Gene: sh3pxd2aa

Basic information

Tag Content
Uniprot ID T1ECT1
Entrez ID 562018
Genbank protein ID
Genbank nucleotide ID NM_001160022.1
Ensembl protein ID ENSDARP00000078892
Ensembl nucleotide ID ENSDARG00000060148
Gene name SH3 and PX domains 2Aa
Gene symbol sh3pxd2aa
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MQILDKFPIE GGQKDPKKRI IPFLPGKILF RRSHVRDVAM KRLRFIDDYC RALVRLPPQI 60
SQSEEVLRFF ETKPDDINPP VEDYGSKRKS GLDSSEPMVL EQYVVVANYE RQENSEISLK 120
AGETVDVIEK SESGWWFVST AEEQGWVPAT YLDSQSGTRD DLDLGTSRSG EVTKRRKAHL 180
KRLDRRWTLG GIVNRQQSRE EKYVSVQAYA SQGKDEIGFE KGVTVEVIQK NLEGWWYIRY 240
QGKEGWAPAS YLKKLKDDLS PRKKTLTGPV EIIGNIMEIS NLLNKKAVSE KDIQTDGEAT 300
TPERHISKSE ISLPMPYAPE AGVAPTVVTA LGMNSGSSAT LQENKSRAEP GSPAIARVAP 360
HRVEIGSPNL RQKPPPRRDA NLAFQLPKPP EAPTVEAEYY TIAEFQSSIS DGISFRGGQK 420
ADVIEKNSGG WWYVQIGDTE GWAPSSYIDK RKKPNLSRRT STLTRPKVPP PAPPVKKQDS 480
EEGPSLGGSA SKAPESPQRV YEEPEYDVPA LGFDSELDCN PPKPKTHNSP KPEPRKFEIK 540
SNPAAAERIA QAGKASPLLK VMTSPLRKRN SLENINKEEV IYENEGFRFS SDDFASGCDS 600
HTPRSLTLGR KPFGSSSGGG KPLRKVSPDL NRSHSLGRAE RHSSKLFSDE SARNPKREPV 660
MRKDVEIRIG QSPLARPKPV VRPKPLLTKS EPQSPERMDI SSIRRHLRPT GSLRQGAIRA 720
MRGEDSETAS VVSSEDSTSS RSTSDLSSVY SKGSRGGESD HESVLFRTTD AYERAQESEL 780
SFPAGVEVEV LEKQESGWWF VRWGSDEGWV PTFYLEPIKH THNVGIQESR DSPLVDLGST 840
NKSNSLEKNE QRVQALNNLN QQNLRSMSNP SPPIPSKPPG GFSKPTAMLN GSSVRMRNGV 900
RQAAVRPQSV FVSPPQPLKE TNIHTGSLRR NESLGAGDHL RSTGGVRRNS SFTAVRPQPV 960
TDVRVRAGTT ITAPAGSSSP LIAQRNGIPI STVRPKPIEK MQLIHNNLRE VYVSIADYRG 1020
DEETMGFSEG TSLEVLEKNP NGWWYCQVLD GLQGRKGWVP SNYLERKK 1068

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSH3PXD2A486874F1PLG9Canis lupus familiarisPredictionMore>>
1:1 orthologSH3PXD2AA0A452ED30Capra hircusPredictionMore>>
1:1 orthologSH3PXD2A9644Q5TCZ1Homo sapiensPredictionMore>>
1:1 orthologSh3pxd2a14218O89032CPOMus musculusPublicationMore>>
1:1 orthologSH3PXD2A450714A0A2I3RAY9Pan troglodytesPredictionMore>>
1:1 orthologSH3PXD2A100343675A0A5F9D2I8Oryctolagus cuniculusPredictionMore>>
1:1 orthologSh3pxd2a309460A0A0G2JX92Rattus norvegicusPredictionMore>>
1:1 orthologsh3pxd2aa562018T1ECT1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0035091 phosphatidylinositol binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0728 SH3 domain

Interpro

InterPro ID InterPro Term
IPR001683 PX_dom
IPR036871 PX_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR034917 SH3PXD2A
IPR035450 SH3PXD2A_SH3_1
IPR035452 SH3PXD2A_SH3_2
IPR035449 SH3PXD2A_SH3_3
IPR035453 SH3PXD2A_SH3_4
IPR035454 SH3PXD2A_SH3_5

PROSITE

PROSITE ID PROSITE Term
PS50195 PX
PS50002 SH3

Pfam

Pfam ID Pfam Term
PF00018 SH3_1
PF07653 SH3_2