DegronMD - Q92545(TMEM131)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.R1617L	TCGA-17-Z049	LUAD	TCGA	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.R1617L	TCGA-FS-A1ZR	SKCM	TCGA	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.R1617L	DO37651	SKCM	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.R957K	TCGA-77-8148	LUSC	TCGA	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.7237
p.R957K	DO26458	LUSC	ICGC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.7237
p.D1850V	TCGA-86-8073	LUAD	TCGA	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.2222
p.D1850V	DO23624	LUAD	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.2222
p.S1574C	TCGA-86-8279	LUAD	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation altering degron motif	0.7541
p.S1574C	DO24140	LUAD	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation altering degron motif	0.7541
p.A1849S	TCGA-92-7341	LUSC	TCGA	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.25
p.A1849S	DO26677	LUSC	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.25
p.N1638H	TCGA-A5-A2K5	UCEC	TCGA	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.0556
p.N1638H	DO41379	UCEC	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.0556
p.R1617Q	TCGA-AB-2807	LAML	TCGA	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.R1617Q	DO233168	GACA	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.R1617Q	DO21589	LAML	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.D964Y	TCGA-AP-A059	UCEC	TCGA	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.6214
p.D964Y	DO41361	UCEC	ICGC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.6214
p.V1710I	TCGA-BR-7851	STAD	TCGA	PDFTPLNS	DEG_SCF_FBW7_1	1716:1723	Mutation rewiring degron network	0.1667
p.V1710I	DO38711	STAD	ICGC	PDFTPLNS	DEG_SCF_FBW7_1	1716:1723	Mutation rewiring degron network	0.1667
p.G1797S	TCGA-BS-A0TC	UCEC	TCGA	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.G1797S	DO42400	UCEC	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.G1797S	SIDM00143	Small Cell Lung Carcinoma	GDSC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.G1797S	ACH-000803	Lung Cancer	CCLE	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.G1797S	COLO-668	lung	COSMIC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.S1575C	TCGA-D1-A1NS	UCEC	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation altering degron motif	0.7541
p.S1575C	DO42193	UCEC	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation altering degron motif	0.7541
p.S1566F	TCGA-D3-A8GC	SKCM	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1667
p.S1566F	DO50281	SKCM	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1667
p.S1837F	TCGA-D3-A8GM	SKCM	TCGA	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.S1837F	DO50288	SKCM	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.S1837F	SIDM00118	Colorectal Carcinoma	GDSC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.S1837F	ACH-001081	Colon/Colorectal Cancer	CCLE	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.S1837F	HCC2998	large intestine	COSMIC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.E1563D	TCGA-DD-A4NV	LIHC	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.0833
p.E1563D	DO44876	LIHC	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.0833
p.S1800P	TCGA-DI-A1BU	UCEC	TCGA	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.25
p.S1800P	DO42023	UCEC	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.25
p.T1490N	TCGA-DU-6392	LGG	TCGA	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation altering degron motif	0.8166
p.T1490N	DO22237	LGG	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation altering degron motif	0.8166
p.A1726T	TCGA-EA-A3HS	CESC	TCGA	PDFTPLNS	DEG_SCF_FBW7_1	1716:1723	Mutation rewiring degron network	0.25
p.A1726T	DO6260	CESC	ICGC	PDFTPLNS	DEG_SCF_FBW7_1	1716:1723	Mutation rewiring degron network	0.25
p.W1564L	TCGA-EB-A299	SKCM	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1111
p.W1564L	DO37794	SKCM	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1111
p.V1567D	TCGA-EE-A3JH	SKCM	TCGA	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1944
p.V1567D	DO47595	SKCM	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1944
p.T974P	TCGA-EO-A3B0	UCEC	TCGA	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation rewiring degron network	0.0556
p.T974P	DO219773	UCEC	ICGC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation rewiring degron network	0.0556
p.G1830D	TCGA-FI-A2D0	UCEC	TCGA	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.1944
p.G1830D	DO43891	UCEC	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.1944
p.S1503N	TCGA-FW-A3TU	SKCM	TCGA	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.0833
p.S1503N	DO37441	SKCM	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.0833
p.P1374T	TCGA-G7-6797	KIRP	TCGA	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.25
p.P1374T	DO20917	KIRP	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.25
p.A1816V	TCGA-IB-7651	PAAD	TCGA	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816V	TCGA-IB-7651	PAAD	TCGA	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.A1816V	DO46657	PAAD	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816V	DO46657	PAAD	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.S1806R	TCGA-IB-7651	PAAD	TCGA	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation altering degron motif	0.7427
p.S1806R	DO46657	PAAD	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation altering degron motif	0.7427
p.P1477S	TCGA-W3-AA1R	SKCM	TCGA	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.0556
p.P1477S	DO51275	SKCM	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.0556
p.E23Q	DO5507	BRCA	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.25
p.R26H	DO8240	COAD	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1667
p.R26H	DO13462	GBM	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1667
p.R26H	DO41871	UCEC	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.1667
p.F1614V	DO230346	COCA	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.0556
p.A1816T	DO230342	COCA	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816T	DO230342	COCA	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.A1816T	SIDM00451	T-Lymphoblastic Leukemia	GDSC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816T	SIDM00451	T-Lymphoblastic Leukemia	GDSC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.A1816T	ACH-000937	Leukemia	CCLE	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816T	ACH-000937	Leukemia	CCLE	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.A1816T	PF-382	haematopoietic and lymphoid tissue	COSMIC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.2778
p.A1816T	PF-382	haematopoietic and lymphoid tissue	COSMIC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0833
p.T1825M	DO227646	COCA	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation altering degron motif	0.7423
p.D1359N	DO229010	COCA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	DO229013	COCA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	DO229016	COCA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	DO229003	COCA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	DO230937	LUSC	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	DO231149	LUSC	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00425	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00321	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00194	Colorectal Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00557	Neuroblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00993	Plasma Cell Myeloma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00615	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00572	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00075	Non-Cancerous	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00064	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00352	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00535	Chondrosarcoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00600	Thyroid Gland Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00551	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00323	B-Cell Non-Hodgkin's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00291	Melanoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01038	B-Cell Non-Hodgkin's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00607	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00315	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00362	Burkitt's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00193	Colorectal Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01144	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00465	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00293	Small Cell Lung Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01194	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00466	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00040	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01181	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00238	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01032	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00287	B-Lymphoblastic Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00235	Kidney Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00358	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00486	Squamous Cell Lung Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01172	Acute Myeloid Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00587	Biliary Tract Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01180	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00488	Colorectal Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00242	Osteosarcoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00502	B-Lymphoblastic Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00247	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00325	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01210	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00018	Acute Myeloid Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00616	Hepatocellular Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01061	Oral Cavity Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00271	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01027	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00566	Oral Cavity Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00306	Non-Small Cell Lung Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00380	Acute Myeloid Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00361	Non-Small Cell Lung Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01031	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00045	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01025	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00448	B-Cell Non-Hodgkin's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00316	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00349	Esophageal Squamous Cell Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00274	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00083	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00302	Other Solid Cancers	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01018	Hodgkin's Lymphoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00243	Other Solid Cancers	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00381	Cervical Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00531	Pancreatic Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00192	Colorectal Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01735	Biliary Tract Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01617	Endometrial Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00168	Head and Neck Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01470	Acute Myeloid Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01412	Oral Cavity Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01368	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01578	