| Tag | Content |
|---|---|
| Uniprot ID | A0A287A740 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000039793 |
| Ensembl nucleotide ID | ENSSSCG00000002039 |
| Gene name | Matrix metalloproteinase-14 |
| Gene symbol | MMP14 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSPAPRPVRS LLLPLLTLAS ALASLSSAQS FSPEAWLQQY GYLPPGDLRT HTQRSPQSLS 60 AAIAAMQRFY GLRVTGKADA DTMKAMRRPR CGVPDKFGAE IKANVRRKRY AIQGLKWQHN 120 EITFCIQNYT PKVGEYATFE AIRKAFRVWE SATPLRFREV PYAYIREGHE KQADIMIFFA 180 EGFHGDSTPF DGEGGFLAHA YFPGPNIGGD THFDSAEPWT VRNEDLNGND IFLVAVHELG 240 HALGLEHSND PSAIMAPFYQ WMDTENFVLP DDDRRGIQQL YGSESGFPTK MPPQPRTTSK 300 PSVPDKPKNP TYGPNICDGN FDTVAMLRGE MFVFKERWFW RVRKNQVMDG YPMPIGQFWR 360 GLPASINTAY ERKDGKFVFF KGDKHWVFDE ASLEPGYPKH IKELGRGLPT DKIDAALFWM 420 PNGKTYFFRG NKYYRFNEEL RAVDSEYPKN IKVWEGIPES PRGSFMGSDE VFTYFYKGNK 480 YWKFNNQKLK VEPGYPKSAL RDWMGCPSGG RPDEGTEEET EVIIIEVDEE GSGAVSAAAV 540 VLPVLLLLLV LAVGLAVFFF RRHGTPKRLL YCQRSLLDKV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP14 | 403823 | F1PXM2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP14 | A0A452E6Q2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP14 | 4323 | P50281 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mmp14 | 17387 | P53690 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MMP14 | 742887 | H2Q7Z4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP14 | A0A287A740 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp14 | 81707 | Q10739 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mmp14b | 566945 | B0R0I1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0016021 | integral component of membrane |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021805 | Pept_M10A_metallopeptidase_C |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |
| IPR036366 | PGBDSf |