| Tag | Content |
|---|---|
| Uniprot ID | H2Q6S1; A0A2J8MZS0; |
| Entrez ID | 742637 |
| Genbank protein ID | JAA14530.1 |
| Genbank nucleotide ID | XM_001161041.4 |
| Ensembl protein ID | ENSPTRP00000009145 |
| Ensembl nucleotide ID | ENSPTRG00000005386 |
| Gene name | NUAK family kinase 1 |
| Gene symbol | NUAK1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEGAAAPVAG DRPDLGLGAP GSPREAVAGA TAALEPRKPH GVKRHHHKHN LKHRYELQET 60 LGKGTYGKVK RATERFSGRV VAIKSIRKDK IKDEQDMVHI RREIEIMSSL NHPHIISIYE 120 VFENKDKIVI IMEYASKGEL YDYISERRRL SERETRHFFR QIVSAVHYCH KNGVVHRDLK 180 LENILLDDNC NIKIADFGLS NLYQKDKFLQ TFCGSPLYAS PEIVNGRPYR GPEVDSWALG 240 VLLYTLVYGT MPFDGFDHKN LIRQISSGEY REPTQPSDAR GLIRWMLMVN PDRRATIEDI 300 ANHWWVNWGY KSSVCDCDAL HDSESPLLAR IIDWHHRSTG LQADTEAKMK GLAKPTTSEV 360 MLEQQRSLKK SKKENDFAQS SQDAVPESPS KLSSKRPKGI LKKRSNSEHR SHSTGFIEGV 420 VGPALPSTFK MEQDLCRTGV LLPSSPEAEV PGKLSPKQSA TMPKKGILKK TQQRESGYYS 480 SPERSESSEL LDSNDVMGSS IPSPSPPDPA RVTSHSLSCR RKGILKHSSK YSAGTMDPAL 540 VSPEMPTLES LSEPGVPAEG LSRSYSRPSS VISDDSVLSS DSFDLLDLQE NRPARQRIRS 600 CVSAENFLQI QDFEGLQNRP RPQYLKRYRN RLADSSFSLL TDMDDVTQVY KQALEICSKL 660 N 661 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK1 | 519892 | E1B9B6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 481296 | J9P812 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 102190764 | A0A452G5R0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 9891 | O60285 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 77976 | Q641K5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK1 | 742637 | H2Q6S1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 100523669 | A0A287AGV4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 299694 | D3ZQN8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0001650 | fibrillar center |
| GO:0015630 | microtubule cytoskeleton |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0002039 | p53 binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
| GO:0030155 | regulation of cell adhesion |
| GO:2000772 | regulation of cellular senescence |
| GO:0035507 | regulation of myosin-light-chain-phosphatase activity |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |