| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2KA71 |
| Entrez ID | 308417 |
| Genbank protein ID | EDM08139.1 |
| Genbank nucleotide ID | XM_006228421.2 |
| Ensembl protein ID | ENSRNOP00000075285 |
| Ensembl nucleotide ID | ENSRNOG00000018730 |
| Gene name | Nectin cell adhesion molecule 2 |
| Gene symbol | Nectin2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MARAAVLPPS RLSPTLPLLP LLLLLLQETG AQDVRVRVLP EVRGRLGGTV ELPCHLLPPT 60 TERVSQVTWQ RLDGTVVAAF HPSFGVDFPN SQFNKDRLSF VRAKQEANAD LRDATLAFRG 120 LRVEDEGNYT CEFATFPNGT RRGVTWLRVI AQPENHAEAQ EVTIGPQSVA VARCISTGGR 180 PPARITWISS LGGEARDIQE PGLQAGTVTV ISRYSMVPVG RADGVKVTCR VEHESLEEPE 240 LLPVILSVRY PPEVSISGYD DNWYLGRSEA TLTCEVRSNP EPTGYDWSTT SGVFPASAVA 300 QGSQLLVHSV DRMVNTTFIC TATNAVGTGR AEQVILVRDT PQASRDVGPL VWGAVGGTLL 360 VLLLAGGFLA LILLRGRRRR KSPGGGGSDG DRGSYDPKTQ VFGNGGPVFW RSASPEPMRP 420 DGREEEDEEE EEMKAEEGLM LPPHESPKDD MESHLDGSLI SRRAVYV 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NECTIN2 | 505580 | Q17QC7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 611060 | F1PWL4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | A0A452G7Y9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NECTIN2 | 100065463 | F6YWH3 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 5819 | Q92692 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Nectin2 | 19294 | P32507 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 456118 | K6ZRP3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 100038012 | A2TEQ2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nectin2 | 308417 | A0A0G2KA71 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0043296 | apical junction complex |
| GO:0009986 | cell surface |
| GO:0044291 | cell-cell contact zone |
| GO:0005911 | cell-cell junction |
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005915 | zonula adherens |
| GO:0050839 | cell adhesion molecule binding |
| GO:0042802 | identical protein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0001675 | acrosome assembly |
| GO:0044406 | adhesion of symbiont to host |
| GO:0032990 | cell part morphogenesis |
| GO:0044782 | cilium organization |
| GO:0046814 | coreceptor-mediated virion attachment to host cell |
| GO:0007010 | cytoskeleton organization |
| GO:0051654 | establishment of mitochondrion localization |
| GO:0009566 | fertilization |
| GO:0019064 | fusion of virus membrane with host plasma membrane |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO:0002891 | positive regulation of immunoglobulin mediated immune response |
| GO:0033005 | positive regulation of mast cell activation |
| GO:0045954 | positive regulation of natural killer cell mediated cytotoxicity |
| GO:0002860 | positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target |
| GO:0050862 | positive regulation of T cell receptor signaling pathway |
| GO:0046596 | regulation of viral entry into host cell |
| GO:0030382 | sperm mitochondrion organization |
| GO:0007286 | spermatid development |
| GO:0007289 | spermatid nucleus differentiation |
| GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity |
| GO:0060370 | susceptibility to T cell mediated cytotoxicity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50835 | IG_LIKE |