DegronMD - Q9UHR4(BAIAP2L1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.T502M	TCGA-26-5136	GBM	TCGA	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.1389
p.T502M	DO11471	GBM	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.1389
p.E244K	TCGA-36-2547	OV	TCGA	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.2778
p.E244K	TCGA-36-2547	OV	TCGA	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.0556
p.E244K	DO30990	OV	ICGC	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.2778
p.E244K	DO30990	OV	ICGC	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.0556
p.G446V	TCGA-50-6594	LUAD	TCGA	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.0556
p.G446V	TCGA-50-6594	LUAD	TCGA	PPDY	ITCH	436:439	Mutation rewiring degron network	0.1389
p.G446V	DO24275	LUAD	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.0556
p.G446V	DO24275	LUAD	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.1389
p.E441G	TCGA-AD-6964	COAD	TCGA	PPDY	ITCH	436:439	Mutation rewiring degron network	0.2778
p.E441G	DO8360	COAD	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.2778
p.T412M	TCGA-AJ-A3EK	UCEC	TCGA	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation altering degron motif	0.8534
p.T412M	TCGA-AJ-A3EK	UCEC	TCGA	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation altering degron motif	0.8534
p.T412M	DO233737	GACA	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation altering degron motif	0.8534
p.T412M	DO233737	GACA	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation altering degron motif	0.8534
p.T412M	DO41584	UCEC	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation altering degron motif	0.8534
p.T412M	DO41584	UCEC	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation altering degron motif	0.8534
p.S395L	TCGA-AJ-A3EL	UCEC	TCGA	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5278
p.S395L	DO41542	UCEC	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5278
p.D438N	TCGA-AP-A1DV	UCEC	TCGA	PPDY	ITCH	436:439	Mutation altering degron motif	0.5821
p.D438N	TCGA-VQ-A8PP	STAD	TCGA	PPDY	ITCH	436:439	Mutation altering degron motif	0.5821
p.D438N	DO51774	STAD	ICGC	PPDY	ITCH	436:439	Mutation altering degron motif	0.5821
p.D438N	DO43186	UCEC	ICGC	PPDY	ITCH	436:439	Mutation altering degron motif	0.5821
p.T397M	TCGA-BR-4257	STAD	TCGA	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5833
p.T397M	DO38683	STAD	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5833
p.S422N	TCGA-BR-8487	STAD	TCGA	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5278
p.S422N	TCGA-BR-8487	STAD	TCGA	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation blocking phosphorylation signal	0.6111
p.S422N	DO47867	STAD	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5278
p.S422N	DO47867	STAD	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation blocking phosphorylation signal	0.6111
p.P415H	TCGA-EE-A2GK	SKCM	TCGA	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation altering degron motif	0.6583
p.P415H	DO37738	SKCM	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation altering degron motif	0.6583
p.M445I	TCGA-EE-A2ME	SKCM	TCGA	PPDY	ITCH	436:439	Mutation rewiring degron network	0.1667
p.M445I	DO38011	SKCM	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.1667
p.P253L	TCGA-ER-A194	SKCM	TCGA	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.3056
p.P253L	TCGA-ER-A194	SKCM	TCGA	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.3056
p.P253L	DO47646	SKCM	ICGC	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.3056
p.P253L	DO47646	SKCM	ICGC	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.3056
p.A466V	TCGA-FI-A2D5	UCEC	TCGA	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1667
p.A466V	DO41331	UCEC	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1667
p.D438G	TCGA-G2-AA3F	BLCA	TCGA	PPDY	ITCH	436:439	Mutation altering degron motif	0.6087
p.D438G	DO51885	BLCA	ICGC	PPDY	ITCH	436:439	Mutation altering degron motif	0.6087
p.I510T	TCGA-GD-A3OS	BLCA	TCGA	IIR	DEG_APCC_TPR_1	509:511	Mutation altering degron motif	0.7078
p.I510T	DO598	BLCA	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation altering degron motif	0.7078
p.S506W	TCGA-UF-A7JV	HNSC	TCGA	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.25
p.S506W	DO50010	HNSC	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.25
p.V418M	TCGA-XK-AAIW	PRAD	TCGA	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.1944
p.V418M	TCGA-XK-AAIW	PRAD	TCGA	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.2778
p.V418M	DO51407	PRAD	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.1944
p.V418M	DO51407	PRAD	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.2778
