DegronMD - Q99715(COL12A1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N1849K	TCGA-10-0930	OV	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1667
p.N1849K	DO32113	OV	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1667
p.P772S	TCGA-44-3917	LUAD	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.25
p.P772S	DO25242	LUAD	ICGC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.25
p.P2570Q	TCGA-46-3765	LUSC	TCGA	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.2222
p.P2570Q	DO26959	LUSC	ICGC	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.2222
p.P2570Q	ACH-000773	Lymphoma	CCLE	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.2222
p.D1865Y	TCGA-55-8204	LUAD	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1667
p.D1865Y	DO45322	LUAD	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1667
p.R1863L	TCGA-66-2782	LUSC	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.R1863L	DO26680	LUSC	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.V822F	TCGA-86-8073	LUAD	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.25
p.V822F	DO23624	LUAD	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.25
p.D2046N	TCGA-A2-A0EQ	BRCA	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0556
p.D2046N	DO4773	BRCA	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0556
p.A1867T	TCGA-A6-5661	COAD	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1111
p.A1867T	DO8634	COAD	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1111
p.A1867T	ACH-000979	Prostate Cancer	CCLE	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1111
p.P838T	TCGA-A6-5661	COAD	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.0833
p.P838T	DO8634	COAD	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.0833
p.K831T	TCGA-AA-3848	COAD	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.2778
p.K831T	DO9740	COAD	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.2778
p.R2025H	TCGA-AA-A00N	COAD	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1667
p.R2025H	DO9876	COAD	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1667
p.R2025H	DO45299	LIRI	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1667
p.P784T	TCGA-AG-A002	READ	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.3056
p.T827M	TCGA-AN-A049	BRCA	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	DO4305	BRCA	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00373	Endometrial Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00578	Neuroblastoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01197	Colorectal Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00304	Ovarian Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00592	Oral Cavity Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01029	Esophageal Squamous Cell Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00217	Colorectal Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00604	Oral Cavity Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01498	Acute Myeloid Leukemia	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01779	Gastric Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM00016	Neuroblastoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.T827M	SIDM01442	Glioma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7423
p.S2040N	TCGA-AP-A059	UCEC	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.2222
p.S2040N	DO41361	UCEC	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.2222
p.D945Y	TCGA-AP-A1E0	UCEC	TCGA	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation altering degron motif	0.7325
p.D945Y	DO43154	UCEC	ICGC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation altering degron motif	0.7325
p.L2568P	TCGA-AY-6197	COAD	TCGA	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.1667
p.L2568P	DO9956	COAD	ICGC	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.1667
p.V790A	TCGA-B5-A1MW	UCEC	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1389
p.V790A	DO42913	UCEC	ICGC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1389
p.R2056M	TCGA-BF-A1Q0	SKCM	TCGA	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.0833
p.R2056M	TCGA-BR-4184	STAD	TCGA	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.0833
p.R2056M	DO47374	SKCM	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.0833
p.R2056M	DO38328	STAD	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.0833
p.R776G	TCGA-BH-A1FC	BRCA	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation altering degron motif	0.7568
p.R776G	DO5661	BRCA	ICGC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation altering degron motif	0.7568
p.S3051R	TCGA-BR-4292	STAD	TCGA	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.1111
p.P825H	TCGA-BR-6452	STAD	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7694
p.P825H	TCGA-EE-A3AD	SKCM	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7694
p.P825H	DO37707	SKCM	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7694
p.P825H	DO38404	STAD	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation altering degron motif	0.7694
p.G2027E	TCGA-CG-4306	STAD	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.2222
p.G2027E	DO38567	STAD	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.2222
