| Tag | Content |
|---|---|
| Uniprot ID | A0A287AGV4 |
| Entrez ID | 100523669 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_003126093.5 |
| Ensembl protein ID | ENSSSCP00000043266 |
| Ensembl nucleotide ID | ENSSSCG00000032861 |
| Gene name | NUAK family kinase 1 |
| Gene symbol | NUAK1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEGAAAAAAG DGPDLGLGTP GSPPEAGAGA TAAPAAAAPE PRKPHGVKRH HHKHNLKHRY 60 ELQETLGKGT YGKVKRATER FSGRVVAIKS IRKDKIKDEQ DMVHIRREIE IMSSLSHPHI 120 ISIYEVFENK DKIVIIMEYA SKGELYDYIS ERRRLSERET RHFFRQIVSA VHYCHKNGVV 180 HRDLKLENIL LDDNCNIKIA DFGLSNLYQK DKFLQTFCGS PLYASPEIVN GRPYRGPEVD 240 SWALGVLLYT LVYGTMPFDG FDHKNLIRQI SSGEYREPTQ PSDARGLIRW MLMVNPDRRA 300 TIEDIANHWW VNWGYKSSVC DCDALHSSES PLLARIIDWH HRSTGLQVEA DAKVKGLAKP 360 GAPEVVLERQ RSLKKSKKEN DFAQSGQDAV PESPSKLSSK RPKGILKKRS NSEHRSHSTG 420 FIEGVVSPAL PPTFKMEQDL CRTAVPLPSS PEAEVPGKLS PKQSATMPKK GILKKTQQRE 480 SGYYSSPERS ESSELLDTND GLGGPVPSPS PPDAARAPPH SLSCRRKGIL KHSSKYSAGT 540 MDPALASPEM PTLESLLEPG VPAEGISRSY SRPSSVISDD SVLSSDSFDL LDLQENRPAR 600 QRIRSCVSAE NFLQIQDFER LQNRPRPQYL KRYRNRLGDS SFSLLTDMDD VTQVYKKALE 660 ICNKLN 666 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK1 | 519892 | E1B9B6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 481296 | J9P812 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 102190764 | A0A452G5R0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 9891 | O60285 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 77976 | Q641K5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK1 | 742637 | H2Q6S1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 100523669 | A0A287AGV4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 299694 | D3ZQN8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0001650 | fibrillar center |
| GO:0015630 | microtubule cytoskeleton |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0002039 | p53 binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
| GO:0030155 | regulation of cell adhesion |
| GO:2000772 | regulation of cellular senescence |
| GO:0035507 | regulation of myosin-light-chain-phosphatase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |