| Tag | Content |
|---|---|
| Uniprot ID | A0A452G5R0 |
| Entrez ID | 102190764 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005680647.3 |
| Ensembl protein ID | ENSCHIP00000031918 |
| Ensembl nucleotide ID | ENSCHIG00000026094 |
| Gene name | Protein kinase domain-containing protein |
| Gene symbol | NUAK1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEGAAAPAAG PDLGPGAPGS PPEAGAIAAP SAAGPEPRKP HGVKRHHHKH NLKHRYELQE 60 TLGKGTYGKV KRATERFSGR VVAIKSIRKD KIKDEQDMVH IRREIEIMSS LSHPHIISIY 120 EVFENKDKIV IIMEYASKGE LYDYISERRR LSERETRHFF RQIVSAVHYC HKNGVVHRDL 180 KLENILLDDN CNIKIADFGL SNLYQKDKFL QTFCGSPLYA SPEIVNGRPY RGPEVDSWAL 240 GVLLYTLVYG TMPFDGFDHK NLIRQISSGE YREPTQPSDA RGLIRWMLMV NPDRRATIED 300 IANHWWVNWG YKSSVCDCDA LHSSESPLLA RIIDWHHRST GLQAEAEAKI KGLAKPGAPE 360 VVLERQRSLK KSKKENDFPQ SGQDSVPESP SKLSSKRPKG ILKKRSNSEH RSHSTGFIEG 420 VVSPALPPTF KLEQDLCRTA VPLPSPPEAE VPGKLSPKQS VTMPKKGILK KTQQRESGYY 480 SSPERSESSE LLDSNDGLGS SIPSPSPPDP ARVPSHSLSC RRKGILKHSS KYSAGTTDPA 540 LASPEMPTLE SLLEPGVPTE GLSRSYSRPS SVISDDSVLS SDSFDLLDLQ ENRPTRQRIR 600 SCVSAENFLQ IQDFEGLQNR PRPQYLKRYR NRLADSSFSL LTDMDDVTQV YKKALEICNK 660 LN 662 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK1 | 519892 | E1B9B6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 481296 | J9P812 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 102190764 | A0A452G5R0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 9891 | O60285 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 77976 | Q641K5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK1 | 742637 | H2Q6S1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 100523669 | A0A287AGV4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 299694 | D3ZQN8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0001650 | fibrillar center |
| GO:0015630 | microtubule cytoskeleton |
| GO:0005654 | nucleoplasm |
| GO:0005524 | ATP binding |
| GO:0002039 | p53 binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0030155 | regulation of cell adhesion |
| GO:2000772 | regulation of cellular senescence |
| GO:0035507 | regulation of myosin-light-chain-phosphatase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |