KinaseMD: Kinase mutations and drug responses

• All kinase in Jak
• All substructure loci
• Gatekeeper loci
• G-loop loci
• A-loop loci
• αC-helix loci

Uniprot ID	Gene symbol	Gatekeeper location	G loop location	A loop location	αC-Helix location
P23458	JAK1	[N/A]	[N/A]	590...597, 881...887	629...644, 919...930
O60674	JAK2	929	698...717, 993...1019	552...559, 855...861	569...571, 889...903
P52333	JAK3	902	966...992	828...834	862...877
P29597	TYK2	978	1040...1066	596...603, 903...909	649...663, 938...953