| Tag | Content |
|---|---|
| Uniprot ID | H2Q178; A0A2J8K9H5; |
| Entrez ID | 457776 |
| Genbank protein ID | JAA31897.1; JAA40962.1; JAA05540.1; JAA16649.1; |
| Genbank nucleotide ID | XM_016939725.1; XM_514234.5; |
| Ensembl protein ID | ENSPTRP00000003438 |
| Ensembl nucleotide ID | ENSPTRG00000002036 |
| Gene name | Lamin B receptor |
| Gene symbol | LBR |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPSRKFADGE VVRGRWPGSS LYYEVEILSH DSTSQLYTVK YKDGTELELK ENDIKPLTSF 60 RQRKGGSTSS SPSRRRGSRS RSRSRSPGRP PKSARRSASA SHQADIKEAR REVEVKLTPL 120 ILKPFGNSIS RYNGEPEHIE RNDAPHKNTQ EKFNLSQESS YIATQYSLRP RKEEVKLKEI 180 DSKEEKYIAK ELAVRTFEVT PIRAKDLEFG GVPGVFLIMF GLPVFLFLLL LMCKQKDPSL 240 LNFPPPLPAL YELWETRVFG VYLLWFLIQV LFYLLPIGKV VEGTPLIDGR RLKYRLNGFY 300 AFILTSAVIG TSLFQGVEFH YVYSHFLQFA LAATVFCVVL SVYLYVRSLK APRNDLSPAS 360 SGNAVYDFFI GRELNPRIGT FDLKYFCELR PGLIGWVVVN LVMLLAEMKI QDRAVPSLAM 420 ILVNSFQLLY VVDALWNEEA LLTTMDIIHD GFGFMLAFGD LVWVPFIYSF QAFYLVSHPN 480 EVSWPMASLI IVLKLCGYVI FRGANSQKNA FRKNPSDPKL AHLKTIHTST GKNLLVSGWW 540 GFVRHPNYLG DLIMALAWSL PCGFNHILPY FYIIYFTMLL VHREARDEYH CKKKYGVAWE 600 KYRQRVPYRI FPYIY 615 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LBR | 509348 | A6QQV8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 490391 | E2QV27 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | LBR | 100056997 | A0A3Q2GWX9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | LBR | 3930 | Q14739 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lbr | 98386 | Q3U9G9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LBR | 457776 | H2Q178 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | LBR | M3VH35 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | LBR | 100345014 | G1SCZ4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | A0A0G2JU83 | Rattus norvegicus | Prediction | More>> | ||||
| 1:1 ortholog | lbr | Q5RJ97 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005789 | endoplasmic reticulum membrane |
| GO:0016021 | integral component of membrane |
| GO:0005637 | nuclear inner membrane |
| GO:0070087 | chromo shadow domain binding |
| GO:0050613 | delta14-sterol reductase activity |
| GO:0070402 | NADPH binding |
| GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors |
| GO:0006695 | cholesterol biosynthetic process |
| GO:0030223 | neutrophil differentiation |
| GO:0016126 | sterol biosynthetic process |