| Tag | Content |
|---|---|
| Uniprot ID | A0A287BCU5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000053915 |
| Ensembl nucleotide ID | ENSSSCG00000036572 |
| Gene name | Beta-carotene oxygenase 1 |
| Gene symbol | BCO1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDILFGRNKK EQLEPVRARV TGKIPSWLQG ILLRNGPGMH TVGETKYNHW FDGLALLHSF 60 TIRDGEVYYR SKYLRSDTYN ANIEANRIVV SEFGTMAYPD PCKNIFSKAF SYLSHTIPDF 120 TDNCLINIMK CGEDCYATTE TNYIRRINPL TLETLEKVDY RKYVAVNVAT SHPHYDATGN 180 VLNIGTSIVD KGKTKYVIFK IPATAPEDGK KGRGPLKHTE VFCSIASRSL LSPSYYHSFG 240 VTENYVVFLE QPFRMDILKM ATAYIRGVSW ASCLAFHGED KTYIHVIDQR TRKPVLSKFY 300 TDPMVVFHHV NAYEEDGCLV FDVIAYEDSS LYQLFYLAHL NEDFEENSRL TSVPTLKRFA 360 VPLHVDKDAD VGSNLIKLAS TTARALKEKD DQIYCQPELL CKGLELPRIN YAYNGKPYRY 420 VFAAEVQWSP IPTKVIKYDL LTKSSLSWGE AHCWPAEPLF VPTPGARDED DGIILSAIVS 480 TDPQKLPFLL VLDAKTFTEL ARASVDVDMH LDLHGLFIPG TAWDVKKQTP SQEEQGRAVD 540 HGVAPRT 547 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BCO1 | 102179507 | A0A452FQT3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | BCO1 | 53630 | Q9HAY6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Bco1 | 63857 | Q9JJS6 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | BCO1 | 468043 | H2QBK9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | BCO1 | A0A287BCU5 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | BCO1 | 100358087 | G1SEP0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Bco1 | 114106 | G3V7N1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | bco1 | 84039 | Q7ZTS0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0003834 | beta-carotene 15,15'-monooxygenase activity |
| GO:0046872 | metal ion binding |
| GO:1901810 | beta-carotene metabolic process |
| GO:0042574 | retinal metabolic process |
| InterPro ID | InterPro Term |
|---|---|
| IPR004294 | Carotenoid_Oase |
| Pfam ID | Pfam Term |
|---|---|
| PF03055 | RPE65 |