Gene:

Basic information

Tag Content
Uniprot ID A0A480JVC3
Entrez ID
Genbank protein ID HDA53273.1
Genbank nucleotide ID
Ensembl protein ID
Ensembl nucleotide ID
Gene name Receptor-type tyrosine-protein phosphatase F isoform X14
Gene symbol
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAPKPAPGRT MMPLVPALVV LGLVAGAHGD SKPVFIKVPE DQTGLSGGVA SFVCQATGEP 60
KPRITWMKKG KKVSSQRFEV IEFDDGAGSV LRIQPLRVQR DEAIYECTAT NSLGEINTSA 120
KLSVLEEEQL PPGFPSIDMG PQLKVVEKAR TATMLCAAGG NPDPEISWFK DFLPVDPATS 180
NGRIKQLRSG ALQIESSEES DQGKYECVAT NSAGTRYSAP ANLYVRVRRV APRFSIPPSS 240
QEVMPGGSVN LTCVAVGAPM PYVKWMVGAE ELTKEDEMPV GRNVLELSNV VRSANYTCVA 300
ISSLGMIEAT AQVTVKALPK PPIDLVVTET TATSVTLTWD SGNSEPVSYY GIQYRPAGTE 360
GPFQEVDGVA TTRYSIGGLS PFSEYAFRVL AVNSIGRGPP SEAVRARTGE QAPSSPPRRV 420
QARMLSASTM LVQWEPPEEP NGLVRGYRVY YTPDSRRPLS AWHKHNTDAG LLTTVGSLLP 480
GITYSLRVLA FTAVGDGPPS PTIQVKTQQG VPAQPADFQA EADSDTRIRL SWLLPPQERV 540
IKYELVYWAA EDEGQQHKVT FDPTSSYTLE DLKPDTLYRF QLAARSEMGV GVFTPTVEAR 600
TAQSTPSAPP QKVTCVSVGS TTVRVSWVPP PADSRNGVIT QYSVAYEAVD GEDRERHVVG 660
GIGREHSSWD LVGLEKWTEY RVWVRAHTDV GPGPESSPVL VRTDEDVPSG PPRKVEVDPL 720
NSTAVRVSWK LPVPSKQHGQ IRGYQVTYVR LENGEPRGPP VIQDVMLAEA QETTISGLTP 780
ETTYSITVAA YTTKGDGARS KPKIVTTTGA VFAKNFRVAA AMKTSVLLSW EVPDSYKSAV 840
PFRILYNGQS VEVDGHSMQK LIANLQPNTE YSFVLMNRGS SAGGLQHLVS IRTAPDLLPH 900
KPLPASAFIE DGRFTLSMPH VQDPSLIRWF YIMVVPIDRV GGSMLAPRWS TPEELELDEL 960
LEAIEQGGGE RRRRRRRQTE RLKPYVAAQV DVLPETFTLG DKKSYRGFYN RPLSPDLSYQ 1020
CFVLASLKEP VDQKRYAASP YSDEIVVQVT PAQQQEEPEM LWVTGPVLAV ILIILIVIAI 1080
LLFKRKRTQS PSSKDEQSIG LKDSLLAHSS DPVEMRRLNY QTPGMRDHPP IPVTDLADNI 1140
ERLKANDGLK FSQEYESIDP GQQFTWENSN LEVNKPKNRY ANVIAYDHSR VILTSIDGVP 1200
GSDYINANYI DGYRKQNAYI ATQGPLPETM GDFWRMVWEQ RTATVVMMTR LEEKSRVKCD 1260
QYWPARGTET YGLVQVTLLD TVELATYTVR TFALHKSGSS EKRELRQFQF MAWPDHGVPE 1320
YPTPILAFLR RVKACNPLDA GPMVVHCSAG VGRTGCFIVI DAMLERMKHE KTVDIYGHVT 1380
CMRAQRNYMV QTEDQYVFIH EALLEAATCG HTEVPARSLY AHIQKLGQVP PGESVTAMEL 1440
EFKLLASSKA HTSRFISANL PCNKFKNRLV NIMPYELTRV CLQPIRGVEG SDYINASFLD 1500
GYRQQKAYIA TQGPLAESTE DFWRMLWEHN STIVVMLTRL REMGREKCHQ YWPAERSARY 1560
QYFVVDPMAE YNMPQYILRE FKVTDARDGQ SRTIRQFQFT DWPEQGVPKT GEGFIDFIGQ 1620
VHKTKEQFGQ DGPITVHCSA GVGRTGVFIT LSIVLERMRY EGVVDMFQTV KTLRTQRPAM 1680
VQTEDQYQLC YRAALEYLGS FDHYAT 1706

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPTPRF512072A7MBJ4Bos taurusPredictionMore>>
1:1 orthologPTPRFA0A452EN77Capra hircusPredictionMore>>
1:1 orthologPTPRF5792P10586Homo sapiensPredictionMore>>
1:1 orthologPtprf19268A2A8L5CPOMus musculusPublicationMore>>
1:1 orthologPTPRF456828K7D8P0Pan troglodytesPredictionMore>>
1:1 orthologA0A480JVC3Sus scrofaPredictionMore>>
1:1 orthologPtprfA0A0G2JT62Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0004725 protein tyrosine phosphatase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0378 Hydrolase
KW-0472 Membrane
KW-0904 Protein phosphatase
KW-0675 Receptor
KW-0677 Repeat
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR000387 TYR_PHOSPHATASE_dom

PROSITE

PROSITE ID PROSITE Term
PS50853 FN3
PS50835 IG_LIKE
PS00383 TYR_PHOSPHATASE_1
PS50056 TYR_PHOSPHATASE_2
PS50055 TYR_PHOSPHATASE_PTP

Pfam

Pfam ID Pfam Term
PF00041 fn3
PF07679 I-set
PF00102 Y_phosphatase