Gene: NECTIN2

Basic information

Tag Content
Uniprot ID F6YWH3
Entrez ID 100065463
Genbank protein ID
Genbank nucleotide ID XM_003362328.3
Ensembl protein ID ENSECAP00000007402
Ensembl nucleotide ID ENSECAG00000009306
Gene name Nectin cell adhesion molecule 2
Gene symbol NECTIN2
Organism Equus caballus
NCBI taxa ID 9796
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MARAAALPPS RSLRTLPLLP LLLLLLRETG AQDVQVRVLP EVRGHLGGTV ELPCHLLPPA 60
SEVQVSQVTW MRMDAAGISS NVAVFHPLYG PSFPSPKPGK ERLSFVTARQ SPGAGQGAKM 120
ELRDATLALG GLTVEDEGNY TCEFATFPQG TGRGVTWLRA IAQPQNRIEK QEVPLSLEPV 180
PVARCVSTGG RPPARISWLS PLDGEARESQ VSGSVPGTVT VTSRFTLVPL GRADGVEVIC 240
KVEHESFKEP DLLSVSLSVR YPPEVSISGY DDNWYLGRSE ATLSCDVRSN PEPTGYDWST 300
TSGTLPASAV AQGPQLIIHS VDKLVNTTFI CTVTNAVGTG RAEQVVLVRE TPNTAGAGAT 360
GGIIGGIIAA IIATAVAATG IIICRQQQKE QGLQGAEEED DQEGPPSYKP PTPKAKLEEP 420
EMPSQLFTLG ASEHSPLKTP YFDAGVPCAE QELPRYHELP TLEERSGPLL TGAMSLGSPI 480
LVPPGPPAVE EVSLDLENEE EEEEEEDYLD KINPIYDALS YSSPPDSYQS KGFVMSRAMY 540
V 541

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNECTIN2505580Q17QC7Bos taurusPredictionMore>>
1:1 orthologNECTIN2611060F1PWL4Canis lupus familiarisPredictionMore>>
1:1 orthologNECTIN2A0A452G7Y9Capra hircusPredictionMore>>
1:1 orthologNECTIN2100065463F6YWH3Equus caballusPredictionMore>>
1:1 orthologNECTIN25819Q92692Homo sapiensPublicationMore>>
1:1 orthologNectin219294P32507Mus musculusPredictionMore>>
1:1 orthologNECTIN2456118K6ZRP3Pan troglodytesPredictionMore>>
1:1 orthologNECTIN2100038012A2TEQ2Sus scrofaPredictionMore>>
1:1 orthologNectin2308417A0A0G2KA71Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
GO:0050839 cell adhesion molecule binding
GO:0042803 protein homodimerization activity
GO:0007155 cell adhesion
GO:0007286 spermatid development
GO:0019062 virion attachment to host cell

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0393 Immunoglobulin domain
KW-0472 Membrane
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR033318 Nectin-2

PROSITE

PROSITE ID PROSITE Term
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF08205 C2-set_2
PF07686 V-set