Gene:

Basic information

Tag Content
Uniprot ID A0A0G2JU83
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000069002
Ensembl nucleotide ID ENSRNOG00000052574
Gene name Tudor domain-containing protein
Gene symbol
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPSRKFAEGE VVRGRWPGSS LYYEVEILSH DNKSQVYTVK YKDGTELELK ESDIKPLKSF 60
KQRKSGSTSS SPSRRRSSRS RSRSRSRSPG RAPKGSRRSV SASYQADAKE KEMRREILQV 120
KLTPLVLKPF ANSVSVYNGE PEHMEKSATP PKNKQDLLYI STLSAYVLSK QSQTHRRRAI 180
RSPLQIRWTN FGSENPVPLV TLDVPEPVVR DHELGTEPSA LLIMLGLPAC VFLLLLQCAQ 240
KDPGLLQFPP PLPALRELWE ARVCGVYLLW FFLQALFSLL PVGKVRSGNP AHEMGSLTFR 300
FKGLYAFILT SAAVGTAVFW DIELYYLYTH FLQFALAAIV FSVVLSVYLY ARSLKVPRDE 360
LSPASSGNAV YDFFIGRELN PRIGAFDLKF FCELRPGLIG WVVINLVMLL AEMKVQERSA 420
PSLAMTLVNS FQLLYVVDAL WFEEALLTTM DIIHDGFGFM LAFGDLVWVP FTYSLQAFYL 480
VNHPQDLSWP LASVIIALKL CGYVIFRCAN SQKNAFRKNP TDPKLAHLKT IPTSTGKSLL 540
VSGWWGFVRH PNYLGDLIMA LAWSLPCGFN HILPYFYVIY FTALLIHREA RDEHQCRRKY 600
GLAWEKYCQR VPYRIFPYIY

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologLBR509348A6QQV8Bos taurusPredictionMore>>
1:1 orthologLBR490391E2QV27Canis lupus familiarisPredictionMore>>
1:1 orthologLBR100056997A0A3Q2GWX9Equus caballusPredictionMore>>
1:1 orthologLBR3930Q14739Homo sapiensPredictionMore>>
1:1 orthologLbr98386Q3U9G9CPOMus musculusPublicationMore>>
1:1 orthologLBR457776H2Q178Pan troglodytesPredictionMore>>
1:1 orthologLBRM3VH35Sus scrofaPredictionMore>>
1:1 orthologLBR100345014G1SCZ4Oryctolagus cuniculusPredictionMore>>
1:1 orthologA0A0G2JU83Rattus norvegicusPredictionMore>>
1:1 orthologlbrQ5RJ97Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016021 integral component of membrane
GO:0005637 nuclear inner membrane
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0016126 sterol biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR001171 Ergosterol_biosynth_ERG4_ERG24
IPR019023 Lamin-B_rcpt_of_tudor
IPR018083 Sterol_reductase_CS
IPR002999 Tudor

PROSITE

PROSITE ID PROSITE Term
PS01017 STEROL_REDUCT_1
PS01018 STEROL_REDUCT_2

Pfam

Pfam ID Pfam Term
PF01222 ERG4_ERG24
PF09465 LBR_tudor