p.P3053A	TCGA-CG-4444	STAD	TCGA	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.0556
p.I2081T	TCGA-CG-5722	STAD	TCGA	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.1389
p.I2081T	DO38244	STAD	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.1389
p.L1860F	TCGA-CG-5733	STAD	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.3056
p.L1860F	DO38551	STAD	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.3056
p.A2566T	TCGA-CM-6674	COAD	TCGA	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.1111
p.A2566T	DO10092	COAD	ICGC	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.1111
p.G839R	TCGA-D3-A1Q5	SKCM	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.0556
p.G839R	DO37827	SKCM	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.0556
p.W1864L	TCGA-D3-A2J8	SKCM	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1944
p.W1864L	DO37778	SKCM	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.1944
p.M830T	TCGA-DD-A3A9	LIHC	TCGA	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.3056
p.M830T	DO44888	LIHC	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.3056
p.I793T	TCGA-ED-A7XO	LIHC	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.0556
p.I793T	DO48496	LIHC	ICGC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.0556
p.P3040S	TCGA-EE-A182	SKCM	TCGA	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.6752
p.W2045C	TCGA-EE-A183	SKCM	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.W2045C	DO37715	SKCM	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.P3038L	TCGA-EE-A2GL	SKCM	TCGA	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.2778
p.R936M	TCGA-EE-A3AC	SKCM	TCGA	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.0833
p.R936M	DO37631	SKCM	ICGC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.0833
p.D785N	TCGA-EO-A22U	UCEC	TCGA	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.2778
p.D785N	DO43755	UCEC	ICGC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.2778
p.R1851I	TCGA-EO-A3B0	UCEC	TCGA	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.R1851I	DO219773	UCEC	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.T2022M	TCGA-VQ-A8PB	STAD	TCGA	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.T2022M	DO6507	CLLE	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.T2022M	DO231708	LINC	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.T2022M	DO51766	STAD	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0833
p.N3031Y	TCGA-VQ-A8PO	STAD	TCGA	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.0833
p.P2061S	DO224944	BRCA	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.2222
p.I2081V	DO50332	ESAD	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.1389
p.P2074S	DO234170	ESAD	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation altering degron motif	0.6752
p.Y2577H	DO234199	ESAD	ICGC	PPSY	ITCH	2574:2577	Mutation altering degron motif	0.7229
p.P2061H	DO234393	ESAD	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.2222
p.P2061H	ACH-001973	Metastasis	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.2222
p.Q2083E	DO233064	GACA	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.0833
p.T2037K	DO228974	LICA	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.3056
p.P838Q	DO229022	LICA	ICGC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.0833
p.G2035C	DO50843	LICA	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation altering degron motif	0.6489
p.N952I	DO45209	LIRI	ICGC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.2778
p.A2044G	DO228325	MALY	ICGC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1111
p.L2582F	DO228365	MALY	ICGC	PPSY	ITCH	2574:2577	Mutation rewiring degron network	0.1944
p.P2575L	DO222363	MELA	ICGC	PPSY	ITCH	2574:2577	Mutation altering degron motif	0.7582
p.I2067V	DO27885	ORCA	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation altering degron motif	0.5965
p.I2067V	SIDM01739	Small Cell Lung Carcinoma	GDSC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation altering degron motif	0.5965
p.P1855L	DO218882	SKCA	ICGC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation altering degron motif	0.7582
p.D2068Y	DO229227	THCA	ICGC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation altering degron motif	0.6214
p.V792I	SIDM01293	Colorectal Carcinoma	GDSC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.0833
p.R2021Q	SIDM00319	Melanoma	GDSC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0556
p.R2021Q	SIDM00654	Small Cell Lung Carcinoma	GDSC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0556
p.R2021Q	SIDM00210	Ovarian Carcinoma	GDSC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.0556
p.E789D	SIDM01175	Other Sarcomas	GDSC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.E789D	ACH-002309	Sarcoma	CCLE	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.E789D	SW684	soft tissue	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.P817T	SIDM00741	Small Cell Lung Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1111
p.P817T	ACH-000431	Lung Cancer	CCLE	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1111
