| Tag | Content |
|---|---|
| Uniprot ID | K7D8P0; A0A2J8LZH7; |
| Entrez ID | 456828 |
| Genbank protein ID | JAA16896.1; JAA31404.1; JAA42543.1; JAA10247.1; |
| Genbank nucleotide ID | XM_016960838.1 |
| Ensembl protein ID | ENSPTRP00000078056 |
| Ensembl nucleotide ID | ENSPTRG00000000641 |
| Gene name | Protein tyrosine phosphatase receptor type F |
| Gene symbol | PTPRF |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAPEPAPGRT MVPLVPALVM LGLVAGAHGD SKPVFIKVPE DQTGLSGGVA SFVCQATGEP 60 KPRITWMKKG KKVSSQRFEV IEFDDGAGSV LRIQPLRVQR DEAIYECTAT NSLGEINTSA 120 KLSVLEEEQL PPGFPSIDMG PQLKVVEKAR TATMLCAAGG NPDPEISWFK DFLPVDPAAS 180 NGRIKQLRSG ALQIESSEES DQGKYECVAT NSAGTRYSAP ANLYVRVRRV APRFSIPPSS 240 QEVMPGGSVN LTCVAVGAPM PYVKWMMGAE ELTKEDEMPV GRNVLELSNV VRSANYTCVA 300 ISSLGMIEAT AQVTVKALPK PPIDLVVTET TATSVTLTWD SGNSEPVTYY GIQYRAAGTE 360 GPFQEVDGVA TTRYSIGGLS PFSEYAFRVL AVNSIGRGPP SEAVRARTGE QAPSSPPRRV 420 QARMLSASTM LVQWEPPEEP NGLVRGYRVY YTPDSRRPPN AWHKHNTDAG LLTTVGSLLP 480 GITYSLRVLA FTAVGDGPPS PTIQVKTQQG VPAQPADFQA EVESDTRIQL SWLLPPQERI 540 IMYELVYWAA EDEDQQHKVT FDPTSSYTLE DLKPDTLYRF QLAARSDMGV GVFTPTIEAR 600 TAQSTPSAPP QKVMCVSMGS TTVRVSWVPP PADSRNGVIT QYSVAYEAVD GEDRGRHVVD 660 GISREHSSWD LVGLEKWTEY RVWVRAHTDV GPGPESSPVL VRTDEDVPSG PPRKVEVEPL 720 NSTAVHVYWK LPVPSKQHGQ IRGYQVTYVR LENGEPRGLP IIQDVMLAEA QETTISGLTP 780 ETTYSVTVAA YTTKGDGARS KPKIVTTTGA VPGRPTMMIS TTAMNTALLQ WHPPKELPGE 840 LLGYRLQYCR ADEARPNTID FGKDDQHFTV TGLHKGTTYI FRLAAKNRAG LGEEFEKEIR 900 TPEDLPSGFP QNLRVTGLTT STTELAWDPP VLAERNGRIT SYTVVFRDIN SQQELQNITT 960 DTRFTLTGLK PDTTYDIKVR AWTSKGSGPL SPSIQSRTMP VEQVFAKNFR VAAAMKTSVL 1020 LSWEVPDSYK SAVPFKILYN GQSVEVDGHS MRKLIADLQP NTEYSFVLMN RGSSAGGLQH 1080 LVSIRTAPDL LPHKPLPASA YIEDGRFDLS MPHVQDPSLV RWFYIVVVPI DRVGGSMLTP 1140 RWSTPEELEL DELLEAIEQG GEEQRRRRRQ AERLKPYVAA QLDVLPETFT LGDKKNYRGF 1200 YNRPLSPDLS YQCFVLASLK EPMDQKRYAS SPYSDEIVVQ VTPAQQQEEP EMLWVTGPVL 1260 AVILIILIVI AILLFKRKRT HSPSSKDEQS IGLKDSLLAH SSDPVEMRRL NYQTPGMRDH 1320 PPIPITDLAD NIERLKANDG LKFSQEYESI DPGQQFTWEN SNLEVNKPKN RYANVIAYDH 1380 SRVILTSIDG VPGSDYINAN YIDGYRKQNA YIATQGPLPE TMGDFWRMVW EQRTATVVMM 1440 TRLEEKSRVK CDQYWPARGT ETYGLIQVTL LDTVELATYT VRTFALHKSG SSEKRELRQF 1500 QFMAWPDHGV PEYPTPILAF LRRVKACNPL DAGPMVVHCS AGVGRTGCFI VIDAMLERMK 1560 HEKTVDIYGH VTCMRSQRNY MVQTEDQYVF IHEALLEAAT CGHTEVPARN LYAHIQKLGQ 1620 VPPGESVTAM ELEFKLLASS KAHTSRFISA NLPCNKFKNR LVNIMPYELT RVCLQPIRGV 1680 EGSDYINASF LDGYRQQKAY IATQGPLAES TEDFWRMLWE HNSTIIVMLT KLREMGREKC 1740 HQYWPAERSA RYQYFVVDPM AEYNMPQYIL REFKVTDARD GQSRTIRQFQ FTDWPEQGVP 1800 KTGEGFIDFI GQVHKTKEQF GQDGPITVHC SAGVGRTGVF ITLSIVLERM RYEGVVDMFQ 1860 TVKTLRTQRP AMVQTEDQYQ LCYRAALEYL GSFDHYAT 1898 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTPRF | 512072 | A7MBJ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PTPRF | A0A452EN77 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PTPRF | 5792 | P10586 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ptprf | 19268 | A2A8L5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PTPRF | 456828 | K7D8P0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A480JVC3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Ptprf | A0A0G2JT62 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0004725 | protein tyrosine phosphatase activity |
| InterPro ID | InterPro Term |
|---|---|
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR013098 | Ig_I-set |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR029021 | Prot-tyrosine_phosphatase-like |
| IPR000242 | PTPase_domain |
| IPR016130 | Tyr_Pase_AS |
| IPR003595 | Tyr_Pase_cat |
| IPR000387 | TYR_PHOSPHATASE_dom |