p.S460T	DO229003	COCA	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	DO229505	LAML	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00578	Neuroblastoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00434	Plasma Cell Myeloma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00353	Other Sarcomas	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00435	Acute Myeloid Leukemia	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00600	Thyroid Gland Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00323	B-Cell Non-Hodgkin's Lymphoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00370	T-Lymphoblastic Leukemia	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00555	Glioblastoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00463	T-Lymphoblastic Leukemia	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00394	Cervical Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00060	Ovarian Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00287	B-Lymphoblastic Leukemia	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01045	Endometrial Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00487	Colorectal Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00505	Pancreatic Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00550	Esophageal Squamous Cell Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00498	Colorectal Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00410	Other Blood Cancers	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00283	B-Cell Non-Hodgkin's Lymphoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00280	Gastric Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00807	Bladder Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00655	Other Solid Cancers	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01217	Other Blood Cancers	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00986	Head and Neck Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01025	Esophageal Squamous Cell Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00503	Gastric Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01018	Hodgkin's Lymphoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00575	Glioma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00192	Colorectal Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01449	Pancreatic Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01393	Gastric Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01578	Bladder Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01336	Glioblastoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01472	Hepatocellular Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01779	Gastric Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01435	Hepatocellular Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01446	Glioblastoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00164	Biliary Tract Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM00500	Colorectal Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01587	Bladder Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01574	Plasma Cell Myeloma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.S460T	SIDM01343	Gastric Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.6005
p.E245K	DO233155	GACA	ICGC	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.3056
p.E245K	DO233155	GACA	ICGC	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.0833
p.E404G	DO233760	GACA	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation altering degron motif	0.7199
p.A449D	DO228976	LICA	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1389
p.A449D	DO228976	LICA	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0556
p.L400M	DO229025	LICA	ICGC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.2222
p.L400M	DO229025	LICA	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.0556
p.P508T	DO229031	LICA	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.3056
p.P435T	DO229006	LICA	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.3056
p.A456D	DO229009	LICA	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation altering degron motif	0.7793
p.L426S	DO231754	LINC	ICGC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.0556
p.L426S	DO231754	LINC	ICGC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0556
p.D504V	DO45145	LIRI	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.1944
p.D450N	DO231040	LUSC	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1667
p.V501E	DO233293	NACA	ICGC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.1111
p.D450V	DO233298	NACA	ICGC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1667
p.P499L	SIDM02035	Colorectal Carcinoma	GDSC	IIR	DEG_APCC_TPR_1	509:511	Mutation rewiring degron network	0.0556
p.V424M	SIDM02013	Colorectal Carcinoma	GDSC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1111
p.A448T	SIDM01163	Non-Small Cell Lung Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01163	Non-Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01649	Non-Cancerous	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01649	Non-Cancerous	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00388	B-Cell Non-Hodgkin's Lymphoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00632	Non-Cancerous	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00632	Non-Cancerous	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01129	Small Cell Lung Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01129	Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00263	Ewing's Sarcoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00263	Ewing's Sarcoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00934	Pancreatic Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00934	