| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2JX92 |
| Entrez ID | 309460 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_008760439.2 |
| Ensembl protein ID | ENSRNOP00000070182 |
| Ensembl nucleotide ID | ENSRNOG00000020353 |
| Gene name | SH3 and PX domains 2A |
| Gene symbol | Sh3pxd2a |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLAYCVQDAT VVDVEKRRNP SKHYVYIINV TWSDSTSQTI YRRYSKFFDL QMQLLDKFPI 60 EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VKRLKPINEY CRALVRLPPH ISQCDEVFRF 120 FEARPEDVNP PKEDYGSSKR KSGADTNAEP MILEQYVVVS NYKKQENSEL SLQAGEVVDV 180 IEKNESGWWF VSTSEEQGWV PATYLEAQNG TRDDSDINTS KTGEVSKRRK AHLRRLDRRW 240 TLGGMVNRQH SREEKYVTVQ PYTSQSKDEI GFEKGVTVEV IRKNLEGWWY IRYLGKEGWA 300 PASYLKKAKD DLPTRKKNLA GPVEIIGSIM EISNLLNKKA SGDKEAPVEG EGSEAPISKK 360 EISLPILCNA SNGSASGIPE RTTSKLAQGS PAVARIAPQR AQISSPNLRT RPPPRRESSL 420 GFQLPKPPEP PSVEVEYYTI AEFQSCISDG ISFRGGQKAE VIDKNSGGWW YVQIGEKEGW 480 APASYIDKRK KPNLSRRTST LTRPKVPPPA PPGKPKETEE NPAGACENQG SPLKLKYEEP 540 EYDIPAFGFD SEPELNEEPT EDRGSGDKHP AQPRRTSPAS SLQRAHFKVG ESSEDVALEE 600 ETIYENEGFR PYTEDTLSAR GSSGDSDSPG NSSLSLAMKN SPKSDSPKSS SLLKLKAEKN 660 AQAELGKNQS NISFSSSVTI GTTSSSSSSS SSLSKNSGDL KPRSASDAGI RDSPKGGTKK 720 DPDVKTGLAS CVRAKPSVRP KPVLNRAESQ SQEKMDISSL RRQLRPTGQL RGGLKGSRSE 780 DSELPPQTAS EGSRRGSADI IPLPATTPPC VPKKEWEGQG TAYVTCSAYQ KVQDSEISFP 840 AGAEVHVLEK VESGWWYVRF GELEGWAPSH YLVPEENQQP DPDSKEPDTV KSTQNEGKSD 900 SLEKIEKRVQ ALNTVNQSKR ATPPIPSKPP GGFGKTSGTV AVKMRNGVRQ VAVRPQSVFV 960 SPPPKDNNLS CALRRNESLT ATDSVRGVRR NSSFSTARSA AAEAKGRLAE RAASQGSESP 1020 LLPTQRNGIP VSPVRPKPIE KSQFIHNNLK DVYVSIADYE GDEETAGFQE GVSMEVLERN 1080 PNGWWYCQIL DEVKPFKGWV PSNYLEKKN 1109 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SH3PXD2A | 486874 | F1PLG9 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SH3PXD2A | A0A452ED30 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | SH3PXD2A | 9644 | Q5TCZ1 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Sh3pxd2a | 14218 | O89032 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | SH3PXD2A | 450714 | A0A2I3RAY9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SH3PXD2A | 100343675 | A0A5F9D2I8 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Sh3pxd2a | 309460 | A0A0G2JX92 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | sh3pxd2aa | 562018 | T1ECT1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0002102 | podosome |
| GO:0035091 | phosphatidylinositol binding |
| GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding |
| GO:0032266 | phosphatidylinositol-3-phosphate binding |
| GO:0005546 | phosphatidylinositol-4,5-bisphosphate binding |
| GO:0070273 | phosphatidylinositol-4-phosphate binding |
| GO:0010314 | phosphatidylinositol-5-phosphate binding |
| GO:0002020 | protease binding |
| GO:0016176 | superoxide-generating NADPH oxidase activator activity |
| GO:0001701 | in utero embryonic development |
| GO:0072675 | osteoclast fusion |
| GO:0072593 | reactive oxygen species metabolic process |
| GO:0006801 | superoxide metabolic process |