DegronMD - Q9ULL0(KIAA1210)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.K614I	TCGA-06-5416	GBM	TCGA	PETTT	DEG_SPOP_SBC_1	602:606	Mutation substituting flanking lysine	0.2222
p.K614I	DO10880	GBM	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation substituting flanking lysine	0.2222
p.R1164M	TCGA-20-1683	OV	TCGA	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1389
p.R1164M	DO29720	OV	ICGC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1389
p.F389L	TCGA-33-4532	LUSC	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.1389
p.F389L	TCGA-BG-A222	UCEC	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.1389
p.F389L	DO26626	LUSC	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.1389
p.F389L	DO42977	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.1389
p.R311P	TCGA-43-8115	LUSC	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.6401
p.R311P	DO26440	LUSC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.6401
p.R1514M	TCGA-44-2655	LUAD	TCGA	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.25
p.R1514M	DO23557	LUAD	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.25
p.S1505T	TCGA-44-5644	LUAD	TCGA	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505T	DO25153	LUAD	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1244I	TCGA-44-6777	LUAD	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.25
p.S1244I	DO23645	LUAD	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.25
p.A1078T	TCGA-50-5930	LUAD	TCGA	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.0556
p.A1078T	DO25189	LUAD	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.0556
p.A1078T	DO229213	THCA	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.0556
p.K1235Q	TCGA-61-1998	OV	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.6944
p.K1235Q	DO28813	OV	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.6944
p.R309H	TCGA-69-7979	LUAD	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R309H	TCGA-HU-A4GC	STAD	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R309H	DO23874	LUAD	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R309H	DO47797	STAD	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R309H	SIDM00162	Biliary Tract Carcinoma	GDSC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R309H	ACH-000268	Bile Duct Cancer	CCLE	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.S1101Y	TCGA-73-4670	LUAD	TCGA	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.1667
p.S1101Y	TCGA-73-4670	LUAD	TCGA	PESTT	DEG_SPOP_SBC_1	1104:1108	Mutation rewiring degron network	0.25
p.S1101Y	DO25350	LUAD	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.1667
p.S1101Y	DO25350	LUAD	ICGC	PESTT	DEG_SPOP_SBC_1	1104:1108	Mutation rewiring degron network	0.25
p.G1250R	TCGA-73-A9RS	LUAD	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.0833
p.G1250R	DO51193	LUAD	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.0833
p.A1158D	TCGA-95-7043	LUAD	TCGA	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.A1158D	DO24739	LUAD	ICGC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.T380I	TCGA-A2-A0CQ	BRCA	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation altering degron motif	0.7078
p.T380I	DO3116	BRCA	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation altering degron motif	0.7078
p.M594I	TCGA-AA-3877	COAD	TCGA	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1111
p.M594I	DO7855	COAD	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1111
p.M594I	DO229470	SKCA	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1111
p.R310L	TCGA-AG-A002	READ	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.8428
p.S1379F	TCGA-AJ-A3EL	UCEC	TCGA	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7982
p.S1379F	TCGA-AN-A046	BRCA	TCGA	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7982
p.S1379F	DO1285	BRCA	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7982
p.S1379F	DO41542	UCEC	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7982
p.S1520I	TCGA-AN-A0FL	BRCA	TCGA	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.0833
p.S1520I	DO1836	BRCA	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.0833
p.P386S	TCGA-AP-A051	UCEC	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.2222
p.P386S	DO42673	UCEC	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.2222
p.Q1237H	TCGA-AP-A1E0	UCEC	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.647
p.Q1237H	DO43154	UCEC	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.647
p.S326Y	TCGA-AX-A05Z	UCEC	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0833
p.S326Y	TCGA-AX-A2HC	UCEC	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0833
p.S326Y	DO40884	UCEC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0833
p.S326Y	DO41572	UCEC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0833
p.S1230L	TCGA-AX-A2HC	UCEC	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1944
p.S1230L	DO41572	UCEC	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1944
p.S935F	TCGA-B5-A0JY	UCEC	TCGA	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.2222
p.S935F	DO43041	UCEC	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.2222
p.E595Q	TCGA-BK-A0C9	UCEC	TCGA	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1389
p.E595Q	DO41253	UCEC	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1389
p.P1225S	TCGA-D3-A1QA	SKCM	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.0556
p.P1225S	DO47469	SKCM	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.0556
p.D940N	TCGA-D3-A2JL	SKCM	TCGA	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.0833
p.D940N	TCGA-EE-A2GM	SKCM	TCGA	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.0833
p.D940N	DO37555	SKCM	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.0833
p.D940N	DO47278	SKCM	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.0833
