DegronMD - Q96L93(KIF16B)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.G1048V	TCGA-05-4427	LUAD	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1111
p.G1048V	DO23666	LUAD	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1111
p.M1027I	TCGA-24-2295	OV	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027I	DO32173	OV	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.K304M	TCGA-2Z-A9JL	KIRP	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation substituting flanking lysine	0.3611
p.K304M	DO219675	KIRP	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation substituting flanking lysine	0.3611
p.R163L	TCGA-34-2596	LUSC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1389
p.R163L	DO26508	LUSC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1389
p.T577I	TCGA-3B-A9HS	SARC	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation blocking phosphorylation signal	0.6389
p.T577I	DO219933	SARC	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation blocking phosphorylation signal	0.6389
p.E156K	TCGA-3P-A9WA	OV	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.E156K	TCGA-AZ-4315	COAD	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.E156K	TCGA-B5-A11E	UCEC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.E156K	DO8842	COAD	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.E156K	DO50655	OV	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.E156K	DO41644	UCEC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.7022
p.M590L	TCGA-50-5946	LUAD	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.5999
p.M590L	DO24556	LUAD	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.5999
p.E1028D	TCGA-51-6867	LUSC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.2222
p.E1028D	DO26477	LUSC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.2222
p.S1041N	TCGA-68-7757	LUSC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.3056
p.S1041N	DO26886	LUSC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.3056
p.E789K	TCGA-68-A59J	LUSC	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1111
p.E789K	TCGA-NC-A5HG	LUSC	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1111
p.E789K	DO49085	LUSC	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1111
p.E789K	DO45448	LUSC	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1111
p.V158M	TCGA-85-8071	LUSC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.2778
p.V158M	DO26755	LUSC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.2778
p.R798W	TCGA-85-A4CL	LUSC	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.8634
p.R798W	DO45454	LUSC	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.8634
p.D812Y	TCGA-85-A511	LUSC	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1389
p.D812Y	DO45509	LUSC	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1389
p.V308M	TCGA-A6-6653	COAD	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.6097
p.V308M	DO10373	COAD	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.6097
p.V308M	DO220856	MELA	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.6097
p.R145Q	TCGA-AA-A00N	COAD	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-AG-A002	READ	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-AJ-A3EL	UCEC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-AJ-A5DW	UCEC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-AN-A046	BRCA	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-AX-A05Z	UCEC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-CA-6717	COAD	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	TCGA-D1-A17Q	UCEC	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO1285	BRCA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO9876	COAD	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO8264	COAD	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO222762	COCA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO36556	READ	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO40884	UCEC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO50075	UCEC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO41542	UCEC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	DO41903	UCEC	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.R145Q	MCC13	skin	COSMIC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1667
p.L1101V	TCGA-AD-6548	COAD	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.3056
p.L1101V	DO9586	COAD	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.3056
p.S1038N	TCGA-AP-A1DK	UCEC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation altering degron motif	0.7069
p.S1038N	DO42033	UCEC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation altering degron motif	0.7069
p.K303N	TCGA-AX-A06F	UCEC	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation substituting flanking lysine	0.3333
p.K303N	DO41752	UCEC	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation substituting flanking lysine	0.3333
p.E1106D	TCGA-AX-A0J0	UCEC	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1667
p.E1106D	DO41133	UCEC	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1667
p.A588T	TCGA-AX-A1CE	UCEC	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.6028
p.A588T	DO42280	UCEC	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.6028
p.H1022Q	TCGA-CR-6474	HNSC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.0556
p.H1022Q	DO14542	HNSC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.0556
p.R583S	TCGA-D9-A148	SKCM	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.7427
p.R583S	DO37971	SKCM	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.7427
p.R311S	TCGA-D9-A148	SKCM	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.6316
p.R311S	DO37971	SKCM	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.6316
p.E599K	TCGA-DK-A1AC	BLCA	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.0833
p.E599K	DO514	BLCA	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.0833
p.G595R	TCGA-DU-6392	LGG	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.G595R	DO22237	LGG	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.G595R	SIDM00214	Colorectal Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.G595R	SNU-407	large intestine	COSMIC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.S1100G	TCGA-E9-A1RF	BRCA	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.8104
p.S1100G	DO2665	BRCA	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.8104
p.S1108L	TCGA-EB-A5SG	SKCM	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation blocking phosphorylation signal	0.5556
p.S1108L	DO48726	SKCM	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation blocking phosphorylation signal	0.5556
p.R311M	TCGA-EE-A2GT	SKCM	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.7521
p.R311M	TCGA-ER-A19B	SKCM	TCGA	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.7521
p.R311M	DO47491	SKCM	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.7521
p.R311M	DO37946	SKCM	ICGC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation altering degron motif	0.7521
p.A1105G	TCGA-EE-A2GU	SKCM	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1944
p.A1105G	DO37639	SKCM	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1944
p.L802M	TCGA-EE-A3AA	SKCM	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.5999
p.L802M	DO222632	MELA	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.5999
p.L802M	DO37571	SKCM	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.5999
p.G1026D	TCGA-EO-A22R	UCEC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1667
p.G1026D	DO42713	UCEC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1667
p.G595E	TCGA-FW-A3R5	SKCM	TCGA	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.G595E	DO37406	SKCM	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.1944
p.R798L	TCGA-HU-A4H4	STAD	TCGA	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.8428
p.R798L	DO47721	STAD	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.8428
p.G1042S	TCGA-UF-A7JA	HNSC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.2778
p.G1042S	DO52112	HNSC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.2778
p.S166L	TCGA-VQ-A91N	STAD	TCGA	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.0556
p.S166L	DO222351	STAD	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.0556
p.S1047L	TCGA-VS-A8EB	CESC	TCGA	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation blocking phosphorylation signal	0.5833
p.S1047L	DO51617	CESC	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation blocking phosphorylation signal	0.5833
p.S1099F	TCGA-W3-AA1V	SKCM	TCGA	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.9093
p.S1099F	DO51276	SKCM	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.9093
p.R164W	DO225109	BRCA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1111
p.L151V	DO225132	BRCA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation altering degron motif	0.5654
p.G810R	DO222990	BTCA	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1944
p.S580L	DO227646	COCA	ICGC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation blocking phosphorylation signal	0.7222
p.M1027T	DO229010	COCA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027T	DO229013	COCA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027T	DO229016	COCA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027T	DO229003	COCA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027T	DO229005	COCA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.M1027T	DO35192	PACA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.1944
p.G1090W	DO233694	GACA	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1667
p.A1105D	DO229015	LICA	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation rewiring degron network	0.1944
p.A1037D	DO229031	LICA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation altering degron motif	0.6682
p.A1037D	DO229035	LICA	ICGC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation altering degron motif	0.6682
p.A1097T	DO228414	MALY	ICGC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.6028
p.R163W	DO222880	MELA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.1389
p.R157C	DO49422	PACA	ICGC	LEIYNE	LIG_APCC_ABBA_1	151:156	Mutation rewiring degron network	0.3056
p.D812V	DO218858	SKCA	ICGC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1389
p.R583H	SIDM00557	Neuroblastoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00586	Hepatocellular Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00608	Plasma Cell Myeloma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00588	Oral Cavity Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01242	Melanoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01011	B-Cell Non-Hodgkin's Lymphoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01247	Burkitt's Lymphoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00596	Endometrial Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00278	Esophageal Squamous Cell Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00252	Biliary Tract Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00214	Colorectal Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00242	Osteosarcoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00612	Glioma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00609	Kidney Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00996	Thyroid Gland Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01551	Gastric Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01460	Glioma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00163	Biliary Tract Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM01450	Gastric Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.R583H	SIDM00016	Neuroblastoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.8244
p.G811E	SIDM00422	Hodgkin's Lymphoma	GDSC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1667
p.G811E	ACH-001203	Lymphoma	CCLE	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1667
p.G811E	SUP-HD1	haematopoietic and lymphoid tissue	COSMIC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1667
p.H1022R	SIDM00454	Rhabdomyosarcoma	GDSC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.0556
p.H1022R	SIDM00309	Mesothelioma	GDSC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.0556
p.H1022R	SIDM01664	Prostate Carcinoma	GDSC	QRQKLASLN	DEG_APCC_DBOX_1	1032:1040	Mutation rewiring degron network	0.0556
p.N585T	SIDM01117	Small Cell Lung Carcinoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation altering degron motif	0.5944
p.S1099T	SIDM00656	Burkitt's Lymphoma	GDSC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.7116
p.S1099T	ACH-000944	Lymphoma	CCLE	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.7116
p.S1099T	NAMALWA	haematopoietic and lymphoid tissue	COSMIC	VASSS	DEG_SPOP_SBC_1	1096:1100	Mutation altering degron motif	0.7116
p.F572L	SIDM00581	Glioblastoma	GDSC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.0556
p.F572L	ACH-000738	Brain Cancer	CCLE	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.0556
p.F572L	GB-1	central nervous system	COSMIC	SRENLSAVM	DEG_APCC_DBOX_1	582:590	Mutation rewiring degron network	0.0556
p.R808S	SIDM00645	Non-Small Cell Lung Carcinoma	GDSC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.25
p.R808S	NCI-H1355	lung	COSMIC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.25
p.N298D	SIDM00156	Neuroblastoma	GDSC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.0833
p.N298D	ACH-002285	Neuroblastoma	CCLE	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.0833
p.N298D	NB7	autonomic ganglia	COSMIC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.0833
p.D793H	SIDM00888	Other Solid Cancers	GDSC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.2222
p.R803L	SIDM00775	Non-Small Cell Lung Carcinoma	GDSC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.7316
p.R803L	ACH-000785	Lung Cancer	CCLE	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.7316
p.R803L	NCI-H2126	lung	COSMIC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation altering degron motif	0.7316
p.A301S	SIDM00292	Small Cell Lung Carcinoma	GDSC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.1667
p.A301S	ACH-002077	Lung Cancer	CCLE	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.1667
p.A301S	LU-165	lung	COSMIC	FVPYRD	LIG_APCC_ABBA_1	307:312	Mutation rewiring degron network	0.1667
p.R792S	SIDM01018	Hodgkin's Lymphoma	GDSC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1944
p.R792S	ACH-000815	Lymphoma	CCLE	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1944
p.R792S	KM-H2	haematopoietic and lymphoid tissue	COSMIC	IRESLLRVK	DEG_APCC_DBOX_1	797:805	Mutation rewiring degron network	0.1944

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KIF16B

UniProt ID: Q96L93

Entrez ID: 55614

Protein name: Kinesin-like protein KIF16B (Sorting nexin-23)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KIF16B in