SKCM	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1111
p.P311L	DO37782	SKCM	ICGC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.2222
p.R703Q	DO47739	STAD	ICGC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0833
p.L847M	DO42280	UCEC	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.1944
p.A387V	DO42280	UCEC	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.0556
p.S410Y	DO43186	UCEC	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation rewiring degron network	0.0833
p.S147Y	DO41799	UCEC	ICGC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.1111
p.K829N	DO42568	UCEC	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.25
p.K829N	DO42568	UCEC	ICGC	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.25
p.T400N	DO41235	UCEC	ICGC	AVSTS	DEG_SPOP_SBC_1	397:401	Mutation altering degron motif	0.7055
p.S830F	DO41361	UCEC	ICGC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.2778
p.S830F	DO41361	UCEC	ICGC	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.2778
p.S9N	SIDM01016	T-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.25
p.S9N	SIDM01263	T-Lymphoblastic Leukemia	GDSC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.25
p.S9N	ACH-000995	Leukemia	CCLE	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.25
p.S9N	Jurkat	haematopoietic and lymphoid tissue	COSMIC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.25
p.A20T	SIDM00373	Endometrial Carcinoma	GDSC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.A20T	ACH-000974	Endometrial/Uterine Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.A20T	ACH-002026	Endometrial/Uterine Cancer	CCLE	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.A20T	SNG-M	endometrium	COSMIC	ASSSS	DEG_SPOP_SBC_1	12:16	Mutation rewiring degron network	0.2222
p.P594L	SIDM00967	Ovarian Carcinoma	GDSC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation altering degron motif	0.7582
p.P594L	ACH-002181	Ovarian Cancer	CCLE	PNSST	DEG_SPOP_SBC_1	594:598	Mutation altering degron motif	0.7582
p.P594L	OVCA420	ovary	COSMIC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation altering degron motif	0.7582
p.P772S	SIDM00427	Ewing's Sarcoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM00671	T-Cell Non-Hodgkin's Lymphoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01130	Squamous Cell Lung Carcinoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01060	Melanoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM00516	Melanoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM00621	Ewing's Sarcoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM00677	Colorectal Carcinoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01128	Small Cell Lung Carcinoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM00205	Ewing's Sarcoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01879	Non-Cancerous	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01667	B-Cell Non-Hodgkin's Lymphoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.P772S	SIDM01761	Rhabdomyosarcoma	GDSC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.E702Q	SIDM00633	Breast Carcinoma	GDSC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.E702Q	ACH-000759	Breast Cancer	CCLE	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.E702Q	MDA-MB-175-VII	breast	COSMIC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.G722E	SIDM00633	Breast Carcinoma	GDSC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.1667
p.G722E	ACH-000759	Breast Cancer	CCLE	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.1667
p.G722E	MDA-MB-175-VII	breast	COSMIC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.1667
p.E831G	SIDM01045	Endometrial Carcinoma	GDSC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.3056
p.E831G	SIDM01045	Endometrial Carcinoma	GDSC	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.3056
p.E831G	ACH-000978	Endometrial/Uterine Cancer	CCLE	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.3056
p.E831G	ACH-000978	Endometrial/Uterine Cancer	CCLE	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.3056
p.E831G	EN	endometrium	COSMIC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.3056
p.E831G	EN	endometrium	COSMIC	DYR	CBL_MET	832:834	Mutation rewiring degron network	0.3056
p.R710H	SIDM00511	Small Cell Lung Carcinoma	GDSC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.2778
p.E702K	SIDM00252	Biliary Tract Carcinoma	GDSC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.E702K	ACH-001861	Gallbladder Cancer	CCLE	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.E702K	TGBC1TKB	biliary tract	COSMIC	PTSTS	DEG_SPOP_SBC_1	712:716	Mutation rewiring degron network	0.0556
p.M846V	SIDM00276	Biliary Tract Carcinoma	GDSC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.2222
p.M846V	SIDM01210	Glioblastoma	GDSC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation rewiring degron network	0.2222
p.F1449L	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0833
p.F1449L	ACH-000886	Lung Cancer	CCLE	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0833
p.F1449L	NCI-H2009	lung	COSMIC	PPRY	ITCH	1458:1461	Mutation rewiring degron network	0.0833
p.P329L	SIDM00140	Melanoma	GDSC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.1944
p.P329L	ACH-000968	Skin Cancer	CCLE	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.1944
p.P329L	COLO-792	skin	COSMIC	DPEESPVPSP	DEG_COP1_1	315:324	Mutation rewiring degron network	0.1944
p.P772R	ACH-000122	Leukemia	CCLE	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.0833
p.S758G	ACH-001664	Gastric Cancer	CCLE	PGSST	DEG_SPOP_SBC_1	759:763	Mutation blocking phosphorylation signal	0.75
p.S593N	TOV-21G	ovary	COSMIC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation blocking phosphorylation signal	0.75
p.S593N	TOV-21G	ovary	COSMIC	VSSTS	DEG_SPOP_SBC_1	601:605	Mutation blocking phosphorylation signal	0.5556
p.K151T	SK-MEL-3	skin	COSMIC	LKENL	DEG_APCC_KENBOX_2	155:159	Mutation rewiring degron network	0.2222
p.S600F	KYSE-270	oesophagus	COSMIC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation rewiring degron network	0.2778
p.S600F	KYSE-270	oesophagus	COSMIC	VSSTS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.3056
p.T606A	CAL-29	urinary tract	COSMIC	PNSST	DEG_SPOP_SBC_1	594:598	Mutation rewiring degron network	0.1111
p.T606A	CAL-29	urinary tract	COSMIC	VSSTS	DEG_SPOP_SBC_1	601:605	Mutation rewiring degron network	0.3056
p.S835N	KYSE-270	oesophagus	COSMIC	DYRDFEYSGPP	CBL_PTK	832:842	Mutation altering degron motif	0.7069
p.R754L	SK-MES-1	lung	COSMIC	PTSSS	DEG_SPOP_SBC_1	742:746	Mutation rewiring degron network	0.1111
p.R754L	SK-MES-1	lung	COSMIC	PGSST	DEG_SPOP_SBC_1	759:763	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

RPRD2

UniProt ID: Q5VT52

Entrez ID: 23248

Protein name: Regulation of nuclear pre-mRNA domain-containing protein 2

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for RPRD2 in