| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2JT62 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000068583 |
| Ensembl nucleotide ID | ENSRNOG00000019977 |
| Gene name | Receptor-type tyrosine-protein phosphatase F |
| Gene symbol | Ptprf |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAPEPAPGRR MVPLVPALVM LGLMAGAHGD SKPVFVKVPE DQIGLSGGVA SFVCQATGEP 60 KPRITWMKKG KKVSSQRFEV IEFDDGAGSV LRIQPLRVQR DEAIYECTAT NSLGEINTSA 120 KLSVLEEDQL PSGFPTIDMG PQLKVVEKAR TATMLCAAGG NPDPEISWFK DFLPVDPASS 180 NGRIKQLRSG GSPIRGALQI ESSEESDQGK YECVATNSAG TRYSAPANLY VRVRRVAPRF 240 SIPPSSQEVM PGGNVNLTCV AVGAPMPYVK WMMGAEELTK EDEMPVGRNV LELSNVMRSA 300 NYTCVAISSL GMIEATAQVT VKALPKPPID LVVTETTATS VTLTWDSGNT EPVSFYGIQY 360 RAAGTDGPFQ EVDGVASTRY SIGGLSPFSE YAFRVLAVNS IGRGPPSEAV RARTGEQAPS 420 SPPRRVQARM LSASTMLVQW EPPEEPNGLV RGYRVYYTPD SRRPLSAWHK HNTDAGLLTT 480 VGSLLPGITY SLRVLAFTAV GDGPPSPTIQ VKTQQGVPAQ PADFQAKAES DTRIQLSWLL 540 PPQERIIKYE LVYWAAEDEG QQHKVTFDPT SSYTLEDLKP DTLYHFQLAA RSDLGVGVFT 600 PTVEARTAQS TPSAPPQKVT CVSTGSTTVR VSWVPPPADS RNGIITQYSV AYEAVDGEDR 660 KRHVVDGISR EHSSWDLLGL EKWTEYRVWV RAHTDVGPGP ESSPVLVRTD EDVPSGPPRK 720 VEVEPLNSTA VHVSWKLPVP NKQHGQIRGY QVTYVRLENG EPRGQPIIQD VMLAEAQETT 780 ISGLTPETTY SITVAAYTTK GDGARSKPKV VTTTGAVPGR PTMMVSTTAM HTALLQWHPP 840 KELPGELLGY RLQYRRADEA RPNTIDFGKD DQHFTVTGLH KGATYIFRLA AKNRAGPGEE 900 FEKEITTPED APSGFPQNLR VTGLTTSTTE LAWDPPVLAE RNGRITNYTV VYRDINSQHE 960 LQNVTGDVHL TLLGLKPDTT YDIKVRAHTS KGAGPLSPSI QSQTMPMEQV FAKNFRVAAA 1020 MKTSVLLSWE VPDSYKSAVP FKILYNGQSV EVDGHSMRKL IADLQPNTEY SFVLMNRGSS 1080 AGGLQHLVSI RTAPDLLPQK PLPASAFIED GRFSLSMPQV QDPSLVRWFY IVVVPIDRVG 1140 GNLLAPRWST PEELELDELL EAIEQGEEKQ RRRRRQAERL KPYVAAQVDE LPETFTLGDK 1200 KNYRGFYNRP LSPDLSYQCF VLASLKEPMD QKRYASSPYS DEIVVQVTPA QQQEEPEMLW 1260 VTGPVLAVIL IILIVIAILL FKRKRTHSPS SKDEQSIGLK DSLLAHSSDP VEMRRLNYQT 1320 PGMRDHPPIP ITDLADNIER LKANDGLKFS QEYESIDPGQ QFTWENSNSE VNKPKNRYAN 1380 VIAYDHSRVL LTSIDGVPGS DYINANYIDG YRKQNAYIAT QGPLPETMGD FWRMVWEQRT 1440 ATVVMMTRLE EKSRVKCDQY WPARGTETYG LIQVTLVDTV ELATYTMRTF ALHKSGSSEK 1500 RELRQFQFMA WPDHGVPEYP TPILAFLRRV KACNPLDAGP MVVHCSAGVG RTGCFIVIDA 1560 MLERMKHEKT VDIYGHVTCM RSQRNYMVQT EDQYVFIHEA LLEAAMCGHT EVLARNLYAH 1620 IQKLGQVPPG ESVTAMELEF KLLANSKAHT SRFISANLPC NKFKNRLVNI MPYELTRVCL 1680 QPIRGVEGSD YINASFLDGY RQQKAYIATQ GPLAESTEDF WRMLWEHNST IIVMLTKLRE 1740 MGREKCHQYW PAERSARYQY FVVDPMAEYN MPQYILREFK VTDARDGQSR TIRQFQFTDW 1800 PEQGVPKTGE GFIDFIGQVH KTKEQFGQDG PITVHCSAGV GRTGVFITLS IVLERMRYEG 1860 VVDMFQTVKT LRTQRPAMVQ TEDQYQLCYR AALEYLGSFD HYAT 1904 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTPRF | 512072 | A7MBJ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PTPRF | A0A452EN77 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PTPRF | 5792 | P10586 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ptprf | 19268 | A2A8L5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PTPRF | 456828 | K7D8P0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A480JVC3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Ptprf | A0A0G2JT62 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0043005 | neuron projection |
| GO:0043025 | neuronal cell body |
| GO:0050839 | cell adhesion molecule binding |
| GO:0035373 | chondroitin sulfate proteoglycan binding |
| GO:0004725 | protein tyrosine phosphatase activity |
| GO:0044877 | protein-containing complex binding |
| GO:0016477 | cell migration |
| GO:1900121 | negative regulation of receptor binding |
| GO:0031102 | neuron projection regeneration |
| GO:0048679 | regulation of axon regeneration |
| GO:0099560 | synaptic membrane adhesion |
| InterPro ID | InterPro Term |
|---|---|
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR013098 | Ig_I-set |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR029021 | Prot-tyrosine_phosphatase-like |
| IPR000242 | PTPase_domain |
| IPR016130 | Tyr_Pase_AS |
| IPR003595 | Tyr_Pase_cat |
| IPR000387 | TYR_PHOSPHATASE_dom |