| Tag | Content |
|---|---|
| Uniprot ID | M3VH35 |
| Entrez ID | |
| Genbank protein ID | HDA25514.1; HDA67284.1; HDA30392.1; JAA74058.1; HDB49043.1; |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000046854 |
| Ensembl nucleotide ID | ENSSSCG00000032397 |
| Gene name | Lamin-B receptor |
| Gene symbol | LBR |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPTRRFADGE VVRGRWPGSS LYYEVEILSH DSKSQLYTVK YKDGTELELK ESDIKPLTSF 60 RQRKSGSASS SPSRRRGSRS RSRSRSPGRP PRSSRRSASA SHQADRKEVR KEILEVKLTP 120 LVLKPFGNSI NRYNGEPEHR EKNDLPHKTT QVHTGSFSLQ EKFHLPQESS YLSTQYSLRP 180 RREEIKLKEI DAQEEKIVTE GPTSLRTFEV TTKQLKEVEF GGVPGVLTIM LGLPAFLFLL 240 LLMCKQKEPS LLNFPPPLPA LSDLWDARVF GLYLVWFFLQ ALFYLLPIGK VVEGTPLADG 300 RRLKYRLNGF YAFILTSGLV GASLLWDVEL YYVYNHFLQF ALAATVWAVV LSVYLCARAL 360 KAPRNDLSPA SSGNAIYDFF IGRELNPRIG TFDLKYFCEL RPGLIGWVVI NLVMLLAEMK 420 VQNRAFPSLA MILVNSFQLL YVVDALWNEE ALLTTMDIIH DGFGFMLAFG DLVWVPFIYS 480 FQAFYLVAHP NELSWPAASL IVALKLCGFI IFRCANSQKN AFRKNPNDPK LAHLKTIHTS 540 TGKNLLVSGW WGFVRHPNYL GDLIMALAWS LPCGFSHILP YFYVIYFTAL LVHREARDEH 600 HCKRKYGLAW EKYCQRVPYR IFPHIY 626 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LBR | 509348 | A6QQV8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 490391 | E2QV27 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | LBR | 100056997 | A0A3Q2GWX9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 3930 | Q14739 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lbr | 98386 | Q3U9G9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LBR | 457776 | H2Q178 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | LBR | M3VH35 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | LBR | 100345014 | G1SCZ4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | A0A0G2JU83 | Rattus norvegicus | Prediction | More>> | ||||
| 1:1 ortholog | lbr | Q5RJ97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0070087 | chromo shadow domain binding |
| GO:0050613 | delta14-sterol reductase activity |
| GO:0070402 | NADPH binding |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0030223 | neutrophil differentiation |
| GO:0016126 | sterol biosynthetic process |