Pancreatic Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01081	Oral Cavity Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01081	Oral Cavity Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00143	Small Cell Lung Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00143	Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00817	Kidney Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00817	Kidney Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00342	T-Lymphoblastic Leukemia	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00342	T-Lymphoblastic Leukemia	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00756	Non-Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01050	Biliary Tract Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01050	Biliary Tract Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00711	Squamous Cell Lung Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00711	Squamous Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00736	Non-Cancerous	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00736	Non-Cancerous	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01170	Ovarian Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01170	Ovarian Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00519	Mesothelioma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00519	Mesothelioma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00184	Melanoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00184	Melanoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM00490	Glioma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM00490	Glioma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.A448T	SIDM01772	Mesothelioma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1111
p.A448T	SIDM01772	Mesothelioma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0833
p.S394L	SIDM00938	Breast Carcinoma	GDSC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5
p.S394L	ACH-000902	Breast Cancer	CCLE	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5
p.S394L	CAL-148	breast	COSMIC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation blocking phosphorylation signal	0.5
p.L440F	SIDM00577	Neuroblastoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.3056
p.L440F	ACH-001603	Neuroblastoma	CCLE	PPDY	ITCH	436:439	Mutation rewiring degron network	0.3056
p.L440F	NH-12	autonomic ganglia	COSMIC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.3056
p.N403D	SIDM00267	Biliary Tract Carcinoma	GDSC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.3056
p.N403D	SIDM00267	Biliary Tract Carcinoma	GDSC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1389
p.N403D	ACH-002044	Head and Neck Cancer	CCLE	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.3056
p.N403D	ACH-002044	Head and Neck Cancer	CCLE	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1389
p.N403D	ACH-002312	Gallbladder Cancer	CCLE	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.3056
p.N403D	ACH-002312	Gallbladder Cancer	CCLE	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1389
p.N403D	TGBC24TKB	biliary tract	COSMIC	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.3056
p.N403D	TGBC24TKB	biliary tract	COSMIC	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1389
p.V269M	SIDM01172	Acute Myeloid Leukemia	GDSC	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.1111
p.V269M	ACH-000146	Leukemia	CCLE	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.1111
p.V269M	THP-1	haematopoietic and lymphoid tissue	COSMIC	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.1111
p.I243F	SIDM00249	Esophageal Squamous Cell Carcinoma	GDSC	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.25
p.I243F	ACH-000353	Esophageal Cancer	CCLE	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.25
p.I243F	TE-15	oesophagus	COSMIC	IKTPAST	DEG_SCF_FBW7_1	246:252	Mutation rewiring degron network	0.25
p.A449T	SIDM00118	Colorectal Carcinoma	GDSC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1389
p.A449T	SIDM00118	Colorectal Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0556
p.A449T	ACH-001081	Colon/Colorectal Cancer	CCLE	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1389
p.A449T	ACH-001081	Colon/Colorectal Cancer	CCLE	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0556
p.A449T	HCC2998	large intestine	COSMIC	ARTTS	DEG_SPOP_SBC_1	456:460	Mutation rewiring degron network	0.1389
p.A449T	HCC2998	large intestine	COSMIC	PPDY	ITCH	436:439	Mutation rewiring degron network	0.0556
p.D438E	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	PPDY	ITCH	436:439	Mutation altering degron motif	0.5647
p.D438E	ACH-000845	Lung Cancer	CCLE	PPDY	ITCH	436:439	Mutation altering degron motif	0.5647
p.E402Q	ACH-000923	Lymphoma	CCLE	ETEAVTVPTP	DEG_COP1_1	404:413	Mutation rewiring degron network	0.2778
p.E402Q	ACH-000923	Lymphoma	CCLE	VPTPSPT	DEG_SCF_FBW7_1	410:416	Mutation rewiring degron network	0.1111
p.E265K	ACH-001608	Brain Cancer	CCLE	VSGTPQAS	DEG_SCF_FBW7_1	254:261	Mutation rewiring degron network	0.2222

DegronMD: protein-targeted degradation, mutation and drug response to degrons

BAIAP2L1

UniProt ID: Q9UHR4

Entrez ID: 55971

Protein name: Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for BAIAP2L1 in