| Tag | Content |
|---|---|
| Uniprot ID | A0A452E6Q2 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000007643 |
| Ensembl nucleotide ID | ENSCHIG00000011010 |
| Gene name | ZnMc domain-containing protein |
| Gene symbol | MMP14 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MYVKAWLQQY GYLPPGDLRT HTQRSPQSLS AAIAAMQRFY GLRVTGKADA DTMKAMRRPR 60 CGVPDKFGAE IKANVRRKRY AIQGLKWQHN EITFCIQNYT PKVGEYATFE AIRKAFRVWE 120 SATPLRFREV PYAYIREGHE KQADIMIFFA EGFHGDSTPF DGEGGFLAHA YFPGPNIGGD 180 THFDSAEPWT VRNEDLNGND IFLVAVHELG HALGLEHSND PSAIMAPFYQ WMDTENFVLP 240 DDDRRGIQQL YGSKSGSPTK IPPQPRTTSR PSIPDKPKNP TYGPNICDGN FDTVAMLRGE 300 MFVFKERWFW RVRKNQVMDG YPMPIGQFWR GLPASINTAY ERKDGKFVFF KGDKHWVFDE 360 ASLEPGYPKH IKELGRGLPT DRIDAALFWM PNGKTYFFRG NKYYRFNEEL RIVESEYPKN 420 IKVWEGIPES PRGSFMGSDE VFTYFYKGNK YWKFNNQKLK VEPGYPKSAL RDWMGCPSSG 480 GQPDEGTEEE TEVIIIEVDE EGSGAVSAAA VVLPVLLLLL VLAVGLAVFF FRRHGTPKRL 540 LYCQRSLLDK V 551 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MMP14 | 403823 | F1PXM2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MMP14 | A0A452E6Q2 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | MMP14 | 4323 | P50281 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Mmp14 | 17387 | P53690 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | MMP14 | 742887 | H2Q7Z4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MMP14 | A0A287A740 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Mmp14 | 81707 | Q10739 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mmp14b | 566945 | B0R0I1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0031012 | extracellular matrix |
| GO:0016021 | integral component of membrane |
| GO:0004222 | metalloendopeptidase activity |
| GO:0008270 | zinc ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR000585 | Hemopexin-like_dom |
| IPR036375 | Hemopexin-like_dom_sf |
| IPR018487 | Hemopexin-like_repeat |
| IPR018486 | Hemopexin_CS |
| IPR033739 | M10A_MMP |
| IPR024079 | MetalloPept_cat_dom_sf |
| IPR001818 | Pept_M10_metallopeptidase |
| IPR021190 | Pept_M10A |
| IPR021805 | Pept_M10A_metallopeptidase_C |
| IPR021158 | Pept_M10A_Zn_BS |
| IPR006026 | Peptidase_Metallo |
| IPR002477 | Peptidoglycan-bd-like |
| IPR036365 | PGBD-like_sf |