p.R1514S	TCGA-D3-A3CE	SKCM	TCGA	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.25
p.R1514S	DO37405	SKCM	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.25
p.P317S	TCGA-D3-A51T	SKCM	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.5641
p.P317S	DO47389	SKCM	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.5641
p.P317S	SIDM00770	Small Cell Lung Carcinoma	GDSC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.5641
p.P317S	ACH-000559	Lung Cancer	CCLE	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.5641
p.P317S	NCI-H1836	lung	COSMIC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.5641
p.P1507L	TCGA-D3-A8GQ	SKCM	TCGA	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation altering degron motif	0.7582
p.P1507L	DO51246	SKCM	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation altering degron motif	0.7582
p.P392Q	TCGA-D9-A148	SKCM	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0556
p.P392Q	DO37971	SKCM	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0556
p.S381C	TCGA-DD-AAC8	LIHC	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation altering degron motif	0.7541
p.S381C	DO52193	LIHC	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation altering degron motif	0.7541
p.M507I	TCGA-DM-A282	COAD	TCGA	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.0833
p.M507I	DO9058	COAD	ICGC	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.0833
p.A1078S	TCGA-E6-A1LX	UCEC	TCGA	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.0556
p.A1078S	DO41020	UCEC	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.0556
p.S931L	TCGA-EB-A431	SKCM	TCGA	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7667
p.S931L	DO37671	SKCM	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation altering degron motif	0.7667
p.T383I	TCGA-ED-A4XI	LIHC	TCGA	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.3056
p.T383I	DO48505	LIHC	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.3056
p.E595K	TCGA-EE-A182	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1389
p.E595K	DO37814	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.1389
p.G609W	TCGA-EE-A29L	SKCM	TCGA	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.25
p.G609W	DO37835	SKCM	ICGC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.25
p.E486K	TCGA-EE-A2MF	SKCM	TCGA	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.1111
p.E486K	DO222491	MELA	ICGC	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.1111
p.E486K	DO51249	SKCM	ICGC	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.1111
p.V1375D	TCGA-EO-A22R	UCEC	TCGA	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7785
p.V1375D	DO42713	UCEC	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.7785
p.R311H	TCGA-EO-A22R	UCEC	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R311H	DO42713	UCEC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7133
p.R310Q	TCGA-EO-A3B0	UCEC	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7329
p.R310Q	DO219773	UCEC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.7329
p.Q1237K	TCGA-ER-A2NF	SKCM	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.5833
p.Q1237K	DO47451	SKCM	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation altering degron motif	0.5833
p.P1232S	TCGA-EY-A1G8	UCEC	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.25
p.P1232S	DO43578	UCEC	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.25
p.Q501H	TCGA-EY-A1G8	UCEC	TCGA	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.25
p.Q501H	DO43578	UCEC	ICGC	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation rewiring degron network	0.25
p.K1231N	TCGA-FB-AAPU	PAAD	TCGA	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation substituting flanking lysine	0.3333
p.K1231N	DO218966	PAAD	ICGC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation substituting flanking lysine	0.3333
p.T1091S	TCGA-FR-A2OS	SKCM	TCGA	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation altering degron motif	0.7116
p.T1091S	DO37876	SKCM	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation altering degron motif	0.7116
p.A1383D	TCGA-G4-6586	COAD	TCGA	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.2222
p.A1383D	DO9698	COAD	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.2222
p.S1114F	TCGA-GF-A6C9	SKCM	TCGA	PESTT	DEG_SPOP_SBC_1	1104:1108	Mutation rewiring degron network	0.1667
p.S1114F	DO51254	SKCM	ICGC	PESTT	DEG_SPOP_SBC_1	1104:1108	Mutation rewiring degron network	0.1667
p.G299D	TCGA-GM-A2DA	BRCA	TCGA	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0556
p.G299D	DO4569	BRCA	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0556
p.G299D	SIDM00282	Colorectal Carcinoma	GDSC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0556
p.G299D	ACH-000998	Colon/Colorectal Cancer	CCLE	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0556
p.G299D	CW-2	large intestine	COSMIC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation rewiring degron network	0.0556
p.A1158P	TCGA-KU-A66S	HNSC	TCGA	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.A1158P	DO44456	HNSC	ICGC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.P1370S	TCGA-W3-A824	SKCM	TCGA	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1944
p.P1370S	DO51271	SKCM	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1944
p.N1381D	DO218796	BRCA	ICGC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.2778
p.S1505L	DO225215	BRCA	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	DO227836	BRCA	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00672	Hepatocellular Carcinoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00656	Burkitt's Lymphoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00346	Chronic Myelogenous Leukemia	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00493	Other Solid Cancers	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00844	Burkitt's Lymphoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S1505L	SIDM00641	Burkitt's Lymphoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.2778
