| Tag | Content |
|---|---|
| Uniprot ID | J9P812 |
| Entrez ID | 481296 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_538417.4 |
| Ensembl protein ID | ENSCAFP00000041801 |
| Ensembl nucleotide ID | ENSCAFG00000001879 |
| Gene name | NUAK family kinase 1 |
| Gene symbol | NUAK1 |
| Organism | Canis lupus familiaris |
| NCBI taxa ID | 9615 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEGAAAPAAR DGPDLRPGAP GSPPEVVAGA TAAPAAAAPE PRKPHGVKRH HHKHNLKHRY 60 ELQETLGKGT YGKVKRATER FSGRVVAIKS IRKDKIKDEQ DMVHIRREIE IMSSLNHPHI 120 ISIYEVFENK DKIVIIMEYA SKGELYDYIS ERRRLSERET RHFFRQIVSA VHYCHKNGVV 180 HRDLKLENIL LDDNCNIKIA DFGLSNLYQK DKFLQTFCGS PLYASPEIVN GRPYRGPEVD 240 SWALGVLLYT LVYGTMPFDG FDHKNLIRQI SSGEYREPTQ PSDARGLIRW MLMVNPDRRA 300 TIEDIANHWW VNWGYKSSVC DCDALHNSES PLLARIIDWH HRSTGLQAEA DAKIKGLAKP 360 GASEVMLERQ RSLKKSKKEN DFAQSGQDPM PESPNKLTSK RPKGILKKRS NSEHRSHSTG 420 FIEGVVSPAL PSAFKIEPDV CRTGVAVPSS PEADVPGKLS PKQSATMPKK GILKKTQQRE 480 SGYYSSPERS ESSELLDSQD GPGSGLPSPS PPDPARGPVL GLSCRRKGIL KHSSKYSAGS 540 TDPALASPDV PTLESLLEPG APPEGLSRSY SRPSSVISDD SVLSSDSFDL LDLQENRPAR 600 QRLRSCVSAE NFLQIQDFEG LQNRPRPQYL KRYRNRLGDS SFSLLMDMDD VTQVYKKALE 660 ICNKLN 666 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK1 | 519892 | E1B9B6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 481296 | J9P812 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 102190764 | A0A452G5R0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 9891 | O60285 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 77976 | Q641K5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK1 | 742637 | H2Q6S1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 100523669 | A0A287AGV4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 299694 | D3ZQN8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0001650 | fibrillar center |
| GO:0015630 | microtubule cytoskeleton |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0002039 | p53 binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
| GO:0030155 | regulation of cell adhesion |
| GO:2000772 | regulation of cellular senescence |
| GO:0035507 | regulation of myosin-light-chain-phosphatase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |