Gene: SH3PXD2A

Basic information

Tag Content
Uniprot ID A0A2I3RAY9; A0A2J8PCS6;
Entrez ID 450714
Genbank protein ID
Genbank nucleotide ID XM_016919277.1
Ensembl protein ID ENSPTRP00000061780
Ensembl nucleotide ID ENSPTRG00000047766
Gene name SH3 and PX domains 2A
Gene symbol SH3PXD2A
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLAYCVQDAT VVDVEKRRNP SKHYVYIINV TWSDSTSQTI YRRYSKFFDL QMQLLDKFPI 60
EGGQKDPKQR IIPFLPGKIL FRRSHIRDVA VKRLKPIDEY CRALVRLPPH ISQCDEVFRF 120
FEARPEDVNP PKEDYGSSKR KSVWLSSWAE SPKKDVTGAD ATAEPMILEQ YVVVSNYKKQ 180
ENSELSLQAG EVVDVIEKNE SGWWFVSTSE EQGWVPATYL EAQNGTRDDS DINTSKTGEE 240
EKYVTVQPYT SQSKDEIGFE KGVTVEVIRK NLEGWWYIRY LGKEGWAPAS YLKKAKDDLP 300
TRKKNLAGPV EIIGNIMEIS NLLNKKASGD KETPPAEGEG HEAPIAKKEI SLPILCNASN 360
GSAVGVPDRT VSRLAQGSPA VARIAPQRAQ ISSPNLRTRP PPRRESSLGF QLPKPPEPPS 420
VEVEYYTIAE FQSCISDGIS FRGGQKAEVI DKNSGGWWYV QIGEKEGWAP ASYIDKRKKP 480
NLSRRTSTLT RPKVPPPAPP SKPKEAEEGP TGASESQDSP RKLKYEEPEY DIPAFGFDSE 540
PELSEEPVED RASGERRPAQ PHRPSPASSL QRARFKVGES SEDVALEEET IYENEGFRPY 600
AEDTLSARGS SGDSDSPGSS SLSLTRKNSP KSGSPKSSSL LKLKAEKNAQ AELGKNHSSA 660
SFSSSITINT TCCSSSSSSS SSLSKTSGDL KPRSASDAGI RGTPKVRAKK DADANAGLTS 720
CARAKPSVRP KPFLNRAESQ SQEKMDISTL RRQLRPTGQL RGGLKGSKSE DSELPPQTAS 780
EAPSEGSRRS SSDLITLPAT TPPCPTKKEW EGPATSYMTC SAYQKVQDSE ISFPAGVEVQ 840
VLEKQESGWW YVRFGELEGW APSHYLVLDE NEQPDPSGKE LDTVPAKGRQ NEGKSDSLEK 900
IERRVQALNT VNQSKKATPP IPSKPPGGFG KTSGTPAVKM RNGVRQVAVR PQSVFVSPPP 960
KDNNLSCALR RNESLTATDG LRGVRRNSSF STARSAAAEA KGRLAERAAS QGSDSPLLPA 1020
QRNSIPVSPV RPKPIEKSQF IHNNLKDVYV SIADYEGDEE TAGFQEGVSM EVLERNPNGW 1080
WYCQILDGVK PFKGWVPSNY LEKKN 1105

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSH3PXD2A486874F1PLG9Canis lupus familiarisPredictionMore>>
1:1 orthologSH3PXD2AA0A452ED30Capra hircusPredictionMore>>
1:1 orthologSH3PXD2A9644Q5TCZ1Homo sapiensPredictionMore>>
1:1 orthologSh3pxd2a14218O89032CPOMus musculusPublicationMore>>
1:1 orthologSH3PXD2A450714A0A2I3RAY9Pan troglodytesPredictionMore>>
1:1 orthologSH3PXD2A100343675A0A5F9D2I8Oryctolagus cuniculusPredictionMore>>
1:1 orthologSh3pxd2a309460A0A0G2JX92Rattus norvegicusPredictionMore>>
1:1 orthologsh3pxd2aa562018T1ECT1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0035091 phosphatidylinositol binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001683 Phox
IPR036871 PX_dom_sf
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
IPR037961 SH3PXD2_PX
IPR034917 SH3PXD2A
IPR035450 SH3PXD2A_SH3_1
IPR035452 SH3PXD2A_SH3_2
IPR035449 SH3PXD2A_SH3_3
IPR035453 SH3PXD2A_SH3_4
IPR035454 SH3PXD2A_SH3_5

PROSITE

PROSITE ID PROSITE Term
PS50195 PX
PS50002 SH3

Pfam

Pfam ID Pfam Term
PF00787 PX
PF00018 SH3_1