p.G3492C | TCGA-18-3411 | LUSC | TCGA | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.25 |
p.R4827S | TCGA-18-5595 | LUSC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.0833 |
p.P4829L | TCGA-21-1079 | LUSC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1389 |
p.T1312S | TCGA-44-3918 | LUAD | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.T1312S | DO23732 | LUAD | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.D4831H | TCGA-46-3769 | LUSC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1944 |
p.S1314C | TCGA-66-2785 | LUSC | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.25 |
p.S1314C | DO26520 | LUSC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.25 |
p.D3484Y | TCGA-91-A4BC | LUAD | TCGA | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation altering degron motif | 0.7325 |
p.D2078A | TCGA-A5-A1OF | UCEC | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.7793 |
p.L3V | TCGA-AA-3949 | COAD | TCGA | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | TCGA-BR-6453 | STAD | TCGA | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | TCGA-DM-A28F | COAD | TCGA | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | DO7798 | COAD | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | DO9828 | COAD | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | DO227995 | COCA | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | DO234463 | ESAD | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.L3V | DO38543 | STAD | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.6765 |
p.T2063K | TCGA-AA-3976 | COAD | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7306 |
p.P2077T | TCGA-AA-A01V | COAD | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.0556 |
p.P2077T | TCGA-AA-A01V | COAD | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.3056 |
p.P2077R | TCGA-AA-A01V | COAD | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.0556 |
p.P2077R | TCGA-AA-A01V | COAD | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.3056 |
p.A4830V | TCGA-AC-A8OQ | BRCA | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1667 |
p.A4830V | SIDM00217 | Colorectal Carcinoma | GDSC | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1667 |
p.A4830V | ACH-000999 | Colon/Colorectal Cancer | CCLE | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1667 |
p.A4830V | SNU-1040 | large intestine | COSMIC | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1667 |
p.Y2058N | TCGA-AH-6897 | READ | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.2778 |
p.L1320F | TCGA-AJ-A3EL | UCEC | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6981 |
p.L1320F | DO41542 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6981 |
p.S4847F | TCGA-AX-A2HD | UCEC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1389 |
p.T4570I | TCGA-AY-6386 | COAD | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.25 |
p.S3495F | TCGA-B5-A1MX | UCEC | TCGA | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.1667 |
p.G4577E | TCGA-BF-AAOX | SKCM | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.0556 |
p.A3482D | TCGA-BR-8680 | STAD | TCGA | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.I2085T | TCGA-BS-A0UF | UCEC | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.2778 |
p.F4556C | TCGA-CA-6717 | COAD | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.1667 |
p.S4844P | TCGA-CA-6717 | COAD | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.G4832C | TCGA-CN-A63U | HNSC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.G4832C | TCGA-D3-A2J6 | SKCM | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.R1329I | TCGA-D1-A103 | UCEC | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1667 |
p.R1329I | DO42312 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1667 |
p.P4829Q | TCGA-D3-A3C8 | SKCM | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1389 |
p.P2060S | TCGA-D3-A8GI | SKCM | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.6752 |
p.D4560E | TCGA-D5-6530 | COAD | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.2778 |
p.P4564S | TCGA-EB-A41A | SKCM | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation altering degron motif | 0.6752 |
p.P4559L | TCGA-EB-A6QZ | SKCM | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.25 |
p.A4830S | TCGA-EI-6512 | READ | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1667 |
p.E2061D | TCGA-EO-A3B0 | UCEC | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.5647 |
p.S4839C | TCGA-FD-A3B8 | BLCA | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation altering degron motif | 0.7541 |
p.R1329K | TCGA-FI-A2D5 | UCEC | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1667 |
p.R1329K | DO41331 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1667 |
p.T2088I | TCGA-FJ-A3ZE | BLCA | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1944 |
p.S4839F | TCGA-FS-A1ZF | SKCM | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation altering degron motif | 0.7982 |
p.H4845N | TCGA-FS-A1ZJ | SKCM | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1944 |
p.H4845N | TCGA-GN-A26C | SKCM | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.1944 |
p.S3485L | TCGA-FW-A3R5 | SKCM | TCGA | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation altering degron motif | 0.7667 |
p.D1323E | TCGA-G2-A2EF | BLCA | TCGA | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.5647 |
p.D1323E | DO726 | BLCA | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.5647 |
p.P2092L | TCGA-GN-A26A | SKCM | TCGA | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.0833 |
p.S4844C | TCGA-MZ-A7D7 | HNSC | TCGA | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.D4557N | TCGA-OD-A75X | SKCM | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.1944 |
p.P4564L | TCGA-YD-A89C | SKCM | TCGA | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation altering degron motif | 0.6471 |
p.P4564L | ACH-001566 | Skin Cancer | CCLE | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation altering degron motif | 0.6471 |
p.S2053F | TCGA-ZF-AA4V | BLCA | TCGA | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1389 |
p.L2060P | DO222652 | BTCA | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7582 |
p.T4P | DO223732 | CESC | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.8142 |
p.R2066Q | DO52717 | CLLE | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7329 |
p.R2066Q | DO9772 | COAD | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7329 |
p.A2063V | DO51734 | COAD | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.6936 |
p.R2090Q | DO222765 | COCA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.L2060R | DO222709 | COCA | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.8428 |
p.L2060R | DO51763 | STAD | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.8428 |
p.T1319K | DO228092 | EOPC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6195 |
p.L24F | DO234218 | ESAD | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.1111 |
p.V2077I | DO223058 | ESCA | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.0556 |
p.V2077I | DO223058 | ESCA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.3056 |
p.V2077I | DO42057 | UCEC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.0556 |
p.V2077I | DO42057 | UCEC | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.3056 |
p.R2090W | DO233041 | GACA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.R2090W | DO52034 | HNSC | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.R2090W | DO48729 | LGG | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.R2090W | DO33368 | PACA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.R2090W | EW-16 | bone | COSMIC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.R2090W | LAMA-84 | haematopoietic and lymphoid tissue | COSMIC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1389 |
p.G1331A | DO233262 | GACA | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1111 |
p.R11L | DO233707 | GACA | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7316 |
p.D1310Y | DO13863 | GBM | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1389 |
p.D1310Y | DO219146 | LUSC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1389 |
p.D1310Y | DO41211 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1389 |
p.G1312E | DO11854 | GBM | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.F1320L | DO219026 | HNSC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6981 |
p.F1320L | DO41524 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6981 |
p.A18S | DO228971 | LICA | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.2778 |
p.V2072L | DO229027 | LICA | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1944 |
p.V2072L | DO229027 | LICA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.1667 |
p.G2093R | DO26240 | LUAD | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.0556 |
p.G1312V | DO26469 | LUSC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.F2081S | DO219139 | LUSC | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.7982 |
p.T4M | DO27791 | MALY | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.8534 |
p.P15S | DO220902 | MELA | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.5641 |
p.E2053K | DO222504 | MELA | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1389 |
p.E2086K | DO222775 | MELA | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.25 |
p.E2086K | DO47665 | SKCM | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.25 |
p.E2086K | DO47646 | SKCM | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.25 |
p.M1328I | DO27879 | ORCA | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.P5T | DO27901 | ORCA | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7031 |
p.H17R | DO46518 | OV | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.3056 |
p.A19G | DO28102 | OV | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.25 |
p.A2062S | DO220011 | SARC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7588 |
p.V2I | DO37418 | SKCM | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.3056 |
p.V5I | DO37406 | SKCM | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7076 |
p.G1312R | DO48766 | SKCM | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.P2074S | DO47419 | SKCM | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1389 |
p.P2074S | DO47419 | SKCM | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.2222 |
p.P2074S | DO219487 | SKCM | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1389 |
p.P2074S | DO219487 | SKCM | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.2222 |
p.P2074S | HCC2998 | large intestine | COSMIC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1389 |
p.P2074S | HCC2998 | large intestine | COSMIC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.2222 |
p.S1315P | DO47769 | STAD | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.2778 |
p.A2051T | DO43306 | UCEC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.0833 |
p.T2058M | DO43186 | UCEC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.2778 |
p.R2057I | DO43154 | UCEC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.25 |
p.D1307Y | DO41572 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.0556 |
p.H2068N | DO43923 | UCEC | ICGC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.3056 |
p.H2068N | DO43923 | UCEC | ICGC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation rewiring degron network | 0.0556 |
p.K1309E | DO42568 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1111 |
p.E1318D | DO42568 | UCEC | ICGC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation altering degron motif | 0.6758 |
p.F22V | DO41331 | UCEC | ICGC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.1667 |
p.T3491K | SIDM00338 | Acute Myeloid Leukemia | GDSC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.T3491K | ACH-000439 | Leukemia | CCLE | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.T3491K | ME-1 | haematopoietic and lymphoid tissue | COSMIC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.G1331C | SIDM01119 | Other Solid Cancers | GDSC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1111 |
p.G1331C | ACH-000775 | Lung Cancer | CCLE | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1111 |
p.G1331C | NCI-H727 | lung | COSMIC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1111 |
p.P3474L | SIDM00545 | Melanoma | GDSC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.0556 |
p.P3474L | ACH-000987 | Skin Cancer | CCLE | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.0556 |
p.P3474L | Mewo | skin | COSMIC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.0556 |
p.P2064H | SIDM00113 | Kidney Carcinoma | GDSC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7694 |
p.P2064H | ACH-001208 | Kidney Cancer | CCLE | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7694 |
p.P2064H | TK10 | kidney | COSMIC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation altering degron motif | 0.7694 |
p.A4T | SIDM00506 | Small Cell Lung Carcinoma | GDSC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7139 |
p.A4T | ACH-000508 | Lung Cancer | CCLE | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7139 |
p.A4T | COR-L88 | lung | COSMIC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation altering degron motif | 0.7139 |
p.E4552K | SIDM00860 | Head and Neck Carcinoma | GDSC | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.0556 |
p.E4552K | ACH-000846 | Head and Neck Cancer | CCLE | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.0556 |
p.E4552K | FADU | upper aerodigestive tract | COSMIC | IPPYGD | LIG_APCC_ABBA_1 | 4562:4567 | Mutation rewiring degron network | 0.0556 |
p.L3481F | SIDM00230 | Small Cell Lung Carcinoma | GDSC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.25 |
p.L3481F | ACH-002145 | Lung Cancer | CCLE | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.25 |
p.L3481F | IST-SL2 | lung | COSMIC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.25 |
p.M1328T | SIDM00247 | Gastric Carcinoma | GDSC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.M1328T | SIDM01019 | Acute Myeloid Leukemia | GDSC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.M1328T | ACH-000356 | Gastric Cancer | CCLE | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.M1328T | ACH-002258 | Leukemia | CCLE | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.M1328T | MKN45 | stomach | COSMIC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.M1328T | KMOE-2 | haematopoietic and lymphoid tissue | COSMIC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.1944 |
p.R26Q | SIDM00118 | Colorectal Carcinoma | GDSC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.0556 |
p.R26Q | ACH-001081 | Colon/Colorectal Cancer | CCLE | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.0556 |
p.R26Q | HCC2998 | large intestine | COSMIC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.0556 |
p.G2080S | SIDM01059 | Melanoma | GDSC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.6993 |
p.G2080S | ACH-000915 | Skin Cancer | CCLE | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.6993 |
p.G2080S | IPC-298 | skin | COSMIC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.6993 |
p.S4844Y | SIDM00257 | Neuroblastoma | GDSC | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.S4844Y | ACH-002280 | Neuroblastoma | CCLE | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.S4844Y | NB13 | autonomic ganglia | COSMIC | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2222 |
p.A3482T | SIDM01608 | Endometrial Carcinoma | GDSC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.A3482T | ACH-000990 | Endometrial/Uterine Cancer | CCLE | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2778 |
p.L2052I | SIDM01611 | Endometrial Carcinoma | GDSC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1111 |
p.L2052I | ACH-000996 | Endometrial/Uterine Cancer | CCLE | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation rewiring degron network | 0.1111 |
p.V3480F | SIDM01605 | Non-Small Cell Lung Carcinoma | GDSC | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2222 |
p.V3480F | ACH-000891 | Lung Cancer | CCLE | DSGTPS | DEG_SCF_TRCP1_1 | 3484:3489 | Mutation rewiring degron network | 0.2222 |
p.S4842C | SIDM01378 | Ovarian Carcinoma | GDSC | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2778 |
p.S4842C | ACH-000646 | Ovarian Cancer | CCLE | PESSS | DEG_SPOP_SBC_1 | 4836:4840 | Mutation rewiring degron network | 0.2778 |
p.K2071R | SIDM01561 | Melanoma | GDSC | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation substituting flanking lysine | 0.3333 |
p.K2071R | SIDM01561 | Melanoma | GDSC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation substituting flanking lysine | 0.25 |
p.K2071R | ACH-000799 | Skin Cancer | CCLE | PENTPIDT | DEG_SCF_FBW7_1 | 2060:2067 | Mutation substituting flanking lysine | 0.3333 |
p.K2071R | ACH-000799 | Skin Cancer | CCLE | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation substituting flanking lysine | 0.25 |
p.L19I | SIDM01588 | Endometrial Carcinoma | GDSC | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.25 |
p.L19I | ACH-000993 | Endometrial/Uterine Cancer | CCLE | LAPDRATGRPWLPL | DEG_ODPH_VHL_1 | 3:16 | Mutation rewiring degron network | 0.25 |
p.D1307H | HT-1376 | urinary tract | COSMIC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.0556 |
p.F2080L | GP5d | large intestine | COSMIC | DSGPNS | DEG_SCF_TRCP1_1 | 2078:2083 | Mutation altering degron motif | 0.6981 |
p.D1308Y | HT-1376 | urinary tract | COSMIC | KSTLFVD | LIG_APCC_ABBAyCdc20_2 | 1317:1323 | Mutation rewiring degron network | 0.0833 |