| Tag | Content |
|---|---|
| Uniprot ID | A0A452EN77 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000013563 |
| Ensembl nucleotide ID | ENSCHIG00000014877 |
| Gene name | Uncharacterized protein |
| Gene symbol | PTPRF |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTPEPAPGRT MVPLVPALVM LGLVAGAHGD SKPVFVKVPE DQTGLSGGVA SFVCQATGEP 60 KPRITWMKKG KKVSSQRFEV IEFDDGAGSV LRIQPLRVQR DEAIYECTAT NSLGEINTSA 120 KLSVLEAEQL PDGFPSIDMG PQLKVVEKAR TATMLCAAGG DPDPEISWFK DFLPVDPAAS 180 NGRIKQLRSG ALQIESSEES DQGKYECVAT NSAGTRYSAP ANLYVRVRRV APRFSIPPSS 240 QEVMPGGSVN LTCVAVGAPM PYVKWMMGAE ELTKEDEMPV GRNVLELSNV VRSANYTCVA 300 ISSLGMIEAT AQVTVKALPK PPVDLVVTET TATSVTLTWD SGNSEPVSYY GIQYRPAGAE 360 GPFQEVDGVA TTRYSIGGLS PFSEYAFRVL AVNSIGRGPP SEAVRARTGE QAPSSPPRRV 420 QARMLSASTM LVQWEPPEEP NGLVRGYRVY YTPDSRRPLS AWHKHNTDAG LLTTVGSLLP 480 GITYSLRVLA FTAVGDGPPS PTIQVKTQQG VPAQPADFQA EADSDTRIQL SWLLPPQERI 540 VKYELVYWAA EDEGQQHKVT FDPTSSYTVE DLKPDTLYRF QLAARSELGV GVFTPTVEAR 600 TAQSTPSAPP QKVTCVSVGS TTVRVSWVPP PADSRNGVIT QYSVAYEAVD GEDRGRHVVD 660 GIGREHSSWD LVGLEKWTEY RVWVRAHTDV GPGPESSPVL VRTDEDVPSG PPRKVEVEPL 720 NSTAVRVSWK LPVPSKQHGQ IRGYQVTYVR LENGEPRGAP IIQDVMLAEA QVCPREVETT 780 ISGLTPETTY SITVAAYTTK GDGARSKPKI VTTTGAVPGR PTMMVSTTAM NTALLQWHPP 840 KELPGELLGY RLQYRRADEA RPNTIDFGKD DQHFTVTGLH KGATYIFRLA AKNRAGLGEE 900 FEKEITTPED VPSGFPQNLR VIGLTTSTTE LIWDPPVLAE RNGRITNYTV VYRDINSQQE 960 LQNVTADTHL TLSGLKPDTT YDIKVRARTS KGAGPLSPSI QSRTMPVEQV FAKNFRVEAA 1020 MKTSVLLSWE VPDSYKSAVP FRILYNGQSV EVDGHSMRKL IADLQPNTEY SFVLMNRGSS 1080 AGGLQHLVSI RTAPDLLPHK PLPASAYVED GRFTLTMPHV QDPSLVRWFY IMVVPIDRMA 1140 GSMLAPQWST PEELELDELL EAIEQGGRER RRRQTERLKP YVAAQVDVLP ETFTLGDKKN 1200 YQGFYNRPLS PDLSYQCFVL ASLKEPVDQK RYACSPYSDE IVVQVTPAQQ QEEPELLWVT 1260 GPVLAVILIV LIVIAILLFK RKRTHSPSSK DEQSIGLKDS LLAHSSDPVE MRRLNYQTPG 1320 MRDHPPIPIT DLADNIERLK ANDGLKFSQE YESIDPGQQF TWENSNLEVN KPKNRYANVI 1380 AYDHSRVILT SIDGVPGSDY INANYIDGYR KQNAYIATQG PLPETMGDFW RMVWEQRTAT 1440 VVMMTRLEEK SRVKCDQYWP ARGTETYGLI QVTLLDTVEL ATYTVRTFAL YKSGSSEKRE 1500 LRQFQFMAWP DHGVPEYPTP ILAFLRRVKA CNPLDAGPMV VHCSAGVGRT GCFIVIDAML 1560 ERMKHEKTVD VYGHVTCMRA QRNYMVQTED QYVFIHEALL EAAACGHTEV PARSLHAHIQ 1620 KLGQVPPGES VTAMELEFKL LANSKAHTSR FISANLPCNK FKNRLVNIMP YELTRVCLQP 1680 IRGVEGSDYI NASFLDGYRS QKAYIATQGP LAESTEDFWR MLWEHNSTII VMLTRLREMG 1740 REKCHQYWPA ERSARYQYFV VDPMAEYNMP QYILREFKVT DARDGQSRTI RQFQFTDWPE 1800 QGVPKTGEGF IDFIGQVHKT KEQFGQDGPI TVHCSAGVGR TGVFITLSIV LERMRYEGVV 1860 DMFQTVKTLR TQRPAMVQTE DQYQLCYRAA LEYLGSFDHY AT 1902 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PTPRF | 512072 | A7MBJ4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PTPRF | A0A452EN77 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PTPRF | 5792 | P10586 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ptprf | 19268 | A2A8L5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PTPRF | 456828 | K7D8P0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | A0A480JVC3 | Sus scrofa | Prediction | More>> | ||||
| 1:1 ortholog | Ptprf | A0A0G2JT62 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0043005 | neuron projection |
| GO:0043025 | neuronal cell body |
| GO:0050839 | cell adhesion molecule binding |
| GO:0035373 | chondroitin sulfate proteoglycan binding |
| GO:0004725 | protein tyrosine phosphatase activity |
| GO:0044877 | protein-containing complex binding |
| GO:0016477 | cell migration |
| GO:1900121 | negative regulation of receptor binding |
| GO:0031102 | neuron projection regeneration |
| GO:0048679 | regulation of axon regeneration |
| GO:0099560 | synaptic membrane adhesion |
| InterPro ID | InterPro Term |
|---|---|
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR007110 | Ig-like_dom |
| IPR036179 | Ig-like_dom_sf |
| IPR013783 | Ig-like_fold |
| IPR013098 | Ig_I-set |
| IPR003599 | Ig_sub |
| IPR003598 | Ig_sub2 |
| IPR029021 | Prot-tyrosine_phosphatase-like |
| IPR000242 | PTPase_domain |
| IPR016130 | Tyr_Pase_AS |
| IPR003595 | Tyr_Pase_cat |
| IPR000387 | TYR_PHOSPHATASE_dom |