p.P817T	NCI-H1694	lung	COSMIC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1111
p.R1851K	SIDM00193	Colorectal Carcinoma	GDSC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.R1851K	ACH-000991	Colon/Colorectal Cancer	CCLE	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.R1851K	SNU-81	large intestine	COSMIC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.S2026N	SIDM00660	Colorectal Carcinoma	GDSC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1944
p.S2026N	ACH-000985	Colon/Colorectal Cancer	CCLE	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1944
p.S2026N	LS-411N	large intestine	COSMIC	LRVFGE	LIG_APCC_ABBA_1	2031:2036	Mutation rewiring degron network	0.1944
p.P3041L	SIDM01099	Neuroblastoma	GDSC	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.P3041L	SIDM01130	Squamous Cell Lung Carcinoma	GDSC	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.P3041L	ACH-000341	Neuroblastoma	CCLE	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.P3041L	ACH-000395	Lung Cancer	CCLE	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.P3041L	NCI-H520	lung	COSMIC	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.P3041L	SK-N-FI	autonomic ganglia	COSMIC	PPGY	ITCH	3040:3043	Mutation altering degron motif	0.7582
p.G2064V	SIDM00761	Small Cell Lung Carcinoma	GDSC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064V	ACH-000752	Lung Cancer	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064V	ACH-000966	Ovarian Cancer	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064V	NCI-H196	lung	COSMIC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064C	SIDM00761	Small Cell Lung Carcinoma	GDSC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064C	ACH-000752	Lung Cancer	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064C	ACH-000966	Ovarian Cancer	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.G2064C	NCI-H196	lung	COSMIC	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.T769I	SIDM01149	Small Cell Lung Carcinoma	GDSC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.T769I	ACH-001365	Lung Cancer	CCLE	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.T769I	NCI-H847	lung	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.W834S	SIDM00966	Ovarian Carcinoma	GDSC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1944
p.W834S	ACH-002182	Ovarian Cancer	CCLE	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1944
p.W834S	OVCA433	ovary	COSMIC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1944
p.S765N	SIDM00683	Prostate Carcinoma	GDSC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation blocking phosphorylation signal	0.5
p.S765N	ACH-000977	lymph node	CCLE	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation blocking phosphorylation signal	0.5
p.S765N	LNCaP-Clone-FGC	prostate	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation blocking phosphorylation signal	0.5
p.V937A	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.1111
p.V937A	ACH-000886	Lung Cancer	CCLE	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.1111
p.V937A	NCI-H2009	lung	COSMIC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.1111
p.V1862A	SIDM01559	Melanoma	GDSC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.25
p.V1862A	SIDM00159	Biliary Tract Carcinoma	GDSC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.25
p.G2075V	ACH-000712	Lung Cancer	CCLE	DPIDEYTTVP	CBL_PTK	2065:2074	Mutation rewiring degron network	0.3056
p.D785Y	ACH-000769	Lung Cancer	CCLE	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.2778
p.P771R	ACH-000906	Ovarian Cancer	CCLE	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.2222
p.R1863C	ACH-002066	Sarcoma	CCLE	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.2222
p.Y779N	COR-L88	lung	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation altering degron motif	0.7059
p.Y935C	CAL-120	breast	COSMIC	DVDTGE	DEG_Kelch_Keap1_1	945:950	Mutation rewiring degron network	0.0556
p.P3037L	NCI-H520	lung	COSMIC	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.25
p.P3037L	SK-N-FI	autonomic ganglia	COSMIC	PPGY	ITCH	3040:3043	Mutation rewiring degron network	0.25
p.S837N	LS-411N	large intestine	COSMIC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1111
p.P819S	SNU-1040	large intestine	COSMIC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.1667
p.P1852L	NCI-H520	lung	COSMIC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.25
p.P1852L	SK-N-FI	autonomic ganglia	COSMIC	PSTST	DEG_SPOP_SBC_1	1855:1859	Mutation rewiring degron network	0.25
p.V778A	COR-L88	lung	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation altering degron motif	0.6936
p.G822V	NCI-H2196	lung	COSMIC	PTTST	DEG_SPOP_SBC_1	825:829	Mutation rewiring degron network	0.25
p.P769L	NB14	autonomic ganglia	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation rewiring degron network	0.1667
p.V777I	SNG-M	endometrium	COSMIC	RRRTLENLI	DEG_APCC_DBOX_1	775:783	Mutation altering degron motif	0.7076

DegronMD: protein-targeted degradation, mutation and drug response to degrons

COL12A1

UniProt ID: Q99715

Entrez ID: 1303

Protein name: Collagen alpha-1(XII) chain

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for COL12A1 in