Gene: SH3PXD2A

Basic information

Tag Content
Uniprot ID A0A5F9D2I8
Entrez ID 100343675
Genbank protein ID
Genbank nucleotide ID XM_002718708.3
Ensembl protein ID ENSOCUP00000039584
Ensembl nucleotide ID ENSOCUG00000013769
Gene name SH3 and PX domains 2A
Gene symbol SH3PXD2A
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLAYCVQDAT VVDVEKRRNP SKHYVYIINV TWSDSTSQTI YRRYSKFFDL QMQLLDKFPI 60
EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VKRLKPIDEY CRALVRLPPH ISQCDEVFRF 120
FEARPEDVNP PKEDYGSSKR KSVWLSSWTE SPKKDVTGAD SSAEPMILEQ YVVVSNYKKQ 180
ENSELSLQAG EVVDVIEKNE SGWWFVSTSE EQGWVPATYL EAQNGTRDDS DISTSKTGEV 240
SKRRKAHLRR LDRRWTLGGM VNRQHSREEK YVTVQPYTSQ SKDEIGFEKG VTVEVIRKNL 300
EGWWYIRYLG KEGWAPASYL KKAKDDLPAR KKNLAGPVEI IGNIMEISNL LNKKASGDKE 360
TPPADGEGPE APVAKKEISL PILCNASNGS PLGVPERTLS KLAQGSPAVA RIAPQRAQIS 420
SPNLRTRPPP RRESSLGFQL PKPPEPPSVE VEYYTIAEFQ SCISDGISFR GGQKAEVIDK 480
NSGGWWYVQI GDKEGWAPAS YIDKRKKPNL SRRTSTLTRP KVPPPAPPSK PKEAEEGPAA 540
ASESRDSPVK LKYEEPEYDV PAFGCDSEPE LSEEPPEDQG PGDRRPAQPP RPSPSSLQRA 600
RFKVGESSED VALEEETIYE NEGFRPLAED ALSARGSSGD SDSPGGSSLS LARKNSPKSG 660
SPKSSSLLKL KAEKNAQAEL GKNHSSASFA SSITITTTCS SSSSSSSSSL SKNGGELKPR 720
SASDAGIRGA PPVGVRKDVD TRAGLGCARA KPSVRPKPLL NRAESQSQEK MDISTLRRQL 780
RPTGQLRAGL KGSRSEDSEL PPQTASEGSS EASRRGSADT IAPPSPTKKE REGPAASYVT 840
RSAYQKAQDS EISFPAGAEV RVLEKLESGW WYVRFGELEG WAPSHYLVLG ENEQPEPKEL 900
DPGPTKGKSD SLEKTERQVQ ALNTANQSKR ATPPIPCKPP GGFGKSSGPA AVKMRNGVRQ 960
VAVRPQSVFV SPPPKDNNLS CALRRNESLT ATDSLRGVRR NSSFSTARSA AAEAKGRLAE 1020
RAASQGSDSP LLPTQRNGIP VSPVRPKPIE KSQFIHNNLK DVYVSIADYE GDEETAGFQE 1080
GVSMEVLERN PNGWWYCQIL DGVKPFKGWV PSNYLEKKN 1119

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSH3PXD2A486874F1PLG9Canis lupus familiarisPredictionMore>>
1:1 orthologSH3PXD2AA0A452ED30Capra hircusPredictionMore>>
1:1 orthologSH3PXD2A9644Q5TCZ1Homo sapiensPredictionMore>>
1:1 orthologSh3pxd2a14218O89032CPOMus musculusPublicationMore>>
1:1 orthologSH3PXD2A450714A0A2I3RAY9Pan troglodytesPredictionMore>>
1:1 orthologSH3PXD2A100343675A0A5F9D2I8Oryctolagus cuniculusPredictionMore>>
1:1 orthologSh3pxd2a309460A0A0G2JX92Rattus norvegicusPredictionMore>>
1:1 orthologsh3pxd2aa562018T1ECT1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0035091 phosphatidylinositol binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0728 SH3 domain

Interpro

InterPro ID InterPro Term
IPR001683 Phox
IPR036871 PX_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR037961 SH3PXD2_PX
IPR034917 SH3PXD2A
IPR035450 SH3PXD2A_SH3_1
IPR035452 SH3PXD2A_SH3_2
IPR035449 SH3PXD2A_SH3_3
IPR035453 SH3PXD2A_SH3_4
IPR035454 SH3PXD2A_SH3_5

PROSITE

PROSITE ID PROSITE Term
PS50195 PX
PS50002 SH3

Pfam

Pfam ID Pfam Term
PF00787 PX
PF00018 SH3_1