| Tag | Content |
|---|---|
| Uniprot ID | E2QV27 |
| Entrez ID | 490391 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_547512.5 |
| Ensembl protein ID | ENSCAFP00000023948 |
| Ensembl nucleotide ID | ENSCAFG00000016244 |
| Gene name | Lamin B receptor |
| Gene symbol | LBR |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPSRKFADGE VVRGRWPGSS LYYEVEILSH DSHSQLYTVQ YKDGTELELK ENDIKPLTSF 60 RQRKSGSTSS SPSRRRGSRS RSRSRSPGRP PRSSRRSASA SHQADMKEMR KEVLEVKLTP 120 LVLKPFGNSI SRYNGEPEHT ERDGMLHRNA EEKFHLSEEI RSMSTQYSLR PRREEIKLKD 180 IDSKEENIVP TKGSTLLKTS EVLGTQPKSL EFGGVPGVFL IMLGLPTFLF LLLLLCKEKE 240 PSLLNFPPPM PALSELWDTR AFAIYFFWFS LQALFYILPI GKVVEGMPLA DGRRLKYRLN 300 GFYAFLLTCV AVGAALCRGV ELHYVYHHFL PLALAAATFA MALSTYLAVR AAWAPPAALA 360 PASSGNAIYD FFIGRELNPR IGTFDLKYFC ELRPGLIGWV VVNLVMLLAE MKLQHRAAPS 420 LAMILVNSFQ LLYVVDALWN EEALLTTMDI THDGFGFMLA FGDLVWVPFI YSFQAFYLVN 480 HPNEVSWPMA SLIIALKLCG YVIFRCANSQ KNAFRKNPTD PKLAHLKTIH TSTGKNLLVS 540 GWWGFVRHPN YLGDLIMALA WSLPCGFKHV LPYFYVIYFT VLLVHREARD ERHCRKKYGL 600 AWEKYCQRVP YRIFPYVY 618 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LBR | 509348 | A6QQV8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 490391 | E2QV27 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | LBR | 100056997 | A0A3Q2GWX9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 3930 | Q14739 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lbr | 98386 | Q3U9G9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LBR | 457776 | H2Q178 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | LBR | M3VH35 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | LBR | 100345014 | G1SCZ4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | A0A0G2JU83 | Rattus norvegicus | Prediction | More>> | ||||
| 1:1 ortholog | lbr | Q5RJ97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0070087 | chromo shadow domain binding |
| GO:0050613 | delta14-sterol reductase activity |
| GO:0070402 | NADPH binding |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0030223 | neutrophil differentiation |
| GO:0016126 | sterol biosynthetic process |