| Tag | Content |
|---|---|
| Uniprot ID | E1B9B6 |
| Entrez ID | 519892 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001205496.1 |
| Ensembl protein ID | ENSBTAP00000013805 |
| Ensembl nucleotide ID | ENSBTAG00000010457 |
| Gene name | NUAK family kinase 1 |
| Gene symbol | NUAK1 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEGAAAPAAG PDLGPGAPGS PPEAGASAAP SAATPEPRKP HGVKRHHHKH NLKHRYELQE 60 TLGKGTYGKV KRATERFSGR VVAIKSIRKD KIKDEQDMVH IRREIEIMSS LNHPHIISIY 120 EVFENKDKIV IIMEYASKGE LYDYISERRR LSERETRHFF RQIVSAVHYC HKNGVVHRDL 180 KLENILLDDN CNIKIADFGL SNLYQKDKFL QTFCGSPLYA SPEIVNGRPY RGPEVDSWAL 240 GVLLYTLVYG TMPFDGFDHK NLIRQISSGE YREPTQPSDA RGLIRWMLMV NPDRRATIED 300 IANHWWVNWG YKSSVCDCDA LHSSESPLLA RIIDWHHRST GLQAEAEAKV KGLAKPGAPE 360 VVLERQRSLK KSKKENDFPQ SGQDSVPESP SKLSSKRPKG ILKKRSNSEH RSHSTGFIEG 420 VVSPALPPTF KLEQDLCRTA VPLPSPPEAE VPGKLSPKQS ATMPKKGILK KTQQRESGYY 480 SSPERSESSE LLDSNDGLGS SIPSPSPPDP ARVPSHSLSC RRKGILKHNS KYSAGTMDPA 540 LASPEMPTLE SLLEPGVPSE GLSRSYSRPS SVISDDSVLS SDSFDLLDLQ ENRPTRQRIR 600 SCVSAENFLQ IQDFEGLQNR PRPQYLKRYR NRLADSSFSL LTDMDDVTQV YKKALEICNK 660 LN 662 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NUAK1 | 519892 | E1B9B6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 481296 | J9P812 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 102190764 | A0A452G5R0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 9891 | O60285 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 77976 | Q641K5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NUAK1 | 742637 | H2Q6S1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | NUAK1 | 100523669 | A0A287AGV4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Nuak1 | 299694 | D3ZQN8 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0001650 | fibrillar center |
| GO:0015630 | microtubule cytoskeleton |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0002039 | p53 binding |
| GO:0004674 | protein serine/threonine kinase activity |
| GO:0035556 | intracellular signal transduction |
| GO:0006468 | protein phosphorylation |
| GO:0030155 | regulation of cell adhesion |
| GO:2000772 | regulation of cellular senescence |
| GO:0035507 | regulation of myosin-light-chain-phosphatase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| Pfam ID | Pfam Term |
|---|---|
| PF00069 | Pkinase |