Bladder Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00008	Ovarian Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01611	Endometrial Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00158	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01573	Plasma Cell Myeloma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01779	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01767	Squamous Cell Lung Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01494	Glioblastoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01691	Chronic Myelogenous Leukemia	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01433	Kidney Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01454	Kidney Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01321	Pancreatic Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00171	Colorectal Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM00162	Biliary Tract Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01343	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.D1359N	SIDM01443	Gastric Carcinoma	GDSC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1389
p.F15L	DO234363	ESAD	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.3056
p.S1815G	DO233168	GACA	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.25
p.S1815G	DO233168	GACA	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1111
p.A1839V	DO233864	GACA	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.25
p.E1563K	DO11854	GBM	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.0833
p.Q969L	DO228284	LICA	ICGC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation rewiring degron network	0.1944
p.P1488T	DO231954	LICA	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation altering degron motif	0.5919
p.A1842S	DO228474	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation altering degron motif	0.7588
p.A1842S	DO228806	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation altering degron motif	0.7588
p.H1360Q	DO228900	LICA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.1667
p.S1828R	DO229029	LICA	ICGC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.25
p.P1502T	DO229027	LICA	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1111
p.A1365D	DO229035	LICA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation rewiring degron network	0.3056
p.Q1854K	DO229045	LICA	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1111
p.S1626R	DO229045	LICA	ICGC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation altering degron motif	0.7427
p.V1368A	DO50886	LICA	ICGC	LEVFTE	LIG_APCC_ABBA_1	1366:1371	Mutation altering degron motif	0.6936
p.A15V	DO44864	LICA	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.3056
p.Q17L	DO219577	LIHC	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation altering degron motif	0.7765
p.V1567I	DO228372	MALY	ICGC	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1944
p.P1840S	DO220886	MELA	ICGC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.2778
p.A23T	DO232761	PBCA	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.25
p.S1483N	DO218861	SKCA	ICGC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.2222
p.E19D	DO37431	SKCM	ICGC	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation altering degron motif	0.6758
p.G1797V	DO229208	THCA	ICGC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.1667
p.M967I	SIDM01293	Colorectal Carcinoma	GDSC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation rewiring degron network	0.25
p.G1618D	SIDM00072	Non-Cancerous	GDSC	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1667
p.G1793S	SIDM00129	Melanoma	GDSC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0556
p.G1793S	G-MEL	skin	COSMIC	PFSSS	DEG_SPOP_SBC_1	1803:1807	Mutation rewiring degron network	0.0556
p.R1499S	SIDM00386	Ewing's Sarcoma	GDSC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1944
p.R1499S	SIDM00515	Melanoma	GDSC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1944
p.R1499S	ACH-000391	Bone Cancer	CCLE	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1944
p.R1499S	MHH-ES-1	bone	COSMIC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1944
p.R1499S	COLO-800	skin	COSMIC	LPYTPPLE	DEG_SCF_FBW7_2	1487:1494	Mutation rewiring degron network	0.1944
p.G1830S	SIDM01113	Other Sarcomas	GDSC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.1944
p.G1830S	ACH-000939	Sarcoma	CCLE	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.1944
p.G1830S	SK-UT-1	soft tissue	COSMIC	PFTTPANT	DEG_SCF_FBW7_1	1818:1825	Mutation rewiring degron network	0.1944
p.A1842D	SIDM00893	Breast Carcinoma	GDSC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation altering degron motif	0.7793
p.A1842D	ACH-000536	Breast Cancer	CCLE	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation altering degron motif	0.7793
p.A1842D	BT-20	breast	COSMIC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation altering degron motif	0.7793
p.D1851Y	SIDM00543	Melanoma	GDSC	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.D1851Y	ACH-002120	Skin Cancer	CCLE	APSTS	DEG_SPOP_SBC_1	1842:1846	Mutation rewiring degron network	0.1944
p.L960M	SIDM00228	Thyroid Gland Carcinoma	GDSC	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.711
p.L960M	ACH-000897	Thyroid Cancer	CCLE	VRNNLTVMD	DEG_APCC_DBOX_1	956:964	Mutation altering degron motif	0.711
p.G6E	ACH-000614	Skin Cancer	CCLE	AVSTS	DEG_SPOP_SBC_1	16:20	Mutation rewiring degron network	0.0556
p.R1617G	ACH-001190	Skin Cancer	CCLE	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1389
p.I1634T	ACH-001536	Bile Duct Cancer	CCLE	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation rewiring degron network	0.1667
p.S1628F	ACH-001566	Skin Cancer	CCLE	VNSSS	DEG_SPOP_SBC_1	1624:1628	Mutation altering degron motif	0.7982
p.W1564S	ACH-001609	Brain Cancer	CCLE	PGSST	DEG_SPOP_SBC_1	1572:1576	Mutation rewiring degron network	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons

TMEM131

UniProt ID: Q92545

Entrez ID: 23505

Protein name: Transmembrane protein 131 (Protein RW1)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for TMEM131 in