p.S379C	DO222645	ESCA	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation altering degron motif	0.643
p.S939R	DO233760	GACA	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1111
p.K1166Q	DO233728	GACA	ICGC	PPQY	ITCH	1154:1157	Mutation substituting flanking lysine	0.1944
p.G1506D	DO229345	LAML	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.3056
p.G1506D	SIDM01749	Osteosarcoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.3056
p.T1521I	DO228945	LICA	ICGC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.0556
p.Q369K	DO229026	LICA	ICGC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0833
p.R312Q	DO52387	LUSC	ICGC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.6218
p.P921S	DO220877	MELA	ICGC	VPTSS	DEG_SPOP_SBC_1	927:931	Mutation rewiring degron network	0.1667
p.S1086F	DO222710	MELA	ICGC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation rewiring degron network	0.2778
p.Q1160P	SIDM02039	Colorectal Carcinoma	GDSC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.25
p.S1165C	SIDM00334	Endometrial Carcinoma	GDSC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.S1165C	SIDM00345	Non-Small Cell Lung Carcinoma	GDSC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.S1165C	ACH-000627	Lung Cancer	CCLE	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.S1165C	ACH-000879	Endometrial/Uterine Cancer	CCLE	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.S1165C	LCLC-103H	lung	COSMIC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.S1165C	MFE-296	endometrium	COSMIC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.1111
p.T1159S	SIDM00336	Melanoma	GDSC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.2778
p.T1159S	ACH-000881	Skin Cancer	CCLE	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.2778
p.T1159S	MEL-JUSO	skin	COSMIC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.2778
p.P1247L	SIDM01175	Other Sarcomas	GDSC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1247L	ACH-002309	Sarcoma	CCLE	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1247L	SW684	soft tissue	COSMIC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1247S	SIDM01175	Other Sarcomas	GDSC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1247S	ACH-002309	Sarcoma	CCLE	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1247S	SW684	soft tissue	COSMIC	KHQVFSD	LIG_APCC_ABBAyCdc20_2	1235:1241	Mutation rewiring degron network	0.1667
p.P1370H	SIDM00654	Small Cell Lung Carcinoma	GDSC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1944
p.P1370H	ACH-000866	Lung Cancer	CCLE	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1944
p.P1370H	NCI-H1048	lung	COSMIC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1944
p.S1368R	SIDM00654	Small Cell Lung Carcinoma	GDSC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1389
p.S1368R	ACH-000866	Lung Cancer	CCLE	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1389
p.S1368R	NCI-H1048	lung	COSMIC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1389
p.T391N	SIDM00716	Squamous Cell Lung Carcinoma	GDSC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0833
p.T391N	ACH-000481	Lung Cancer	CCLE	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0833
p.T391N	NCI-H2170	lung	COSMIC	ASTSS	DEG_SPOP_SBC_1	378:382	Mutation rewiring degron network	0.0833
p.L1153M	SIDM00537	Colorectal Carcinoma	GDSC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.L1153M	ACH-000982	Colon/Colorectal Cancer	CCLE	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.L1153M	ACH-001345	Colon/Colorectal Cancer	CCLE	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.L1153M	GP5d	large intestine	COSMIC	PPQY	ITCH	1154:1157	Mutation rewiring degron network	0.3056
p.Q1499H	SIDM00534	Colorectal Carcinoma	GDSC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.1111
p.Q1499H	ACH-000986	Colon/Colorectal Cancer	CCLE	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.1111
p.Q1499H	HT-115	large intestine	COSMIC	PISSS	DEG_SPOP_SBC_1	1507:1511	Mutation rewiring degron network	0.1111
p.D615Y	SIDM00118	Colorectal Carcinoma	GDSC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.0833
p.D615Y	ACH-001081	Colon/Colorectal Cancer	CCLE	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.0833
p.D615Y	HCC2998	large intestine	COSMIC	PETTT	DEG_SPOP_SBC_1	602:606	Mutation rewiring degron network	0.0833
p.E1095D	SIDM01228	Melanoma	GDSC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation altering degron motif	0.6758
p.E1095D	ACH-001024	Skin Cancer	CCLE	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation altering degron motif	0.6758
p.E1095D	CHL-1	skin	COSMIC	PWVTPKFE	DEG_SCF_FBW7_2	1088:1095	Mutation altering degron motif	0.6758
p.R1386P	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1389
p.R1386P	ACH-000797	Non-Cancerous	CCLE	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation rewiring degron network	0.1389
p.R309C	SIDM01424	B-Lymphoblastic Leukemia	GDSC	RRRRLSIIP	DEG_APCC_DBOX_1	309:317	Mutation altering degron motif	0.719
p.S1379Y	SIDM01588	Endometrial Carcinoma	GDSC	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.712
p.S1379Y	ACH-000993	Endometrial/Uterine Cancer	CCLE	VHSSS	DEG_SPOP_SBC_1	1375:1379	Mutation altering degron motif	0.712
p.K487N	SIDM01588	Endometrial Carcinoma	GDSC	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation substituting flanking lysine	0.25
p.K487N	ACH-000993	Endometrial/Uterine Cancer	CCLE	ADSSS	DEG_SPOP_SBC_1	494:498	Mutation substituting flanking lysine	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

KIAA1210

UniProt ID: Q9ULL0

Entrez ID: 57481

Protein name: Acrosomal protein KIAA1210

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for KIAA1210 in