| Tag | Content |
|---|---|
| Uniprot ID | F1PWL4 |
| Entrez ID | 611060 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_847558.4 |
| Ensembl protein ID | ENSCAFP00000006905 |
| Ensembl nucleotide ID | ENSCAFG00000004626 |
| Gene name | Nectin cell adhesion molecule 2 |
| Gene symbol | NECTIN2 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MARAAALPPS RSSPPLPLLP PLLLLLLLLR ETGAQDVQVR VPSEVRGYLG GTVQLPCHLL 60 PTGPEVRVSQ VTWLHVDATG ASRSVAAFHP SYGPSFRSPQ PGKERLSFVT AGQSTGTRQG 120 TEMELRDATL ALQGLTVEDE GNYTCEFATF PSGTSRGVTW LRAIAQPQNH AETQEVTLSL 180 DPVPVARCVS EGGRPPARIS WFSPLDGEAK ESQISGPVPG TVTVTSRFTL VPLSRVDGVK 240 VTCKVEHESF EEPILLPVTL SVRYPPEVSI SGYDDNWYLG RSEATLSCDV RSKPEPTGYD 300 WSTTAGVFPA SAVAQGPQLI IHSVDRLVNT TFICTVTNAV GTGRAEQVVL VRETPNTAGA 360 GATGGIIGGI IAAIIATAVV ATGILICRQQ RKEQRLQGAE EEDDLEGPPS YKPPAPKAKL 420 EEPEMPSQLF TLGPSEHSPL KTPYFDAGIP CAEQDMPRYH ELPTLEERSG PLLLGATGLG 480 PPMLVSPGPP AMEGVSLDLE DEEEEEDYID KISPIYDALS YSSPSDSYQS KGFVMSRAMY 540 V 541 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NECTIN2 | 505580 | Q17QC7 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 611060 | F1PWL4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | A0A452G7Y9 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | NECTIN2 | 100065463 | F6YWH3 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 5819 | Q92692 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Nectin2 | 19294 | P32507 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 456118 | K6ZRP3 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NECTIN2 | 100038012 | A2TEQ2 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nectin2 | 308417 | A0A0G2KA71 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0009986 | cell surface |
| GO:0044291 | cell-cell contact zone |
| GO:0016021 | integral component of membrane |
| GO:0005886 | plasma membrane |
| GO:0005915 | zonula adherens |
| GO:0050839 | cell adhesion molecule binding |
| GO:0042803 | protein homodimerization activity |
| GO:0001675 | acrosome assembly |
| GO:0032990 | cell part morphogenesis |
| GO:0044782 | cilium organization |
| GO:0046814 | coreceptor-mediated virion attachment to host cell |
| GO:0007010 | cytoskeleton organization |
| GO:0051654 | establishment of mitochondrion localization |
| GO:0009566 | fertilization |
| GO:0019064 | fusion of virus membrane with host plasma membrane |
| GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules |
| GO:0002891 | positive regulation of immunoglobulin mediated immune response |
| GO:0033005 | positive regulation of mast cell activation |
| GO:0002860 | positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target |
| GO:0050862 | positive regulation of T cell receptor signaling pathway |
| GO:0046596 | regulation of viral entry into host cell |
| GO:0030382 | sperm mitochondrion organization |
| GO:0007289 | spermatid nucleus differentiation |
| GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity |
| GO:0060370 | susceptibility to T cell mediated cytotoxicity |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50835 | IG_LIKE |